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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:00 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Shoulder Pain
Interventions: Active BFRT, Sham BFRT, Strengthening Exercises with BFRT, Skilled Physical Therapy Care; Device · Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 50 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Bipolar II Disorder, Bipolar II Disorder, Most Recent Episode Major Depressive
Interventions: Device: Stimulation-ON, Device: Stimulation-OFF, Device: Stimulation -ON Active Control; Device
Lead sponsor: Andrew Krystal; Other
Eligibility: 22 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2035
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Ischemia-Reperfusion Injury
Interventions: autoRIC, autoRIC Sham; Device
Lead sponsor: CellAegis US, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 14
States / cities: Birmingham, Alabama • Danbury, Connecticut • Jacksonville, Florida + 10 more

Conditions: Depression, Depressive Disorder, Depressive Disorder, Treatment-resistant, Depressive Disorder, Major
Interventions: LFMS; Device
Lead sponsor: Tal Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 12
States / cities: Garden Grove, California • Lemon Grove, California • Oakland, California + 9 more

Conditions: Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
Interventions: Session A: Positive Placebo + Active tTIS, Session B: Positive Placebo + Sham tTIS, Session C: Negative Placebo + Active tTIS, Session D: Negative Placebo + Sham tTIS, Session E: On-Placebo + Sham tTIS, Session F: Off-Placebo + Sham tTIS; Behavioral
Lead sponsor: Trustees of Dartmouth College; Other
Eligibility: 18 Years to 55 Years
Enrollment: 196 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Hanover, New Hampshire

Conditions: Stroke, Fatigue, Chronic Stroke, Stroke Sequelae
Interventions: anodal transcranial direct current stimulation (a-tDCS), sham stimulation; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 35 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Fibromyalgia (FM), Posttraumatic Stress Disorder (PTSD)
Interventions: tAN plus PEPC, sham plus PEPC; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Pupillary Response
Interventions: Transcutaneous Auricular Vagal Nerve Stimulation (taVNS), Sham Stimulation; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Traumatic Stress Disorder
Interventions: Low Field Magnetic Stimulation; Device
Lead sponsor: Mclean Hospital; Other
Eligibility: 21 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Traumatic Brain Injury, Chronic Balance Disorder
Interventions: Cranial nerve non-invasive neuromodulation via PoNS device, Sham PoNS device; Device
Lead sponsor: Helius Medical Inc; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Orlando, Florida • Portland, Oregon

Conditions: Restless Legs Syndrome
Interventions: NTX100 Neuromodulation System - Active, NTX100 Neuromodulation System - Sham; Device
Lead sponsor: Noctrix Health, Inc.; Industry
Eligibility: 22 Years to 89 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Menlo Park, California • San Ramon, California • St Louis, Missouri

Conditions: Irritable Bowel Syndrome, Abdominal Pain, Autonomic Nervous System Imbalance
Interventions: Peripheral Electrical Nerve Field Stimulation (PENFS) Device, Sham Device; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 60 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Gastroparesis
Interventions: Sham vibrating capsule, Vibrant Capsule (1 vibration), Vibrant Capsule (3 vibration), Vibrant Capsule (5 vibration); Device
Lead sponsor: Vibrant Ltd.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Alcohol Use Disorder, Chronic Pain
Interventions: Episodic Future Thinking, Control Episodic Thinking, Low-intensity Focused Ultrasound, Sham Low-intensity Focused Ultrasound; Behavioral · Device
Lead sponsor: Kirstin M Gatchalian; Other
Eligibility: 21 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Age-Related Macular Degeneration, Age-related Macular Degeneration (ARMD), Intermediate AMD, Geographic Atrophy Secondary to Age-related Macular Degeneration
Interventions: i-Lumen AMD; Device
Lead sponsor: i-Lumen Scientific AUS PTY LTD; Industry
Eligibility: 60 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 7
States / cities: Poway, California • Manchester, Connecticut • Lemont, Illinois + 4 more

Conditions: COVID19
Interventions: RD-X19; Device
Lead sponsor: EmitBio Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Miami, Florida • College Station, Texas

Conditions: Drug Use Disorder
Interventions: Electrical Stimulation, Sham intervention; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Low Back Pain
Interventions: foot orthotics, Sham foot orthotic; Device
Lead sponsor: Logan College of Chiropractic; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Nasal Airway Obstruction
Interventions: Vivaer ARC Stylus, Sham; Device
Lead sponsor: Aerin Medical; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 12
States / cities: Roseville, California • Torrance, California • Coral Springs, Florida + 9 more

Conditions: Cognitive Control, Memory
Interventions: Sham device, STARSTIM Device in-phase, STARSTIM Device anti-phase; Device
Lead sponsor: Florida International University; Other
Eligibility: 18 Years to 59 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Ischemic Cardiomyopathy
Interventions: Low level tragus stimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 90 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Depression
Interventions: Nexalin Based Trans-Cranial Electrical Stimulation; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Belle Mead, New Jersey

Conditions: Migraine
Interventions: insufflation, placebo insufflation; Device
Lead sponsor: Caps Research Network; Other
Eligibility: 20 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Prescott, Arizona • Scottsdale, Arizona

Conditions: Post COVID-19 Condition (PCC)
Interventions: RDX-19; Device
Lead sponsor: EmitBio Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: East Amherst, New York • Milan, Tennessee

Search by objective public record fields.

BFRT for Subacromial Pain

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Remote Ischemic Conditioning Using the autoRIC

Low Field Magnetic Stimulation (LFMS) in Subjects With Treatment-Resistant Depression (TRD)

Neural Mechanisms of Interpersonal Expectations on Negative Affect

Post-stroke Fatigue, Inflammation, tDCS

Treatment of Fibromyalgia and PTSD With Live and Inactive Vagus Nerve Stimulation With PEPC

taVNS on Pupillary Response and Perceptual Learning

A Pilot Study of Low Field Magnetic Stimulation in PTSD: Three Daily Treatments

Study of Safety and Effectiveness of PoNS Device to Treat Chronic Balance Deficit Due to Traumatic Brain Injury (TBI)

Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS

Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome

Effect of Vibrant Capsule on Gastric Emptying and Antropyloroduodenal Motility in Healthy Volunteers

Decision Making in Chronic Pain and Alcohol Use Disorder

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

Phase I/II Safety, Dose Finding & Antiviral Activity of RD-X19 in Mild/Moderate Outpatient COVID-19

Neuromodulation of Executive Control for Substance Use Disorders

Duration of Spinal Manipulation Effects as Influenced by Orthotics

Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study

Synchronization of Theta to Influence Memory

The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy

The Safety and Efficacy of Nexalin Trans-cranial Electrical Stimulation Stimulation for the Treatment of Depression

Feasibility of Using a Mobile Device Controlled Micro-pressure Pulse Insufflator for Acute Migraine Relief

Pilot Randomized Study of RD-X19 Tx Device in Subjects With PCC (Long Covid) in the Outpatient Setting