Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Pain, Chronic, Irritable Bowel Syndrome, Symptom Cluster
Interventions: Home-based taVNS intervention; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 29 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alzheimer Disease
Interventions: Intermittent theta burst stimulation active coil, Sham coil; Device
Lead sponsor: HealthPartners Institute; Other
Eligibility: 40 Years to 90 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: MDD
Interventions: Relivion®DP- Active, Relivion®DP- Sham; Device
Lead sponsor: Neurolief Ltd.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 12
States / cities: La Jolla, California • Los Angeles, California • Miami Lakes, Florida + 8 more

Conditions: Cystoscopy
Interventions: Percutaneous Tibial Nerve Stimulation (PTNS), Sham Percutaneous Tibial Nerve Stimulation (PTNS), Standard Cystoscopy; Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Dyslexia, Reading Disability
Interventions: Active transcranial electrical stimulation (tES), Sham transcranial electrical stimulation (tES); Device
Lead sponsor: General Neuro Inc.; Industry
Eligibility: 7 Years to 17 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Spinal Cord Injuries
Interventions: TNM at a sham-point (AccelBand) - randomized arm, TNM at a leg point (AccelBand)- randomized arm, TNM at a leg point (AccelBand)- open-label; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Androgenetic Alopecia
Interventions: X5 HairLaser, X5 Hair Laser Sham Device; Device
Lead sponsor: Spencer Forrest, Inc.; Industry
Eligibility: 20 Years to 60 Years · Male only
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 3
States / cities: Hot Springs, Arkansas • St. Petersburg, Florida • New York, New York

Conditions: Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia, Cooling, Occupational Exposure, Occupational Health, Hidden Hearing Loss
Interventions: Cold pack-delivered mild therapeutic hypothermia; Device
Lead sponsor: Restorear Devices LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Nicotine Dependence
Interventions: Transcranial Magnetic Stimulation (Neuronetics), Sham Transcranial Magnetic Stimulation; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 50 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: Parasym (TM) Transcutaneous Electrical Nerve Stimulation (TENS) Device; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Overactive Bladder
Interventions: TheraNova Neuromodulation System; Device
Lead sponsor: Theranova, L.L.C.; Industry
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Sacramento, California • Stanford, California

Conditions: Chronic Non-specific Low Back Pain
Interventions: Automatic Thermo-mechanical Massage Bed; Device
Lead sponsor: The City College of New York; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy, Clavicle Fracture
Interventions: Experimental Treatment, Sham Comparator; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Facial Pain
Interventions: SinuSonic, Sham Device; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Keratoconus
Interventions: Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment, Placebo and sham treatment; Combination Product
Lead sponsor: Epion Therapeutics; Industry
Eligibility: 8 Years to 45 Years
Enrollment: 396 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 13
States / cities: Rowland Heights, California • San Francisco, California • Miami, Florida + 10 more

Conditions: Pain Management
Interventions: TENS, Sham TENS; Device
Lead sponsor: Ashley Turner, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Supraspinatus Tendinitis, Shoulder Pain
Interventions: TrueRelief device, Sham TrueRelief device; Device
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Stroke
Interventions: tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT), Sham tDCS: placebo noninvasive brain stimulation; Procedure · Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 21 Years and older
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions: High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy; Other
Lead sponsor: Brigham Young University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Provo, Utah

Conditions: Episodic Migraine, Migraine With Aura, Migraine Without Aura, Migraine
Interventions: Mi-Helper; Device
Lead sponsor: CoolTech LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: photobiomodulation, Sham treatment, Physiotherapy; Device · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Type 2 Diabetes
Interventions: Vestal DM Active device, Lifestyle modification, Vestal DM Sham device; Device · Behavioral
Lead sponsor: Neurovalens Ltd.; Industry
Eligibility: 22 Years to 70 Years
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 15
States / cities: Birmingham, Alabama • La Jolla, California • Sacramento, California + 12 more

Conditions: Cystic Fibrosis
Interventions: inhaled hypertonic saline (7%); Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity
Interventions: placement of g-Cath EZ suture anchors, Sham procedure, Diet and Exercise; Device · Procedure · Behavioral
Lead sponsor: USGI Medical; Industry
Eligibility: 22 Years to 60 Years
Enrollment: 377 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 11
States / cities: Scottsdale, Arizona • Miami, Florida • Dalton, Georgia + 8 more

Search by objective public record fields.

Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

TMS Pilot in Early AD II

The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)

Utilization of PTNS During Office-Based Cystoscopy

Brain Stimulation Paired With Structured Reading Instruction in Children With Dyslexia

Efficacy of a Wearable Noninvasive Neuromodulation Device

A Randomized, Double-blind Clinical Trial to Evaluate the Safety and Efficacy of the X5 HairLaser for the Treatment of Androgenetic Alopecia in Males

Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss

Transcranial Magnetic Stimulation Effects on Nicotine Craving

Vagus Nerve Stimulation in Treatment of Postural Orthostatic Tachycardia Syndrome

Evaluation of the TheraNova Neuromodulation System for the Treatment of Overactive Bladder Symptoms

Automatic Thermomechanical Massage Bed for Acute Pain Relief for Chronic Nonspecific Low Back Pain

Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery

Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration With Oscillating Expiratory Pressure

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation

TrueRelief Efficacy for Supraspinatus Tendonitis

Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery

Heat Therapy and Muscle Function Study

Mi-Helper Transnasal Cooling for Acute Treatment of Migraine

Photobiomodulation Therapy Using the Realief Therapy System for the Treatment of Chemotherapy-associated Peripheral Neuropathy

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus

A Study of Lung Clearance After Hypertonic Saline Delivery Using the tPAD Device

The USGI Medical ESSENTIAL Study for Weight Loss