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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:09 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Mal de Debarquement Syndrome
Interventions: Transcranial Electrical Stimulation; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Bones Stress Injury, Bone Stress Fracture
Interventions: Extracorporeal shockwave treatment (ESWT)., Sham Device; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 50 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: Los Angeles, California • Redwood City, California • Cambridge, Massachusetts + 1 more

Conditions: Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis, Alzheimer's Disease and Related Dementias, Parkinson's Disease, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Dementia (Diagnosis), Dementia MCI (Mild Cognitive Impairment)
Interventions: Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental, Control - Placebo Comparator; Behavioral · Device · Biological + 1 more
Lead sponsor: Noah Tech, Corp.; Industry
Eligibility: 55 Years and older
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Palisades Park, New Jersey

Conditions: Post Traumatic Stress Disorder
Interventions: SmartSleep device; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 14 Years to 18 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions: Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (Sham TMS); Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Asthma in Children, Obesity, Pediatric Obesity, Pediatric Asthma
Interventions: Pro2 - Low Dose - 40% of participant's MIP, Pro2 - High Dose - 75% of participant's MIP, Pro2 - SHAM - 15% of participant's MIP; Device
Lead sponsor: Duke University; Other
Eligibility: 6 Years to 17 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Durham, North Carolina

Conditions: Knee Osteoarthritis
Interventions: Ivivi SofPulse; Device
Lead sponsor: Amp Orthopedics, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hemostasis, Blood Biomarkers
Interventions: Volta System; Device
Lead sponsor: Spark Biomedical, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Pain, Metastatic Breast Cancer, Prostate Cancer, Colorectal Cancer
Interventions: Quell, Sham Quell; Device
Lead sponsor: Scripps Translational Science Institute; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Obstructive Sleep Apnea
Interventions: Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment; Device · Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 79 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Baacterial Colonization, Urinary Tract Infections
Interventions: UroShield; Device
Lead sponsor: Rosenblum, Jonathan I., DPM; Individual
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Elmsford, New York

Conditions: Irritable Bowel Syndrome (IBS-C)
Interventions: Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation; Device
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
Interventions: Photobiomodulation, Routine Oral Care and Analgesia; Device · Other
Lead sponsor: MuReva Phototherapy Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 12
States / cities: Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more

Conditions: Drug-Resistant Epilepsy, Epilepsy, Epilepsy (Treatment Refractory), Epilepsy Comorbidities, Epilepsy, Drug Resistant, Epilepsy, Generalized, Epilepsy, Focal
Interventions: Target optimization using LIFU, Serial LIFU stimulation; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Age-Related Macular Degeneration, Dry Age-related Macular Degeneration, Nonexudative Age-related Macular Degeneration
Interventions: i-Lumen(TM) AMD, i-Lumen(TM) AMD Sham; Device
Lead sponsor: i-Lumen Scientific, Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 10
States / cities: Phoenix, Arizona • Walnut Creek, California • Lemont, Illinois + 7 more

Conditions: Urinary Retention
Interventions: PTNS Active Treatment, Sham treatment; Device · Other
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 18 Years to 95 Years · Female only
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Lower Back Pain Chronic
Interventions: peripheral magnetic stimulation, Home exercise; Device · Behavioral
Lead sponsor: Joe X. Zhang; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Edwards Air Force Base, California

Conditions: Pain, Postoperative Complications
Interventions: Acupuncture, Sham Acupuncture, Standard medical care; Procedure
Lead sponsor: HealthEast Care System; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Woodbury, Minnesota

Conditions: Migraine With or Without Aura, Migraine, Migraine Headache
Interventions: Mi-Helper; Device
Lead sponsor: Mi-Helper, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Indian Harbour Beach, Florida

Conditions: Pelvic Pain, Chronic Pain
Interventions: Active tDCS with guided imagery, Active tDCS alone (no guided imagery), Sham tDCS with guided imagery, Sham tDCS alone (no guided imagery); Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 64 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Royal Oak, Michigan

Conditions: Muscle Tension Dysphonia
Interventions: Breathing training without a device, Breathing training with a device; Behavioral
Lead sponsor: Syracuse University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Pain, Postoperative
Interventions: Percutaneous auricular neurostimulation, Sham percutaneous auricular neurostimulation; Device
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Autism Spectrum Disorder
Interventions: Mente Autism™, Sham; Device
Lead sponsor: Carrick Institute for Graduate Studies; Other
Eligibility: 2 Years to 18 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Bimalleolar Ankle Fractures
Interventions: Active Combined Magnetic Field OL1000 Bone Growth Stimulator, Sham Combined Magnetic Field OL1000 Bone Growth Stimulator; Device
Lead sponsor: Encore Medical, L.P.; Industry
Eligibility: 21 Years and older
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 9
States / cities: Tucson, Arizona • Los Angeles, California • Hollywood, Florida + 6 more

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Transcranial Electrical Stimulation for Mal de Debarquement Syndrome

Extracorporeal Shockwave Therapy (ESWT) for the Management of Stress Fractures and High-grade Bone Stress Injuries (BSIs)

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder

Transcranial Magnetic Stimulation for Attention Deficit/Hyperactivity Disorder (ADHD)

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

Effectiveness Study of the Ivivi SofPulse for Pain Amelioration in Adults With Mild to Moderate Knee Osteoarthritis

Delivering Transcutaneous Auricular Neurostimulation to Regulate Platelet Activity in Healthy Human Subjects

Quell Opioid Reduction and Pain Relief in Patients With Cancer

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

The Effect of Surface Acoustic Waves on the Prevention of Colonization in Longterm Indwelling Urinary Caatheters

Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)

Treatment for Acute Postoperative Voiding Dysfunction

Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.

Acupuncture for Pain Management After Hip or Knee Arthroplasty

Cooling to Alleviate Migraine #3

Study of the Acute Effects of Guided Imagery and tDCS on Pain Levels in Women With Chronic Pelvic Pain

The Effects of Respiratory Training on Voice

Auricular Percutaneous Electrical Nerve Field Stimulation for Postoperative Pain Control in Adults

Neurofeedback Therapy for Children Diagnosed With Autism

CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures