Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:02 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Treatment Resistant Depression (TRD), Major Depressive Disorder (MDD)
Interventions: Spaced Transcranial Direct Current Stimulation (tDCS), Sham Spaced tDCS; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 70 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: San Diego, California

Conditions: Parkinson Disease
Interventions: Celeste Specialized Phototherapy Device; Device
Lead sponsor: PhotoPharmics, Inc.; Industry
Eligibility: 45 Years and older
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Major Depressive Disorder
Interventions: Cranial Electrotherapy Stimulation, Sham Cranial Electrotherapy Stimulation; Device
Lead sponsor: Electromedical Products International, Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Forest, Virginia

Conditions: Obese, Pregnancy, Sleep Disordered Breathing
Interventions: CPAP, sham-CPAP, Sleep hygiene; Device · Other
Lead sponsor: Francesca Facco, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Healthy, Pain
Interventions: Selective Nerve Stimulation (SNS) stimulator device; Device
Lead sponsor: Codman & Shurtleff; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Raynham, Massachusetts

Conditions: Anhedonia
Interventions: active tDCS, sham tDCS; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 50 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Nicotine Dependence
Interventions: Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing; Device · Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Androgenetic Alopecia, Hair Loss, Female Pattern Baldness
Interventions: HairMax LaserComb 2009 model 12 beam, Sham Device; Device
Lead sponsor: Lexington International, LLC; Industry
Eligibility: 25 Years to 60 Years · Female only
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 3
States / cities: Miami, Florida • Minneapolis, Minnesota • Cleveland, Ohio

Conditions: Parkinson Disease
Interventions: Active Comparator: Active tDCS and Active TUS, Sham Comparator: Sham TDCS and Sham TUS, Physical Therapy; Device · Other
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 40 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia Alzheimers, Dementia, Mild, Dementia, Alzheimer Type, Dementia of Alzheimer Type, Dementia, Cognitive Impairment, Mild, Cognitive Decline
Interventions: GammaSense Stimulation System (Active Settings), GammaSense Stimulation System (Sham Settings); Device
Lead sponsor: Cognito Therapeutics, Inc.; Industry
Eligibility: 55 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 5
States / cities: Delray Beach, Florida • Stuart, Florida • Methuen, Massachusetts + 2 more

Conditions: Childbirth
Interventions: Materna Prep Device, Sham Control; Device
Lead sponsor: Materna Medical; Industry
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Mountain View, California

Conditions: Migraine With Aura
Interventions: Partial Rebreathing Device, Sham breathing device; Device
Lead sponsor: Rehaler; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 9
States / cities: Palo Alto, California • Pasadena, California • Riverside, California + 6 more

Conditions: Huntington Disease
Interventions: Transcranial direct current stimulation (tDCS), Sham tDCS; Device
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 85 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: PTSD, Anxiety, Trauma, Sleep Disorders
Interventions: EEG biofeedback; Device
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Diego, California

Conditions: Neuropathy
Interventions: Scrambler Therapy, Sham Therapy; Device
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hemiparetic Stroke
Interventions: High-definition transcranial direct stimulation: sham, High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy; Device · Behavioral
Lead sponsor: Carle Foundation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Stress Incontinence Female, Urinary Incontinence, Urinary Incontinence,Stress, Pain, Pain Acute
Interventions: TENS, Control TENS; Procedure
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Acute Ischemic Stroke
Interventions: transcutaneous auricular vagal nerve stimulation, Sham transcutaneous vagal nerve stimulation; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Opioid-Related Disorders, Opioid Dependence, Opioid Addiction, Opioid Withdrawal
Interventions: Bridge Device, Lofexidine, Placebo, Sham Bridge Device; Device · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obstructive Sleep Apnea
Interventions: Upper Airway Muscle Exercise, Sham Exercise; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 79 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Spinal Cord Injuries, Spinal Cord Diseases
Interventions: Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Sham Non Invasive Spinal Cord Stimulation + Gait Training; Device · Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Vertigo, BPPV, Meniere Disease, Labrynthitis, Vestibular Disorder, Vestibular Migraine, Benign Paroxysmal Positional Vertigo, Ménière's Vertigo, Migraine Associated Vertigo, Uncompensated Unilateral Vestibulopathy
Interventions: Otoband Experimental, Otoband Sham; Device
Lead sponsor: Otolith Labs; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Alzheimer Disease, Family Members
Interventions: GENUS; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 55 Years to 90 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Lumbar Spine Stenosis Central Canal
Interventions: Percutaneous Lumbar Decompression, Sham lumbar decompression; Device
Lead sponsor: Napa Pain Institute; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Napa, California

Search by objective public record fields.

Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression

DB RCT for Specialized Phototherapy in Parkinson's Disease.

Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder

Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP)

Selective Nerve Stimulation (SNS) Pilot Study

Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression

Nicotine Withdrawal Symptoms and Smoking Relapse

Treatment of Androgenetic Alopecia in Females, 12 Beam

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.

Multi-Center Study of Sensory Stimulation to Improve Brain Function

A Clinical Phase II Study of the Materna Device to Shorten Delivery Time During Childbirth

PArtial REbreathing for Migraine With Aura 1

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

EEG Biofeedback Therapy as an Adjunct Treatment for PTSD

Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy

Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments

TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence.

Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct

An Innovative Intervention for OUD Treatment

Effects of Upper Airway Muscle Training on OSA

SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training

Treating the Symptoms of Vertigo in a Real-world Setting Using the OtoBand

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

Comparative Study of Sham Versus Mild® Procedure in Patients Diagnosed With Symptomatic Lumbar Central Canal Stenosis