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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 817–840 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Diabetic Neuropathies, Chronic Pain
Interventions: Active Comparator: Active tDCS + Active TUS, Sham; Device
Lead sponsor: Case Western Reserve University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 2
States / cities: Chicago, Illinois • Cleveland, Ohio

Conditions: Chronic Pain, Carpal Tunnel Syndrome
Interventions: transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Emphysema, COPD
Interventions: IBV® Valve System; Device
Lead sponsor: Olympus Corporation of the Americas; Industry
Eligibility: 40 Years to 74 Years
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2017
U.S. locations: 34
States / cities: Birmingham, Alabama • Los Angeles, California • Mission Viejo, California + 29 more

Conditions: Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction
Interventions: NightWare, Sham NightWare; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 22 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Chronotropic Incompetence
Interventions: Blended Sensor Optimization (BSO), Accelerometer Alone (AA); Device
Lead sponsor: Vivek Reddy; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF), Uterine Fibroids, Pelvic Pain, Pain Management
Interventions: TUNES (Transmucosal Uterosacral Electrical Stimulation), Sham TUNES Device; Device
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 28 Years to 52 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Spinal Cord Injury (SCI)
Interventions: Daily AIH Block, Sham dAIH Block, Respiratory Strength Training Block, AIH + Strength Training Block; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 70 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Spinal Cord Injuries
Interventions: Transcutaneous Spinal Cord Stimulation, Arm-crank bike exercise, Sham Stimulation; Device · Behavioral · Other
Lead sponsor: University of Washington; Other
Eligibility: 21 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Dyslexia
Interventions: active taVNS, sham taVNS; Device
Lead sponsor: University of Florida; Other
Eligibility: 10 Years to 12 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Pain
Interventions: anodal tDCS, cathodal tDCS, sham tDCS; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Obsessive Compulsive Disorder
Interventions: Low Intensity Focused Ultrasound, Sham (No Treatment); Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 22 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Abortion in First Trimester
Interventions: high frequency TENS treatment, Sham TENS treatment; Device
Lead sponsor: Planned Parenthood of Greater New York; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: Traditional Attention Bias Modification, Gamified Attention Bias Modification, Sham Attention Bias Modification; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Fibromyalgia
Interventions: RINCE; Device
Lead sponsor: Cerephex Corporation; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Pontiac, Michigan

Conditions: Alcohol Use Disorder, Addiction
Interventions: TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training; Device · Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Primary Focal Hyperhidrosis, Axilla
Interventions: DTS-G2 System, DTS System (Sham treatment); Device
Lead sponsor: Miramar Labs; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 7
States / cities: Sacramento, California • San Diego, California • Sunnyvale, California + 4 more

Conditions: Meibomian Gland Dysfunction, Dry Eye
Interventions: LipiFlow, Light Based (Sham) Treatment; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Interventions: ICE Condition, Sham Condition; Device
Lead sponsor: Liberating Technologies, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Holliston, Massachusetts • Minneapolis, Minnesota

Conditions: Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions: Low-level laser therapy; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Mild Cognitive Impairment
Interventions: Transcutaneous vagal nerve stimulation, Sham stimulation; Device
Lead sponsor: University of Florida; Other
Eligibility: 60 Years to 89 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: Gainesville, Florida

Conditions: Neurosciences, Substance-Related Disorders, Behavior Problem
Interventions: Placebo TMS Sham, Marinol 10Mg Capsule TMS Sham, Marinol 30Mg Capsule TMS Sham, Placebo TMS Real, Marinol 10Mg Capsule TMS Real, Marinol 30Mg Capsule TMS Real; Device · Drug · Other
Lead sponsor: Michael J. Wesley, PhD; Other
Eligibility: 18 Years to 34 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Aging
Interventions: Transcutaneous vagal nerve stimulation (tVNS), Cognitive training; Device · Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 90 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Tucson, Arizona • Gainesville, Florida

Conditions: Opioid Use Disorder
Interventions: Bridge™ active device, Bridge™ sham device; Device
Lead sponsor: Masimo Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Wernersville, Pennsylvania

Conditions: Head and Neck Cancer, Lymphedema of the Head and Neck
Interventions: LTU-904 Portable Laser Therapy Unit (active laser device), LTU-904 Portable Laser Therapy Unit (sham/inactive laser device); Device
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Nashville, Tennessee

Search by objective public record fields.

Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema

NightWare and Cardiovascular Health in Adults With PTSD

The Effect of Blended Sensor Efficiency on Relieving the Heart's Inability to Increase Its Rate During Exercise

Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief

FLO2 for Recovery After SCI

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

taVNS for Letter Learning in Dyslexia

Effects of Transcranial Direct Current Stimulation on Pain Perception

SONATA LIFU for OCD

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

Confirmatory Efficacy Trial of Attention Bias Modification for Depression

Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - St. Joseph Mercy Oakland

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

Efficacy and Safety of the DTS-G2 System in Patients With Axillary Hyperhidrosis

Meibomian Gland Dysfunction Treatment

Socket Cooling Effectiveness Take Home Study

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

Treatment of Mild Cognitive Impairment With Transcutaneous Vagal Nerve Stimulation

Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults

Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

Impact of Bridge™ Device to Treat Opioid Withdrawal Symptoms

Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema