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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 865–888 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Plantar Fascitis
Interventions: Photobiomodulation Therapy (PBMT), Sham-Photobiomodualtion Therapy (Sham-PBMT); Device
Lead sponsor: The Geneva Foundation; Other
Eligibility: 18 Years to 64 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Fibromyalgia
Interventions: RINCE; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Self Harm, Suicidal Ideation
Interventions: tVNS Program, Phone App Program, tVNS and Phone App Program, Sham tNVS and Control App; Device · Other · Combination Product
Lead sponsor: University of Notre Dame; Other
Eligibility: 13 Years to 17 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: South Bend, Indiana • Rochester, New York

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: HEPA portable air filter, Sham Control/Active Comparator; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 40 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Effect of tDCS on Memory in Older and Younger Adults
Interventions: Active tDCS, Sham tDCS; Device
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 75 Years
Enrollment: 271 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Non-arteritic Anterior Ischemic Optic Neuropathy (NAION), Trauma, Multiple Sclerosis (MS)
Interventions: Transcorneal Electrical Stimulation, Sham; Device
Lead sponsor: Wills Eye; Other
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Muscle Weakness
Interventions: Neuromuscular electrical Stimulation (NMES), Sham Stimulation; Device
Lead sponsor: RML Specialty Hospital; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Hinsdale, Illinois

Conditions: Total Knee Arthroplasty
Interventions: NEUROCUPLE™ Patch, Placebo Patch; Device
Lead sponsor: nCap Medical; Industry
Eligibility: 18 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Knee Injuries
Interventions: Biofeedback Knee Sleeve, Sham Biofeedback; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 12 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Spinal Cord Injury, Tetraplegia
Interventions: transcranial direct current stimulation, peripheral nerve somatosensory stimulation, sham transcranial direct current stimulation; Other
Lead sponsor: Shepherd Center, Atlanta GA; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Coronavirus, Covid19
Interventions: Soterix taVNS model 0125-LTE Stimulator - Active-Active Group, Soterix taVNS model 0125-LTE Stimulator - Sham-Active Group; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Post-treatment Lyme Disease Syndrome, Chronic Pain
Interventions: Sana Pain Reliever, Sham SPR; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Cognitive Aging, Alzheimer Disease, Protection Against
Interventions: Active NIR-PBM, Sham NIR-PBM; Device
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 89 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 2
States / cities: Tucson, Arizona • Gainesville, Florida

Conditions: Migraine
Interventions: CEFALY Active, CEFALY Placebo; Device
Lead sponsor: Cefaly Technology; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: New Haven, Connecticut • Lenexa, Kansas • New York, New York

Conditions: PTSD, Post Traumatic Stress Disorder
Interventions: Active VNS stimulation, Sham VNS stimulation; Device
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 22 Years to 79 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 3
States / cities: Austin, Texas • Dallas, Texas • Richardson, Texas

Conditions: Spinal Cord Injuries
Interventions: Acute Intermitted Hypoxia, Massed Practise, Rapael Glove; Other · Procedure
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 75 Years
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 3
States / cities: Chicago, Illinois • East Hanover, New Jersey

Conditions: Brain Injuries, Traumatic
Interventions: Balance and Gait Training using neurostimulation modulation., Sham Device; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Parkinson Disease
Interventions: Gen0Bh Transcranial Focused Ultrasound System (Active), Gen0Bh Transcranial Focused Ultrasound System (Sham); Device
Lead sponsor: Sanmai Technologies PBC dba Sanmai; Industry
Eligibility: 22 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Tucson, Arizona • Santa Monica, California • Gainesville, Florida + 1 more

Conditions: Atrial Fibrillation
Interventions: Parasym, Sham stimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 21 Years to 90 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Opioid-use Disorder, Opioid Dependence, Opioid Abuse
Interventions: Transcranial Direct Current Stimulation (tDCS); Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders
Interventions: Repetitive Transcranial Magnetic Stimulation, Repetitive Transcranial Magnetic Stimulation (Intermittent Theta Burst Stimulation), Repetitive Transcranial Magnetic Stimulation (Sham); Device
Lead sponsor: Centre for Addiction and Mental Health; Other
Eligibility: 18 Years to 55 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Catonsville, Maryland • Manhasset, New York

Conditions: Parkinson's Disease (PD)
Interventions: Shame Control (Baseline), Standard of Care Deep Brain Stimulation, Illumina 3D Deep Brain Stimulation, Illumina 3D Deep Brain Stimulation Reduced Amplitude, Illumina 3D Deep Brain Stimulation Higher Amplitude; Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Traumatic Brain Injury
Interventions: Transcranial photobiomodulator (tPBM), Transcranial photobiomodulator (tPBM) in sham mode; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 55 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Fibromyalgia, Pain
Interventions: Transauricular vagus nerve stimulation (taVNS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Search by objective public record fields.

Low-Level Laser Therapy for Plantar Fasciitis

A Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - University of Michigan

Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents

Indoor Air Quality and Respiratory Symptoms in Former Smokers

Effect of Noninvasive Electrical Brain Stimulation on Memory at Different Times of Day in Younger and Older Adults

Electric Stimulation of the Eye to Improve Vision After Trauma

Facilitating Functional Independence in Patients Receiving Prolonged Mechanical Ventilation

NEUROCUPLE™ in TKA Patients to Enhance Pain Management

AI Driven Biofeedback Wearable

Conditioning Neural Circuits to Improve Upper Extremity Function

NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis

Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Acute Treatment of Migraine With e-TNS

Targeted Plasticity Therapy for PTSD

A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury

Noninvasive Neuromodulation for Treatment of Symptoms Due to Mild or Moderate Traumatic Brain Injury

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

Synaptic Plasticity in the Epicardial Ganglionated Plexi

Neuromodulation and Cognitive Training in Opioid Use Disorder

Neuromodulation of Social Cognitive Circuitry in People With Schizophrenia Spectrum Disorders

Automated Image-Guided Programming of Deep Brain Stimulation (DBS) for Parkinson's Disease

tPBM in Older Adults With Traumatic Brain Injury

Effects of taVNS on Fibromyalgia Pain