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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 913–936 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Postoperative Pain
Interventions: Placebo comparator: VR googles and the non reality experience, Active Comparator: VR googles and the real VR program to enter act with and experience; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Suicidal Ideation, Major Depressive Disorder
Interventions: MagVenture TMS Therapy System w/Theta Burst Stimulation, Sham MagVenture TMS Therapy System w/Theta Burst Stimulation; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 12 Years to 18 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Traumatic Brain Injury
Interventions: rTMS, Sham rTMS; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 20 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Opioid Withdrawal, Opioid Use Disorder (OUD)
Interventions: Sparrow Link (Active tAN), Sparrow Link (Sham tAN); Device
Lead sponsor: Payel Roy; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Healthy
Interventions: Anodal speech motor tDCS, Cathodal speech motor tDCS, Anodal IFG tDCS, Cathodal IFG tDCS, Sham tDCS; Device
Lead sponsor: New York University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Overactive Bladder
Interventions: Active TENS, Sham TENS; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Major Depressive Disorder
Interventions: Repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: Neuronetics; Other
Eligibility: 18 Years to 70 Years
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 13
States / cities: Poway, California • Stanford, California • Chicago, Illinois + 9 more

Conditions: Osteoarthritis, Degenerative
Interventions: Pulsed Low Intensity Ultrasound, Sham Comparator; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 3
States / cities: San Diego, California • Dallas, Texas • Salt Lake City, Utah

Conditions: Hearing Loss, Noise-Induced
Interventions: Near Infrared Light, Noise Stimulus, Sham Near Infrared Light; Device · Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 45 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Fort Rucker, Alabama • Miami, Florida • Wright-Patterson Air Force Base, Ohio

Conditions: Stress Disorders, Post-Traumatic
Interventions: Magnetic EEG/ECG-guided Resonance Therapy, Sham; Device
Lead sponsor: Wave Neuroscience; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Nicotine Dependence, Cigarettes
Interventions: Fully Active, LLLT Only, Music Only, Placebo; Device
Lead sponsor: Freedom Laser, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Mendham, New Jersey

Conditions: Type 2 Diabetes, Obesity
Interventions: EndoBarrier, Sham Procedure; Device · Procedure
Lead sponsor: Morphic Medical Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 25
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 20 more

Conditions: Macular Telangiectasia
Interventions: 577-nm PASCAL laser; Device
Lead sponsor: The Lowy Medical Research Institute Limited; Other
Eligibility: 21 Years to 79 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Knee Osteoarthritis, Depression
Interventions: repetetive transcranial magnetic stimulation; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years to 95 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid Use Disorder, Chronic Pain, Anxiety Disorder
Interventions: Low-Intensity Focused Ultrasound, Low-Intensity Focused Ultrasound - sham; Device
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Stress Urinary Incontinence
Interventions: BTL Emsella, Sham BTL Emsella; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 80 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Exocrine Pancreatic Insufficiency
Interventions: RELiZORB, Placebo; Device
Lead sponsor: Alcresta Therapeutics, Inc.; Industry
Eligibility: 4 Years to 45 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 11
States / cities: Los Angeles, California • Boise, Idaho • Indianapolis, Indiana + 8 more

Conditions: Gastroesophageal Reflux Disease
Interventions: Gatekeeper Reflux Repair System; Device
Lead sponsor: MedtronicNeuro; Industry
Eligibility: 18 Years and older
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 10
States / cities: San Francisco, California • Atlanta, Georgia • Chicago, Illinois + 7 more

Conditions: Glaucoma
Interventions: rtACS Stimulation, Sham Intervention; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 50 Years to 70 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Lower Back Pain
Interventions: Fischell Transcutaneous Magnetic Stimulation Pain Treatment Device, Placebo; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Spinal Cord Injuries
Interventions: Motor Skill Training, Transcranial direct current stimulation (tDCS); Other · Device
Lead sponsor: Shepherd Center, Atlanta GA; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Dry Eye Syndrome, Keratoconjunctivitis Sicca
Interventions: Oculeve Intranasal, Sham, Oculeve Extranasal; Device
Lead sponsor: Oculeve, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 2
States / cities: Waterbury, Connecticut • Norfolk, Virginia

Conditions: Concussion
Interventions: Laboratory testing, Blood and Urine Draws; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 18 Years to 25 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Peripheral Arterial Disease
Interventions: Therapeutic Device; Device
Lead sponsor: Vibrato Medical, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Orange, California

Search by objective public record fields.

Virtual Reality Distraction for Reduction

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

rTMS to Improve Cognitive Function in TBI

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning

TENS Used for Pain Management During Office Cystoscopy Botox Injections

Study of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive Disorder

A Pilot Trial to Assess Low-Intensity Ultrasound in Osteoarthritis

Noise Exposure and Near-Infrared Light

Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD

Evaluation of LLLT/Music for Smoking Cessation

Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese

MacTel Laser Study

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Low-Intensity Focused Ultrasound and the Complex Patient

BTL Emsella Chair Versus Sham for the Treatment of Stress Urinary Incontinence

Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)

An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)

A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma

Treatment of Back Pain Using Transcutaneous Magnetic Stimulation (TCMS)

Enhancing Corticospinal Activation for Improved Walking Function

A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome

Innovative Concussion Prevention Device

A Non-significant Risk Clinical Study to Assess Perfusion Changes With Application of a TUS for Patients With PAD