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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:09 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1009–1032 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Overactive Bladder, Urge Incontinence, Urinary Incontinence, Urinary Frequency More Than Once at Night
Interventions: Zida; Device
Lead sponsor: Exodus Innovations; Industry
Eligibility: 21 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Postoperative Complications, Plastic Surgery
Interventions: Photobiomodulation; Device
Lead sponsor: Elixir MD Inc; Industry
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Episodic Migraine
Interventions: Sham Treatment Location, Verum Treatment Location; Device
Lead sponsor: Theranova, L.L.C.; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: COPD
Interventions: PrO2, Threshold Inspiratory Muscle Trainer; Device
Lead sponsor: Miami VA Healthcare System; Federal
Eligibility: 40 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Spinal Cord Injuries
Interventions: AIH - Intermittent Hypoxia - hypoxia air mixture, SHAM - Intermittent Room Air - room air mixture, TESS - Transcutaneous Electrical Spinal Cord Stimulation + Functional Task Practice; Other · Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Diabetes Mellitus, Type 2, Obesity
Interventions: taVNS, Sham taVNS; Device
Lead sponsor: Burrell College of Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Las Cruces, New Mexico

Conditions: Traumatic Brain Injury
Interventions: Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Armeo training; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Episode, Borderline Personality Disorder, Suicide
Interventions: Intermittent Theta Burst Transcranial Magnetic Stimulation (Active), Intermittent Theta Burst Transcranial Magnetic Stimulation (Sham); Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Essential Tremor
Interventions: Cala ONE Device; Device
Lead sponsor: Cala Health, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 4
States / cities: San Francisco, California • Sunnyvale, California • Kansas City, Kansas + 1 more

Conditions: Osteoarthritis, Knee Pain
Interventions: "Kineticure System" followed by sham, sham followed by "Kineticure System"; Device
Lead sponsor: Kineticure; Industry
Eligibility: 45 Years to 80 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Neuropathy
Interventions: Infrared Phototherapy, Sham; Other
Lead sponsor: Healthlight, LLC; Industry
Eligibility: 25 Years to 90 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Topeka, Kansas

Conditions: Fibromyalgia
Interventions: Sana Sham Device; Device
Lead sponsor: Sana Health; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Breast Cancer, Colorectal Cancer
Interventions: Acupuncture using Seirin® needles, Sham Acupuncture using Park Sham placebo acupuncture device; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Vitamin D Deficiency, Vitamin D Insufficiency
Interventions: UVB treatment, Sham comparator; Device
Lead sponsor: Boston University; Other
Eligibility: 22 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Kidney Injury
Interventions: SBI-101, Sham; Biological · Device
Lead sponsor: Sentien Biotechnologies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Allentown, Pennsylvania

Conditions: Obstructive Sleep Apnea
Interventions: Respiratory muscle strength training, Sham respiratory muscle strength training; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Rheumatoid Arthritis (RA)
Interventions: Non-invasive ultrasound stimulation of the spleen - Treatment Setting 1, Non-invasive ultrasound stimulation of the spleen - Treatment Setting 2, Sham ultrasound stimulation (control), Conventional Synthetic DMARD; Device · Drug
Lead sponsor: SecondWave Systems Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 5
States / cities: Glendale, Arizona • Covina, California • Temecula, California + 2 more

Conditions: Inflammation
Interventions: Occipito-Atlantal Decompression (OA DC), Sham Occipito-Atlantal Decompression (Sham OA DC), Splenic Lymphatic Pump Technique (SpLPT), Sham Splenic Lymphatic Pump Technique (Sham SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS); Procedure · Device
Lead sponsor: Burrell College of Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Las Cruces, New Mexico

Conditions: Dysphagia
Interventions: Pharyngeal exerciser, sham pharyngeal exerciser; Device
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Upper Respiratory Infection
Interventions: SinuSonic Device, Sham SinuSonic Device; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Acute Migraine
Interventions: Nerivio Migra neurostimulation, Sham Nerivio Migra; Device
Lead sponsor: Theranica; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Albany, New York • Hartford, New York + 1 more

Conditions: Obsessive-Compulsive Disorder
Interventions: Stereoencephalography (SEEG), Deep Brain Stimulation (DBS); Device
Lead sponsor: Casey H. Halpern, M.D.; Other
Eligibility: 22 Years to 75 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 2
States / cities: Stanford, California • Philadelphia, Pennsylvania

Conditions: Multiple Sclerosis
Interventions: transcranial direct current stimulation; Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 70 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Tourette Syndrome
Interventions: NeuroPace RNS® System Deep Brain Stimulator; Device
Lead sponsor: University of Florida; Other
Eligibility: 25 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Search by objective public record fields.

Transcutaneous Tibial Nerve Stimulation: the ZIDA Device Equivalence

ELIXIR MDTM Satisfaction Clinical Trial

Evaluation of Peripheral Nerve Stimulation for Acute Treatment of Migraine Pain

Inspiratory Muscle Training in COPD

Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance

Transcranial Direct Current Stimulation (tDCS) and Motor Training for Traumatic Brain Injury (TBI) Survivors

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Cala ONE Device for Essential Tremor

Combined Vibrations, Passive Motion and Thermotherapy for Knee Osteoarthritis

Efficacy of Near Infrared Phototherapy in Type 2 Diabetic Neuropathy

Efficacy of Sana Treatment in Fibromyalgia

Acupuncture to Prevent Chemotherapy Dose Reduction Due to Chemotherapy-induced Peripheral Neuropathy in Breast and Colorectal Cancer Patients (GCC1232)

Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status

A Study of Cell Therapy for Subjects With Acute Kidney Injury Who Are Receiving Continuous Renal Replacement Therapy

Airway Muscle Training for Obstructive Sleep Apnea

At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

Anti-inflammatory Actions of Osteopathic Manipulative Treatment

External Pharyngeal Exerciser and Dysphagia

Use of Novel Sinusonic Device for Prevention of Community Acquired Upper Respiratory Infection (URI)

Migraine Treatment With Nerivio Migra Neurostimulation Device

SEEG-Guided DBS for OCD

tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple Sclerosis

Brain Stimulation for the Treatment of Tourette Syndrome