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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Migraine Headaches, Patent Foramen Ovale
Interventions: Sham Procedure, AMPLATZER PFO Occluder; Other · Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 230 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 30
States / cities: Phoenix, Arizona • Los Angeles, California • Colorado Springs, Colorado + 23 more

Conditions: Functional Disorder of Intestine, Nausea Persistent
Interventions: Neurostimulator, Sham; Device
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 11 Years to 18 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Stress Urinary Incontinence
Interventions: Transcutaneous electrical stimulation (Elitone); Device
Lead sponsor: Elidah, Inc.; Industry
Eligibility: 21 Years to 75 Years · Female only
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Monroe, Connecticut

Conditions: Holmium Laser Prostate Surgery, Radical Prostatectomy
Interventions: EMSELLA®, Sham Comparator Device; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 100 Years · Male only
Enrollment: 2,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
Interventions: Sham, Low dose tDCS, High dose tDCS, mCIMT; Device · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 11 more

Conditions: Muscle Spasticity, Stroke
Interventions: MyoRegulator® device; Device
Lead sponsor: PathMaker Neurosystems Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Cambridge, Massachusetts • Charlestown, Massachusetts

Conditions: Idiopathic Parkinson's Disease, Parkinson Disease, Depression
Interventions: Transcranial Direct Current Stimulation; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Post-Amputation Phantom Limb Pain
Interventions: Cryoneurolysis, Sham Comparator; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 6
States / cities: Palo Alto, California • San Diego, California • Gainesville, Florida + 2 more

Conditions: Cocaine Use Disorder (CUD)
Interventions: Low Intensity Focused Ultrasound; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Anxiety, Depression, Insomnia, Sleep Quality
Interventions: Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator); Device
Lead sponsor: Christina Murphey, RN, PhD; Individual
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Austin, Texas • Corpus Christi, Texas

Conditions: Nail Psoriasis
Interventions: 308 nm excimer laser, Sham laser; Device
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Major Depressive Disorder
Interventions: Active CES, Sham CES; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Rhinitis
Interventions: RhinAer Stylus, Sham; Device
Lead sponsor: Aerin Medical; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 13
States / cities: Roseville, California • Torrance, California • Plantation, Florida + 10 more

Conditions: Plaque Psoriasis
Interventions: Autonomic Nerve Modulation - Active, Autonomic Nerve Modulation - Control; Device
Lead sponsor: Thync Global, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Fremont, California

Conditions: Chemotherapy Induced Peripheral Neuropathy (CIPN)
Interventions: The Lilac Device, Sham device; Device
Lead sponsor: Luminate Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 17
States / cities: Poway, California • Norwich, Connecticut • Hialeah, Florida + 13 more

Conditions: Major Depressive Disorder \(MDD, Depressive Disorder, Major
Interventions: Active VeNS Device, Sham VeNS Device; Device
Lead sponsor: Neurovalens Ltd.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Diabetic Foot Ulcers
Interventions: Epiflo, Moist Wound Therapy; Device · Other
Lead sponsor: Neogenix, LLC dba Ogenix; Industry
Eligibility: 20 Years to 90 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 14
States / cities: Phoenix, Arizona • Tucson, Arizona • Encinitas, California + 11 more

Conditions: Fibromyalgia
Interventions: CES device, sham device; Device
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Treatment Resistant Depression
Interventions: Active TBS-DLPFC, Sham TBS-DLPFC; Device
Lead sponsor: Stanford University; Other
Eligibility: 22 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: Obstructive Sleep Apnea
Interventions: OSA LLLT treatment device, Sham Comparator; Device
Lead sponsor: Photonica USA, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 2
States / cities: Miami, Florida • Miramar, Florida

Conditions: Nerve Injury
Interventions: Temporary Peripheral Nerve Stimulation System, Sham Temporary Peripheral Nerve Stimulation System; Device
Lead sponsor: Epineuron Technologies Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 6
States / cities: Gainesville, Florida • Orlando, Florida • New Orleans, Louisiana + 3 more

Conditions: Smoking Cessation
Interventions: rTMS Active 20Hz, rTMS Sham; Device
Lead sponsor: The City College of New York; Other
Eligibility: 21 Years to 65 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Anxiety, Depression
Interventions: Alpha-Stim Active, Alpha-Stim Inactive; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Arthritis of the Knee
Interventions: iovera°, iovera° Sham; Device
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 22 Years to 79 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 8
States / cities: San Diego, California • Englewood, Colorado • Fort Lauderdale, Florida + 5 more

Search by objective public record fields.

PREMIUM Migraine Trial

Efficacy of Ear Neurostimulation for Adolescents With Functional Abdominal Pain

Stress Incontinence Trial With Elitone Device

HIFEM Technology for Post-Radical Prostatectomy and Post-Holmium Laser Prostate Surgery

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity

Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation

Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study

Low Intensity Focused Ultrasound in Cocaine Use Disorder

Efficacy of CES in New Mothers During the Post Partum Period

308nm Excimer Laser for Treatment of Fingernail Psoriasis

Efficacy and Safety of Cranial Electrical Stimulation (CES) for Major Depressive Disorder (MDD)

RhinAer Procedure for Treatment of Chronic Rhinitis Study

Efficacy and Safety Study of Autonomic Nerve Modulation (ANM) in Subjects With Moderate Plaque Psoriasis

The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study

Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)

Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

Rapid Acting Transcranial Magnetic Stimulation

Alesis OSA-1 Obstructive Sleep Apnea Treatment

Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation

Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation

Effectiveness of CES on Emotional and Cellular Wellbeing

A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated With Total Knee Arthroplasty