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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Shockwave therapy device Clear all
Recruiting Not applicable Interventional

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

NCT07062471
View directory record Official record
Conditions
Carotid Artery Calcification, Carotid Artery Diseases
Interventions
Carotid Intravascular Lithotripsy (IVL)
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
25
States / cities
Little Rock, Arkansas • Rancho Mirage, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Not yet recruiting Not applicable Interventional

Clinical Outcomes of Focused Shockwave Therapy Without Adjunct Rehabilitation Compared to Standard Physical Rehabilitation in Patients With Grade I-III Knee Osteoarthritis: A Single-Blind Randomized Study

NCT07567365
View directory record Official record
Conditions
Knee Osteoarthristis
Interventions
Physical Rehab, Focused Shockwave Therapy
Other · Device
Lead sponsor
Pulse Wave USA
Industry
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Westminster, Colorado
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction

NCT04136288
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
MoreNova
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 55 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Phase 3 Interventional

Study of Effectiveness and Safety of Extracorporeal Shock Wave Therapy (ESWT) for Treatment of Painful Heel Syndrome

NCT00720694
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
Duolith SD1, Sham Duolith SD1
Device
Lead sponsor
Storz Medical AG
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
6
States / cities
Palo Alto, California • Hamden, Connecticut • Newtown, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 5, 2026, 10:52 PM EDT
Terminated Not applicable Interventional

Dornier Aries 2 Extracorporeal Shock Wave Device for the Treatment of Mild Erectile Dysfunction (ED)

NCT03039218
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Dornier Aries 2, Placebo / Sham
Device
Lead sponsor
Dornier MedTech Systems
Industry
Eligibility
22 Years to 70 Years · Male only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
San Diego, California • Omaha, Nebraska • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Sham-Controlled Prospective Study Characterizing Erectile Tissue Ultrasound Changes Resulting From Penile LiSWT

NCT06600893
View directory record Official record
Conditions
Erectile Dysfunctions
Interventions
Low intensity shockwave therapy (LiSWT), Sham
Device
Lead sponsor
San Diego Sexual Medicine
Other
Eligibility
21 Years to 80 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

A Single Arm Study of Extracorporeal Shockwave Therapy for Management of Erectile Dysfunction

NCT07592533
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Shockwave therapy
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Comparison of Lithotripsy Urolithiasis Machines

NCT04069338
View directory record Official record
Conditions
Kidney Stone, Kidney Calculi, Ureteral Calculi, Ureterolithiasis, Urolithiasis
Interventions
Lithotripter
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

NCT06686680
View directory record Official record
Conditions
Knee Osteoarthristis, ACL Injuries, Post-Traumatic
Interventions
extracorporeal shockwave therapy (ESWT), Sham Comparator
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 5, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional

Shockwave Therapy for Plantar Fasciitis RCT

NCT04332471
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Radial shockwave therapy, Focused shockwave therapy, Shockwave therapy device, Home therapy
Procedure · Device · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 100 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Phase 3 Interventional Results available

Effectiveness of dermaPACE™ Device and Standard Treatment Compared to Standard Treatment Alone for Diabetic Foot Ulcers

NCT00536744
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
acoustical pulse energy (extracorporeal shockwave), Sham
Device · Other
Lead sponsor
SANUWAVE, Inc.
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
21
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

NCT05102019
View directory record Official record
Conditions
Refractory Angina
Interventions
Arm 1: treatment with Shockwave Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry
Device · Other
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
71
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

NCT05432999
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle, Spastic Paraplegia, Spastic Quadriplegia, Spastic Tetraplegia, Paraplegia, Tetraplegia
Interventions
Extracorporeal Shockwave Therapy
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Changes in Penile Firmness With Low-Intensity Shockwave Therapy (LiST)

NCT05756803
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Low-intensity acoustic shockwave therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Great Neck, New York • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment

NCT07000045
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Calcification
Interventions
Intravascular lithotripsy, Rotational atherectomy
Device
Lead sponsor
Annapoorna Kini
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional

LiSWT for Nerve Sparing Radical Prostatectomy ED

NCT05877144
View directory record Official record
Conditions
Erectile Dysfunction, Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
Interventions
Nerve-Sparing Prostatectomy, Medical Device Usage and Evaluation, Duplex Ultrasound, Survey Administration, Sham Intervention
Procedure · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

FORWARD PAD IDE Study With the Shockwave Javelin IVL Catheter

NCT05858905
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Intravascular Lithotripsy
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
21
States / cities
Palo Alto, California • Thornton, Colorado • Bradenton, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Suspended Phase 1Phase 2 Interventional

High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain

NCT00637364
View directory record Official record
Conditions
Pain, Pancreatic Adenocarcinoma, Ductal Adenocarcinoma
Interventions
High intensity focused ultrasound, HIFU
Procedure
Lead sponsor
CMED HIFU Development Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2009 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Extracorporeal Shockwave Therapy (ESWT) for the Management of Stress Fractures and High-grade Bone Stress Injuries (BSIs)

NCT06609265
View directory record Official record
Conditions
Bones Stress Injury, Bone Stress Fracture
Interventions
Extracorporeal shockwave treatment (ESWT)., Sham Device
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Los Angeles, California • Stanford, California • Cambridge, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Not yet recruiting Not applicable Interventional

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Femoral Stenting (SKYWARD Trans-Femoral IDE [Investigational Device Exemption] Study)

NCT07512128
View directory record Official record
Conditions
Carotid Artery Calcification, Carotid Artery Diseases
Interventions
Carotid Intravascular Lithotripsy
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
25
States / cities
Scottsdale, Arizona • Aurora, Colorado • Jacksonville, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Low Intensity Shockwave for the Treatment of Erectile Dysfunction

NCT03067987
View directory record Official record
Conditions
Vasculogenic Erectile Dysfunction
Interventions
Low Intensity Linear Shockwave Device for the Treatment of Erectile Dysfunction.
Device
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 80 Years · Male only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Prospective Assessment of Integrative Therapies for Neuromusculoskeletal Pain (PAIN)

NCT07094282
View directory record Official record
Conditions
Chronic Pain
Interventions
Acupuncture, myofascial therapy, microcurrent therapy, LASER, extracorporeal shockwave therapy, Pulsed electromagnetic therapies, Miscellaneous integrative medicine
Other
Lead sponsor
David Moss
Federal
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Post-Market Clinical Follow Up Study to Collect Additional Data and Imaging

NCT04880070
View directory record Official record
Conditions
Connective Tissue Defect
Interventions
Shockwave Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

NCT02923193
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Shockwave Lithoplasty® Peripheral Lithoplasty System, Medtronic IN.PACT (DCB)
Device · Drug
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
40
States / cities
Little Rock, Arkansas • Palo Alto, California • Aurora, Colorado + 33 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 5, 2026, 10:52 PM EDT