- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea, Sleep-Disordered Breathing
- Interventions
- Methadone, Fentanyl/Hydromorphone
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 3 Years to 17 Years
- Enrollment
- 440 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
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- Conditions
- Postoperative Pain, Recovery
- Interventions
- Intravenous Methadone, Short-acting Opioids Intraoperative analgesia
- Drug
- Lead sponsor
- Alexandre P. Joosten
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Irvine, California
- Conditions
- Arthroscopic Knee Repair, Arthroscopic Hip Repair
- Interventions
- Methadone group, Placebo
- Drug
- Lead sponsor
- Keck School of Medicine of USC
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Los Angeles, California