Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 9, 2026, 12:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 136 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Silicone hydrogel contact lenses Clear all
Completed Not applicable Interventional Results available

Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens

NCT04631796
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Multipurpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
Orlando, Florida • Bloomington, Illinois • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses

NCT00382902
View directory record Official record
Conditions
Contact Lens Care
Interventions
OptiFree Multi-Purpose Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Study of ACUVUE® ADVANCE® PLUS Contact Lenses.

NCT01244893
View directory record Official record
Conditions
Myopia
Interventions
Acuvue Advance Plus prePQ, Acuvue Advance Plus postPQ
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
3
States / cities
Powell, Ohio • Warwick, Rhode Island • Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients

NCT00799422
View directory record Official record
Conditions
Conjunctival Staining
Interventions
Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2012 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression

NCT01423773
View directory record Official record
Conditions
Ocular Comfort
Interventions
Lotrafilcon A test contact lens, Lotrafilcon A control contact lens, Ultra-High Resolution Optical Coherence Tomographer (OCT)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2013 · Synced Oct 9, 2026, 12:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Performance of Verofilcon A Toric Contact Lenses

NCT07586982
View directory record Official record
Conditions
Contact Lenses, Presbyopia
Interventions
Total 30 multi foric contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a New Silicone Hydrogel Contact Lens

NCT01873846
View directory record Official record
Conditions
Myopia
Interventions
Silicone Hydrogel Contact Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 35 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Madison, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional

Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses

NCT04254003
View directory record Official record
Conditions
Refractive Errors
Interventions
DT1 Toric contact lenses, AO1DfA contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Maitland, Florida • Eden Prairie, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens

NCT04702984
View directory record Official record
Conditions
Refractive Errors
Interventions
LID021201 contact lenses, OPTI-FREE multipurpose solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
3
States / cities
Maitland, Florida • Memphis, Tennessee • Wichita Falls, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
View directory record Official record
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Oct 9, 2026, 12:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessing Patient Comfort With Two Different Multi-Purpose Disinfecting Solutions

NCT01847105
View directory record Official record
Conditions
Contact Lens Solution Toxicity
Interventions
RevitaLens, OptiFree PureMoist
Other
Lead sponsor
Hom, Milton M., OD, FAAO
Individual
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Azusa, California • Morrow, Georgia • Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daily Disposable Dispensing Clinical Trial of Test Lens Against Stenfilcon A Lens

NCT03024970
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A lens with solution additive (test), stenfilcon A lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a HYDRAGLYDE® Regimen

NCT03026257
View directory record Official record
Conditions
Refractive Errors, Myopia, Hypermetropia
Interventions
Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent, Hydrogen peroxide-based contact lens solution with added wetting agent, Senofilcon C contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Habitual Multi-Purpose Solution (HMPS)
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Pilot Dispensing Evaluation of a Plus Power Lens

NCT01228591
View directory record Official record
Conditions
Hyperopia
Interventions
Acuvue Advance Plus, Acuvue Advance
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
3
States / cities
Winter Park, Florida • New York, New York • Nanticoke, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PAVES Benchmarking Pilot Study of Daily Disposable Contact Lenses

NCT04032457
View directory record Official record
Conditions
Refractive Errors
Interventions
Phase A - olifilcon B with Tangible Coatings, Phase B - etafilcon A with Tangible Coatings
Device
Lead sponsor
Vision Service Plan
Industry
Eligibility
18 Years to 42 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Atlanta, Georgia • Niles, Illinois • Carmel, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses

NCT04980456
View directory record Official record
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
14
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2023 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
View directory record Official record
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2020 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 9, 2026, 12:02 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of DW Silicone Hydrogel Lens Compared to DW Silicone Hydrogel Lens

NCT01386008
View directory record Official record
Conditions
Myopia
Interventions
senfilcon A contact lens, investigational enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 9, 2026, 12:02 PM EDT
Completed No phase listed Observational

Air Optix Extended Wear Contact Lenses

NCT05886881
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive, Comfilcon A spherical soft contact lenses, Comfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses

NCT05805059
View directory record Official record
Conditions
Myopia
Interventions
Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Ocoee, Florida • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Central Corneal Swelling With Silicone Hydrogel Materials

NCT02328937
View directory record Official record
Conditions
Corneal Swelling
Interventions
etafilcon A, lotrafilcon B, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 9, 2026, 12:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT05933772
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Pittsburg, Kansas • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 9, 2026, 12:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Longitudinal Evaluation of Silicone Hydrogel (LASH) Study

NCT00727402
View directory record Official record
Conditions
Corneal Infiltrates
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
15 Years and older
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2012 · Synced Oct 9, 2026, 12:02 PM EDT