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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Single Vision Soft Contact Lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

NCT03585790
View directory record Official record
Conditions
Asthenopia, Myopia
Interventions
Contact lens with Multifocal Optics, Contact lens with Single Vision Optics
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens

NCT03920280
View directory record Official record
Conditions
Refractive Errors
Interventions
LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pensacola, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Sep 3, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
View directory record Official record
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 3, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wavelength Intervention for Nearsighted Kids

NCT06598423
View directory record Official record
Conditions
Myopia
Interventions
Specialized soft contact lens 1, Specialized soft contact lens 2
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)

NCT00733291
View directory record Official record
Conditions
Myopia
Interventions
Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2011 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of an Investigational Soft Contact Lens

NCT01254747
View directory record Official record
Conditions
Myopia
Interventions
Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus), Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
Not listed
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Duluth, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2012 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression

NCT01423773
View directory record Official record
Conditions
Ocular Comfort
Interventions
Lotrafilcon A test contact lens, Lotrafilcon A control contact lens, Ultra-High Resolution Optical Coherence Tomographer (OCT)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Orthokeratology in Myopia Control

NCT03465748
View directory record Official record
Conditions
Myopia
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 13 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 3, 2026, 5:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Contact Lens and Myopia Control in Optometry School Students

NCT04334369
View directory record Official record
Conditions
Myopia, Progressive
Interventions
Proclear Single Vision Contact Lenses manufactured by CooperVision, Proclear Multifocal Contact Lenses manufactured by CooperVision
Device
Lead sponsor
Jeff Rabin
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

NCT05483127
View directory record Official record
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 3, 2026, 5:15 AM EDT
Suspended No phase listed Observational

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

NCT04838223
View directory record Official record
Conditions
Dry Eye, Neuropathic Pain
Interventions
Hyperosmolar Response, Proparacaine Challenge Test, Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Optional; only for Contact Lens Wearers, Ocular Pain Assessment Survey (OPAS), Visual Analogue Questionnaire
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
16
States / cities
Azusa, California • Pomona, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 3, 2026, 5:15 AM EDT
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
View directory record Official record
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 3, 2026, 5:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optical Defocus to Stimulate Eye Elongation in Hyperopia

NCT00950924
View directory record Official record
Conditions
Hyperopia, Refractive Error
Interventions
Simultaneous Vision Bifocal Soft Contact Lenses, Single Vision Soft Contact Lenses
Device
Lead sponsor
Aller, Thomas A., OD
Other
Eligibility
5 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)

NCT06698731
View directory record Official record
Conditions
Presbyopia Condition
Interventions
Test lens, Control lens
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
45 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

NCT04534517
View directory record Official record
Conditions
Visual Acuity
Interventions
JJV Investigational Multifocal Contact Lens, ACUVUE OASYS® with HYDRACLEAR® PLUS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
11
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Contact Lens Optics and Visual Performance

NCT05308069
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lens, Multifocal contact lens
Device
Lead sponsor
David A Berntsen, OD PhD
Other
Eligibility
18 Years to 39 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Sep 3, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control

NCT04080128
View directory record Official record
Conditions
Myopia
Interventions
Contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 3, 2026, 5:15 AM EDT
Not yet recruiting Not applicable Interventional

Contact Lenses to Slow Myopia Progression in Adults

NCT07747311
View directory record Official record
Conditions
Myopia, Myopia Progression
Interventions
Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 30 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 3, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)

NCT04807361
View directory record Official record
Conditions
Accomodation, Biofeedback Training, Myopia
Interventions
Auditory biofeedback traing
Behavioral
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 15 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Long Beach, New York
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Evaluating Contact Lens Optics

NCT05028790
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lens, Multifocal contact lens
Device
Lead sponsor
David A Berntsen, OD PhD
Other
Eligibility
18 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 3, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Toric/Spherical Single Vision Contact Lens

NCT03970512
View directory record Official record
Conditions
Refractive Errors
Interventions
Apioc-A and Apioc-S Contact Lenses
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
18 Years to 35 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Athens, Ohio • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 3, 2026, 5:15 AM EDT