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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sitting breaks Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Sedentary Behavior Interventions to Affect Acute Physiological Changes

NCT02544867
View directory record Official record
Conditions
Sedentary Behavior
Interventions
Sedentary behavior
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2015 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking Sitting with High-intensity Interval Training for Brain Health

NCT06243016
View directory record Official record
Conditions
Aging
Interventions
High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior and Health Outcomes Study

NCT03153930
View directory record Official record
Conditions
Sedentary Lifestyle, Metabolic Disturbance, Pediatric Obesity, Physical Activity
Interventions
Walking breaks, Sitting only
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
11 Years to 16 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Phase 2 Interventional

Sit Less, Interact and Move More (SLIMM) 2 Study

NCT05173714
View directory record Official record
Conditions
Chronic Kidney Diseases, Obesity
Interventions
SLIMM, Standard Resistance Training, Guided Resistance Training, Placebo, Semaglutide
Behavioral · Drug
Lead sponsor
Srinvasan Beddhu
Other
Eligibility
20 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Stanford, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment

NCT04715711
View directory record Official record
Conditions
Hyperthermia
Interventions
Forearm coolng, Wet-towel cooling, mist-fan, passive cooling
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 28 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sit Less for Successful Aging

NCT03537677
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Reduction in Sedentary Behavior
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 24, 2018 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Vibro-tactile Stimulation Intensity on Head Posture in Cervical Dystonia

NCT07245615
View directory record Official record
Conditions
Cervical Dystonia
Interventions
cervical vibrotactile stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of ICE on Exercise Performance in the Heat

NCT04596618
View directory record Official record
Conditions
Hyperthermia
Interventions
Forearm cooling
Device
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 20, 2020 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interrupting Sitting Time During Postprandial State

NCT04590729
View directory record Official record
Conditions
Sedentary Behavior
Interventions
3-min Exercise Per 30 Min, 3-min Exercise Per 15 Min
Behavioral
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 45 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Rindge, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Combined Ergonomic Health Promotion Intervention on Employee Health

NCT02071420
View directory record Official record
Conditions
Sedentary, Overweight
Interventions
Active Workstation Intervention, Ergonomic Intervention, Email Intervention, Bluetooth enabled device (Wahoo Fitness Blue SC sensor) and accompanying iPod application.
Behavioral · Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 22, 2017 · Synced Sep 2, 2026, 10:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted: A Trial of Acute Effects on Biomarkers of Healthy Aging

NCT03511352
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Stand More
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Investigating Sedentary Time in Aging: New Directions

NCT02670369
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Sitting time prompt
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
60 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 2, 2026, 10:51 AM EDT
Withdrawn Not applicable Interventional

The Efficacy of Physical Activity on Improving Health Outcomes for Renal Transplant Patients

NCT04054323
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Physical Activity Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting

NCT02743286
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Walking breaks, Stand more
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

NCT06471374
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome, Delayed Sleep Phase
Interventions
Circadian rhythm assessment, Light sensitivity assessment
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
16 Years to 40 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boulder, Colorado • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health

NCT05353322
View directory record Official record
Conditions
Sedentary Behavior, Cardiometabolic Risk Factors, Blood Pressure, Glucose
Interventions
Sedentary Break (Walking) Condition, Sitting (Control) Condition, Controlled Diet
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Results available

I-STAND R21: Reducing Sedentary Time in Older Adults

NCT02692560
View directory record Official record
Conditions
Obesity, Sedentary Lifestyle
Interventions
I-STAND, Healthy Living
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
60 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571
View directory record Official record
Conditions
Sedentary Behavior, Sedentary Time
Interventions
One 5-Minute Walking Bout Each Hour, One 15-Minute Standing Bout Each Hour, One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour, Uninterrupted Sitting
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)

NCT02970123
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Sit Less, Interact, Move More (SLIMM)
Behavioral
Lead sponsor
Srinvasan Beddhu
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial to Reduce Sitting Time in Postmenopausal Latina Women at Increased Risk for Heart Disease

NCT02905929
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
ActivPAL inclinometer, Phone counseling call: Breaking up sitting time, In-person counseling: Breaking up sitting time, Phone counseling call: Healthy living, Tools to prompt standing, In-person counseling: Healthy living
Device · Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Chula Vista, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 2, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Active Class Space Metabolic Benefits Study

NCT02831309
View directory record Official record
Conditions
Childhood Obesity
Interventions
Light-Intensity Condition, Moderate-Intensity Condition, High-Intensity Condition, Sedentary Condition
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
7 Years to 11 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 2, 2026, 10:51 AM EDT
Not listed Not applicable Interventional

Priming With tDCS: Expanding the Window of Recovery in Chronic Stroke

NCT03964467
View directory record Official record
Conditions
Upper Extremity Paresis
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of the Sciences in Philadelphia
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 2, 2026, 10:51 AM EDT
Recruiting Not applicable Interventional

DevRobust Treatment for Mal de Débarquement Syndrome

NCT05460520
View directory record Official record
Conditions
Mal de Débarquement Syndrome
Interventions
VOR Readaptation, VOR Habituation, Visual Motion Desensitization, Opposing visual motion stimulus
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 78 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 2, 2026, 10:51 AM EDT
Suspended Not applicable Interventional

Intermittent vs Continuous Walking in People With Multiple Sclerosis

NCT03963492
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Walking
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 2, 2026, 10:51 AM EDT