Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 8, 2026, 5:54 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Skin Substitute Clear all

Conditions: Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis
Interventions: Subchondroplasty with Arthroscopy, Arthroscopy Alone; Procedure
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 12
States / cities: Encinitas, California • Loma Linda, California • Stanford, California + 9 more

Conditions: Burns
Interventions: Integra, AlloDerm, Homograft, Autograft; Procedure
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: Up to 90 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2011
U.S. locations: 2
States / cities: Galveston, Texas

Conditions: Diabetic Foot Ulcers
Interventions: DermaPure™, Standard care; Other
Lead sponsor: TRx Wound Care Limited; Industry
Eligibility: 19 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 7
States / cities: Phoenix, Arizona • Miami, Florida • New York, New York + 3 more

Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Spincare matrix; Device
Lead sponsor: Stanford University; Other
Eligibility: 6 Years to 65 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Diabetic Foot Ulcer
Interventions: SOC and Advanced Bioengineered Skin Substitute, SOC and Active Comparator; Device · Other
Lead sponsor: Encoll Corp; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 3
States / cities: Los Angeles, California • South Miami, Florida • Salem, Virginia

Conditions: Diabetic Foot Ulcer
Interventions: DermACELL, GraftJacket, Conventional Care Dressings; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 12
States / cities: Montgomery, Alabama • Tucson, Arizona • Carlsbad, California + 8 more

Conditions: Syndactyly
Interventions: Hyalomatrix, Skin graft; Device · Other
Lead sponsor: Gillette Children's Specialty Healthcare; Other
Eligibility: Up to 17 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Melanoma (Skin), Skin Cancer
Interventions: Intervention; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 120 Years
Enrollment: 307 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Diabetic Foot Ulcer, Lower Extremity Wound
Interventions: DermACELL AWM; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Fresno, California • Rocky Mount, North Carolina

Conditions: Healing of Donor Site, Pain Level
Interventions: AWBAT-D; Device
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Diabetic Foot Ulcer
Interventions: Not listed
Lead sponsor: Solsys Medical LLC; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Washington, Pennsylvania • Newport News, Virginia

Conditions: Surgical Wound, Burns, Trauma Injury
Interventions: SupraSDRM®, NovoSorb® BTM; Device
Lead sponsor: The Metis Foundation; Other
Eligibility: 18 Years to 85 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Skin Substitutes, Secondary Intention Healing, Skin Cancer Healing
Interventions: Skin Substitute, Secondary Intention Healing; Biological
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer
Interventions: TTAX01, Standard care; Biological · Other
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 16
States / cities: Guntersville, Alabama • Tucson, Arizona • Los Angeles, California + 12 more

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: Synthetic Hybrid-Scale Fiber Matrix, Standard of Care, Living Cellular Skin Substitute; Device
Lead sponsor: Acera Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 6
States / cities: Vista, California • Jacksonville, Florida • Miami Beach, Florida + 3 more

Conditions: Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer
Interventions: TTAX01, Standard Care; Biological · Other
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 16
States / cities: San Francisco, California • Sylmar, California • Miami, Florida + 13 more

Conditions: Growth Hormone Deficiency
Interventions: VRS-317; Drug
Lead sponsor: Versartis Inc.; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Venous Leg Ulcers
Interventions: Not listed
Lead sponsor: Solsys Medical LLC; Industry
Eligibility: 21 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2026
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Diabetic Foot Ulcer (DFU), Ulcer Foot, Diabetic Foot, Foot Ulcer
Interventions: Standard of Care, Revita, Relese, Cogenex, Enverse; Other
Lead sponsor: StimLabs; Industry
Eligibility: 18 Years and older
Enrollment: 272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 5
States / cities: Omaha, Nebraska • Tulsa, Oklahoma • Jefferson Hills, Pennsylvania + 2 more

Conditions: Wounds
Interventions: blood draw; Procedure
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 16 Years to 65 Years · Female only
Enrollment: 1,164 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2014
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Diabetic Foot Ulcer
Interventions: Tissue Engineered Skin Substitute, Offloading, Amnionic Membrane Graft; Procedure · Device
Lead sponsor: Professional Education and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 3
States / cities: Martinsville, Virginia • Roanoke, Virginia

Conditions: Nicotine Dependence
Interventions: Nicotine patch, ENDS, Placebo patch, Placebo ENDS; Drug · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Thermal Injury, Deep Partial-Thickness Burn, Full-Thickness Burn
Interventions: Autologous Engineered Skin Substitute, Split-Thickness Autograft (AG); Drug
Lead sponsor: Amarantus BioScience Holdings, Inc.; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Pheonix, Arizona • Houston, Texas • Seattle, Washington

Conditions: Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions: Usual care; Other
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2030
U.S. locations: 1
States / cities: The Woodlands, Texas

Search by objective public record fields.

Subchondroplasty® Knee RCT

Comparison of Skin Substitutes Used in Burn Care

A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers

A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients

Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers

DermACELL in Subjects With Chronic Wounds of the Lower Extremities

Comparison of Scar Formation in Syndactyly Release Surgery With Full Thickness Skin Graft Versus Skin Graft Substitute

Investigation of a Behavioral Substitute for Sunbathing

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

Study Evaluating AWBAT-D Versus the Standard of Care of Split-thickness Skin Graft Donor Sites

Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft

A Prospective Study Using SupraSDRM® in Promoting Healing and Reducing the Time to Grafting of Full-thickness Wounds

Skin Subs vs Secondary Intention

Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU II)

Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)

Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU)

VRS-317 in Adult Subjects With Growth Hormone Deficiency

Comparison of Human Allograft to Apligraf for Venous Leg Ulcers

Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs

Study of Donated Amnion, Fetal Placental Membrane, as Skin Substitute for Burn Patients

Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers

Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment

Safety and Efficacy Study of Autologous Engineered Skin Substitute to Treat Partial- and Full-Thickness Burn Wounds

A Real-World Registry of Chronic Wounds and Ulcers