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Showing 1–24 of 611 matching trials from the live ClinicalTrials.gov search.
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Recruiting Not applicable Interventional Accepts healthy volunteers

Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation

NCT05956951
View directory record Official record
Conditions
Schizophrenia
Interventions
Closed-loop auditory stimulation, Sham auditory stimulation
Device
Lead sponsor
Fabio Ferrarelli
Other
Eligibility
18 Years to 40 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Countermeasures to Circadian Misalignment

NCT04966351
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
Interventions
Time-restricted feeding, Circadian Misalignment
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sleep and Breathing in the General Population - Chemical Stimuli

NCT04720547
View directory record Official record
Conditions
Sleep-disordered Breathing
Interventions
Zolpidem, No Treatment
Drug · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 9, 2026, 9:23 PM EDT
Active, not recruiting Not applicable Interventional

Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear

NCT06009458
View directory record Official record
Conditions
Myopia
Interventions
Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
7 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Mission Viejo, California • Oakland, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional

Nocturnal Hypertension and Non-Dipping Blood Pressure

NCT03128177
View directory record Official record
Conditions
Hypertension, Obstructive Sleep Apnea
Interventions
Dietary sodium
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
48 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional

Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

NCT03300063
View directory record Official record
Conditions
Stroke, Acute
Interventions
Low flow nocturnal oxygen
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Peanut Butter on Sleep Quality and Daily Energy Levels in Fire Fighters

NCT06364202
View directory record Official record
Conditions
Sleep, Body Composition, Blood Pressure, Physical Activity
Interventions
Peanut Butter
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Not applicable Interventional

Differences in Rest, Emotion, and Arousal Modulation in Youth

NCT07476937
View directory record Official record
Conditions
Autism, Sleep Disturbances in Children, Sleep
Interventions
Power Down bedtime manipulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Phase 2 Interventional

Investigation of Sleep in the Intensive Care Unit

NCT03355053
View directory record Official record
Conditions
Delirium, Sleep
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
522 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction

NCT04868539
View directory record Official record
Conditions
Glucose Intolerance, Sleep Deprivation, Sleep
Interventions
Sleep Restriction with ALAN first, then Sleep Restriction without ALAN, Sleep Restriction without ALAN first, then sleep restriction with ALAN
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Phase 2 Interventional

Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis

NCT06428006
View directory record Official record
Conditions
Multiple Sclerosis, Insomnia
Interventions
Cognitive behavioral therapy for insomnia, Sleep and lifestyle education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Insomnia Treatment and Problems (the iTAP Study)

NCT03627832
View directory record Official record
Conditions
Insomnia, Alcohol; Harmful Use
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep Hygiene
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 30 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Results available

Scheduled Awakenings for the Treatment of Nocturnal Enuresis

NCT03047720
View directory record Official record
Conditions
Nocturnal Enuresis
Interventions
Lully Sleep Guardian
Device
Lead sponsor
Indiana University
Other
Eligibility
5 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Restriction in Women

NCT02835261
View directory record Official record
Conditions
Sleep, Cardiovascular Disease, Obesity
Interventions
Sleep Restriction
Other
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 75 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Deprivation and Energy Balance

NCT00935402
View directory record Official record
Conditions
Obesity
Interventions
Sleep
Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
30 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2011 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Results available

Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery

NCT01505465
View directory record Official record
Conditions
Postoperative Pain, Delirium, Confusion, Sleep
Interventions
Melatonin, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Not applicable Interventional

A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers

NCT06809335
View directory record Official record
Conditions
Shift Work Sleep Disorder
Interventions
Personalized circadian mHealth
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Research Framework Exploring Sleep Health

NCT05197738
View directory record Official record
Conditions
Sleep, Sleep Apnea, Obesity, Mood
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2041
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional

Remote Study of NightWare for PTSD With Nightmares

NCT03934658
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders, Combat Disorders, Nightmares Associated With Chronic Post-Traumatic Stress Disorder, Nightmare, Nightmares, REM-Sleep Type
Interventions
NightWare Therapeutic System, NightWare Therapeutic System in Sham Mode
Device
Lead sponsor
NightWare
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Sep 9, 2026, 9:23 PM EDT
Recruiting Phase 1Phase 2 Interventional

Atomoxetine and DAW2022 on OSA Severity

NCT05350215
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral capsule, Atomoxetine Oral Capsule [Strattera]
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Hypnotic Medications and Memory: Effect of Drug Exposure During the Night

NCT01159652
View directory record Official record
Conditions
Sleep, Memory
Interventions
zaleplon, zolpidem extended release, bedtime placebo, middle of the night placebo
Drug
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
18 Years to 50 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 25, 2014 · Synced Sep 9, 2026, 9:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Repeated Challenge of Insufficient Sleep: Endothelial Effects

NCT01523535
View directory record Official record
Conditions
Repeated Short Sleep Schedule
Interventions
repeated cycles of short sleep
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
25 Years to 55 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Sep 9, 2026, 9:23 PM EDT