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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:58 AM EDT

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Showing 145–168 of 260 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sleep Restriction Clear all
Not listed Not applicable Interventional

Sleep Treatment for Addiction Recovery

NCT04198311
View directory record Official record
Conditions
Insomnia, Alcohol Use Disorder, Substance Use Disorders
Interventions
CBT-I
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2011 · Synced Oct 20, 2026, 6:58 AM EDT
Recruiting Not applicable Interventional

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

NCT05663034
View directory record Official record
Conditions
Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress, Sleep, Memory Impairment, Cognitive Behavioral Therapy, Concussion, Brain, Head Injury, Brain Injury Traumatic Mild
Interventions
Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Eglin Air Force Base, Florida • Bethesda, Maryland • Fort Bragg, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individual Differences in Diabetes Risk: Role of Sleep Disturbances

NCT00989976
View directory record Official record
Conditions
Sleep, Diabetes
Interventions
normal sleep times, bedtime restriction
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 29 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional

Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

NCT00004569
View directory record Official record
Conditions
Sleep-Disordered Breathing
Interventions
Non-invasive technique to diagnose and quantitate sleep-disordered breathing
Procedure
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)

NCT00393874
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders, Insomnia, Nightmares
Interventions
Behavioral Sleep Intervention, Prazosin, Placebo
Behavioral · Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Phase 4 Interventional Results available

CBT-I or Zolpidem/Trazodone for Insomnia

NCT04468776
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Zolpidem, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), Trazodone
Drug · Behavioral
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Birmingham, Alabama • Tucson, Arizona • Columbia, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Energy Expenditure

NCT01751581
View directory record Official record
Conditions
Obesity
Interventions
Short Sleep, Habitual sleep
Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2013 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction

NCT02256865
View directory record Official record
Conditions
Insulin Resistance
Interventions
Ketoconazole, Hydrocortisone, Testosterone, Placebo for ketoconazole, Placebo for hydrocortisone, Placebo for testosterone
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
22 Years to 45 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional

Sleep To Reduce Incident Depression Effectively

NCT03322774
View directory record Official record
Conditions
Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions
digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Sleep Health Enhancement in Older Adults to Address Frailty

NCT05968820
View directory record Official record
Conditions
Frailty
Interventions
Sleep Health Enhancement Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of a Sleep Debt in Middle-Aged and Older Adults

NCT00817700
View directory record Official record
Conditions
Sleep Restriction
Interventions
Sleep restriction
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 20, 2026, 6:58 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction - Axis Study

NCT03142893
View directory record Official record
Conditions
Sleep Restriction
Interventions
Ketoconazole Pill, Ganirelix, Dexamethasone, Dexamethasone Injection, Cosyntropin Injectable Product, Recombinant Human Luteinizing Hormone, Hydrocortisone Injection, Gonadorelin, Corticorelin, Placebo oral capsule, Saline Solution, Saline Solution for Injection
Drug
Lead sponsor
Peter y. Liu
Other
Eligibility
22 Years to 45 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Terminated Not applicable Interventional Results available

CBT-I for Cannabis Use

NCT02102230
View directory record Official record
Conditions
Marijuana Abuse, Sleep Initiation and Maintenance Disorders
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Insomnia Plus Mobile App (CBT-I-MA), Desensitization Treatment for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 20, 2026, 6:58 AM EDT
Recruiting Phase 2 Interventional

Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection

NCT06434571
View directory record Official record
Conditions
Multiple Sclerosis, Insomnia
Interventions
Telehealth cognitive behavioral therapy for insomnia (tCBT-I), Web-based cognitive behavioral therapy for insomnia (wCBT-I), Treatment as usual (TAU)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 6:58 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women

NCT04037605
View directory record Official record
Conditions
Sleep Restriction
Interventions
Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill, Dexamethasone injection, Cosyntropin Injectable Product, Recombinant Human Luteinizing Hormone (also known as luveris), Hydrocortisone Injection (also known as solu-cortef), Gonadorelin (also known as Lutrepulse), Corticorelin (also known as Acthrel), Placebo oral tablet, Saline Solution, Saline solution for injection
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
60 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Summertime: Kids in Motion

NCT03947918
View directory record Official record
Conditions
Sleep
Interventions
Short sleep, Long sleep
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
8 Years to 10 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

NCT03012425
View directory record Official record
Conditions
Insomnia, Related Distress Among Cancer Caregivers
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires, Diurnal Cortisol
Behavioral · Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
3
States / cities
Irvine, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Extended Work Schedules, Sleep Loss and Health

NCT00989534
View directory record Official record
Conditions
Sleep
Interventions
Fixed restricted bedtimes, Sleep restriction with circadian misalignment
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 39 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Oct 20, 2026, 6:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep

NCT02945501
View directory record Official record
Conditions
Sleep Deprivation, Mental Competency
Interventions
NeuroConn DC Stimulator PLUS, SHAM TES
Device
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks

NCT03375099
View directory record Official record
Conditions
Intentional Self-Harm by Other Specified Means
Interventions
Lethal Means Counseling, Health and Stress Reduction
Behavioral
Lead sponsor
University of Southern Mississippi
Other
Eligibility
18 Years to 60 Years
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional

Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial

NCT04936321
View directory record Official record
Conditions
Insomnia, Migraine Disorders, Headache Disorders
Interventions
Internet-delivered CBT for Insomnia, Internet-delivered CBT for Pain Management, Internet-delivered Sleep Education
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 20, 2026, 6:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sleep Restriction on BAT Activation in Humans

NCT02770118
View directory record Official record
Conditions
Sleep Deprivation, Obesity
Interventions
Partial Sleep Restriction, Total Sleep Deprivation, Habitual Sleep
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 49 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 20, 2026, 6:58 AM EDT