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Showing 1–24 of 257 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sleep restriction Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Active, not recruiting Not applicable Interventional

Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing

NCT06036420
View directory record Official record
Conditions
ADHD
Interventions
Flashed Light Therapy, Videoconference-delivered Cognitive Behavioral Therapy
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dyadic Sleep Study

NCT06569693
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
My Sleep Our Sleep (MSOS) Program, Brief Behavioral Treatment for Insomnia (BBTI)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Coral Gables, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional

Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial

NCT04936321
View directory record Official record
Conditions
Insomnia, Migraine Disorders, Headache Disorders
Interventions
Internet-delivered CBT for Insomnia, Internet-delivered CBT for Pain Management, Internet-delivered Sleep Education
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 4 Interventional

Solriamfetol and CBT-I in Patients With Insomnia Disorder

NCT05838430
View directory record Official record
Conditions
Insomnia
Interventions
Solriamfetol 75 MG, Cognitive Behavioral Therapy for Insomnia (CBT-I), Monitoring, Placebo
Drug · Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
25 Years to 60 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

NCT04632628
View directory record Official record
Conditions
Insomnia Chronic, Dementia
Interventions
Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Circadian Time Restricted Eating

NCT05628012
View directory record Official record
Conditions
Circadian Rhythm, Cardiometabolic Health, Weight Loss, Cardiovascular Health, Time Restricted Feeding
Interventions
Circadian Based Time Restricted Eating
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sleep Duration and Architecture on Insulin Sensitivity

NCT01396941
View directory record Official record
Conditions
Insulin Resistance
Interventions
Sleep restriction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2021 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional

Improving Sleep in Gynecologic Cancer Survivors

NCT05044975
View directory record Official record
Conditions
Sleep Disturbance, Gynecologic Cancer
Interventions
Sleep restriction, Stimulus control, Systematic light exposure
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Tucson, Arizona • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Early Phase 1 Interventional

Time Restricted Eating in Sleep Apnea

NCT06047496
View directory record Official record
Conditions
Time Restricted Eating, Obstructive Sleep Apnea
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nighttime Synchrony of Your Nutrition and Circadian Health

NCT07329283
View directory record Official record
Conditions
Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors, Sleep Hygiene, Sleep Hygiene, Inadequate, Sleep Deprivation, Insufficient Sleep, Circadian Misalignment, Circadian Dysregulation, Light Exposure
Interventions
Central Clock Misalignment, Peripheral Misalignment
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Behavioral Treatment of Menopausal Insomnia; Sleep and Daytime Outcomes

NCT01933295
View directory record Official record
Conditions
Menopause
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Education, Sleep Restriction Therapy
Behavioral
Lead sponsor
Christopher Drake
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation

NCT04269239
View directory record Official record
Conditions
Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Healthy Habits, Sleep Habits
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
40 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Galveston, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Targeted Melanoma Detection With Skin Self-Examination During COVID-19 Restricted Physician Access

NCT04420273
View directory record Official record
Conditions
Melanoma
Interventions
SSE educational intervention, Active control:Healthy Living
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 3, 2026, 1:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sleep and Food-based Decision Making

NCT05728983
View directory record Official record
Conditions
Sleep
Interventions
Sleep levels
Other
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 40 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Research on Expecting Moms and Sleep Therapy

NCT02805998
View directory record Official record
Conditions
Insomnia
Interventions
Web-based CBT-I, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional

Sleep Bootcamp: A Pilot Tele-Sleep Program for Former National Football League (NFL) Players

NCT04159233
View directory record Official record
Conditions
Sleep, Insomnia, Pain, Quality of Life
Interventions
Brief Behavioral Therapy for Insomnia (BBTI)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of a Sleep Debt in Middle-Aged and Older Adults

NCT00817700
View directory record Official record
Conditions
Sleep Restriction
Interventions
Sleep restriction
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

NCT00895570
View directory record Official record
Conditions
Sleep Restriction, Impaired Glucose Metabolism
Interventions
modafinil, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2009 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

eHealth Insomnia Intervention for Adult Survivors of Childhood Cancer

NCT04317742
View directory record Official record
Conditions
Childhood Cancer, Insomnia, Neurocognitive Impairment, Survivorship, Late Effect, Sleep
Interventions
Sleep Healthy Using the Internet (SHUTi) Intervention Group, Online Patient Education (PE) Control Group
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
1,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Intervention in Depression

NCT06080932
View directory record Official record
Conditions
Depression, Ketosis
Interventions
Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Digital Cognitive-Behavioral Therapy for Insomnia in Spanish Speaking Latinas/os (Dormir Mejor Study)

NCT05353296
View directory record Official record
Conditions
Insomnia
Interventions
Digital cognitive behavioral therapy for insomnia (CBT-I) program, Minimally Enhanced Usual Care (mEUC), Somryst (culturally adapted)
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Active, not recruiting Not applicable Interventional

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

NCT05356364
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal Understanding of Mindful Awareness for Sleep (PUMAS)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 3, 2026, 1:09 AM EDT