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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:34 PM EDT

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Showing 1–24 of 145 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Smoking Cessation Behavioral Program Clear all
Completed Phase 4 Interventional Results available

Engagement With an Adaptive Mobile Health Smoking Cessation Intervention

NCT04020718
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Brief telephone advice plus tailored text messages, Mailed nicotine replacement therapy, Proactive telephone coaching
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Physical Activity as Part of a Smoking Cessation Program

NCT00403312
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smoking Cessation Behavioral Program, Nicotine Patch, Physical Activity
Behavioral · Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 2, 2008 · Synced Oct 22, 2026, 2:34 PM EDT
Active, not recruiting Not applicable Interventional

Developing an E-Cigarette Cessation Intervention for Hispanic/Latina(o) Youth in Florida: The BReATHE Study

NCT07192601
View directory record Official record
Conditions
Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
Interventions
E-cigarette Cessation Manual
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Increasing Digital Equity and Access Among Rural Patients (IDEA) Study

NCT05209451
View directory record Official record
Conditions
Smoking Cessation
Interventions
Digital, evidence-based behavioral health program for smoking cessation, Bluetooth enabled iPad, Coaching Support
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Clinical Trial of an Automated Smartphone Based Smoking Cessation Treatment

NCT02930200
View directory record Official record
Conditions
Smoking Cessation
Interventions
Treatment as Usual, QuitGuide, Smart-T
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone Application for Smoking Cessation

NCT02134509
View directory record Official record
Conditions
Smoking
Interventions
Experimental App, Active Comparator App
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
511 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

End Nicotine Dependence Clinic

NCT03290430
View directory record Official record
Conditions
Smoking Cessation
Interventions
Group Counseling, Individual Counseling, Phone Counseling, Video Counseling, Texting support, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 22, 2026, 2:34 PM EDT
Recruiting Not applicable Interventional

Behavioral Intervention for Youth to Promote Vaping Cessation

NCT06765291
View directory record Official record
Conditions
Vaping, Vaping Teens, Nicotine Dependence
Interventions
QuitVaping, This is Quitting (TIQ)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 19 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Phase 4 Interventional Results available

Tobacco Use Treatment in Cancer Patients

NCT03482583
View directory record Official record
Conditions
Smoking, Cigarette
Interventions
Nicotine Replacement Therapy, Referral to AHEC/Quitline
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Behavioral Treatment for Substance Abuse

NCT01438346
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Substance Abuse Education, Mind-body Bridging
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 2, 2016 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke

NCT00307203
View directory record Official record
Conditions
Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
Interventions
bupropion SR, Cognitive Behavioral Group Therapy, nicotine replacement therapy
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 22, 2026, 2:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

NCT05641974
View directory record Official record
Conditions
Smoking, Cigarette Smoking
Interventions
Helpers Stay Quit Training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
940 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

'Questions About Quitting' Smoking Cessation Trial

NCT00992264
View directory record Official record
Conditions
Smoking
Interventions
Message Tone, Navigation, Proactive Outreach, Testimonials
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,865 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV

NCT04505371
View directory record Official record
Conditions
HIV Infections, Smoking, Smoking Cessation
Interventions
Wellness Intervention for Smokers with HIV
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathe Easier II: A Dyad-based Multiple Behavior Intervention

NCT05956782
View directory record Official record
Conditions
Lung Cancer, Nonsmall Cell, COPD, Self-Management, Physical Inactivity, Stress, Quality of Life
Interventions
Breathe Easier
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Denver Health Cardiovascular Disease (CVD) Prevention Program

NCT00829491
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
CVD risk reduction program
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
30 Years to 64 Years
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 17, 2012 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Women Engaging in Quitting Smoking Together

NCT02453659
View directory record Official record
Conditions
Smoking Cessation
Interventions
Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE), Smoking Cessation counseling, Transdermal Nicotine Patch
Behavioral · Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 28, 2019 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Kids Safe and Smokefree (KiSS)

NCT01745393
View directory record Official record
Conditions
Second Hand Tobacco Smoke, Nicotine Dependence
Interventions
Clinic Quality Improvement + Behavioral Counseling, Clinic Quality Improvement + Attention Control
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Phase 4 Interventional Results available

Varenicline for Nicotine Vaping Cessation in Adolescents

NCT05367492
View directory record Official record
Conditions
Vaping, Nicotine Dependence
Interventions
Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years to 25 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Smoking Termination Enhancement Project (STEP)

NCT01065506
View directory record Official record
Conditions
Smoking
Interventions
Cognitive Behavioral Treatment, Nicotine Patch, Wellness Program, Aerobic Exercise
Behavioral · Drug
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 22, 2026, 2:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Conservative and Aggressive Smoking Cessation Treatment Strategies in a Vascular Surgery Office Practice

NCT01850589
View directory record Official record
Conditions
Smoking Cessation
Interventions
Aggressive Therapy
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Smoking Treatment and Anxiety Management Program

NCT01753141
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Cognitive Behavioral Therapy for smoking cessation, Cognitive Behavioral Therapy for smoking cessation and anxiety sensitivity reduction.
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
378 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 26, 2013 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
View directory record Official record
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 22, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Homes, Healthy Habits

NCT03433456
View directory record Official record
Conditions
Obesity, Obesity, Childhood, Obesity; Familial
Interventions
Home visitation + HABITS program, Standard home visitation program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
0 Years to 75 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Oct 22, 2026, 2:34 PM EDT