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ClinicalTrials.gov public records Last synced Nov 13, 2026, 10:20 PM EST

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Showing 1–24 of 89 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Smoking Relapse Prevention Clear all

Conditions: Smoking Cessation
Interventions: SMS USA; Behavioral
Lead sponsor: Center for Innovative Public Health Research; Other
Eligibility: 18 Years to 25 Years
Enrollment: 164 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Santa Ana, California

Conditions: Nicotine Dependence
Interventions: Placebo, Varenicline; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking, Smoking Cessation
Interventions: Nicotine Patch, Tobacco Quit Line Program; Drug · Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 1,298 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 2
States / cities: Memphis, Tennessee • Lackland Air Force Base, Texas

Conditions: Smoking, Smoking Cessation, HIV
Interventions: Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling, "Crave-to-Quit" app, vDOT "emocha" app; Drug · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe, Smoking, Hookah, Nicotine Dependence
Interventions: BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 2,999 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Lackland Air Force Base, Texas

Conditions: Nicotine Addiction
Interventions: Standard smoking cessation counseling; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking
Interventions: Smoking Relapse Prevention; Behavioral
Lead sponsor: Loma Linda University; Other
Eligibility: Up to 1 Week
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Schizophrenia, Schizoaffective Disorder, Smokers
Interventions: bupropion + nicotine patch + nicotine gum or lozenges, Placebo pill + placebo patch; Drug
Lead sponsor: North Suffolk Mental Health Association; Other
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Cessation
Interventions: Standard Care, smoking cessation DVD, PTF DVD; Behavioral
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 1,050 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch, Nicotine Lozenge, Survey Administration, Interview; Device · Drug · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 854 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tobacco-Related Carcinoma
Interventions: Behavioral Intervention, Informational Intervention, Nicotine Replacement, Telephone-Based Intervention; Behavioral · Other · Drug
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking
Interventions: Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion, Transdermal nicotine patch, Nicotine polacrilex, Nicotine lozenge; Behavioral · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking, Tobacco Smoking, Nicotine Dependence, Smoking Cessation
Interventions: Mindfulness Training, Smoking Cessation Therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Smoking Cessation, Pregnancy
Interventions: Phone-based postpartum continuing care, Standard care; Behavioral
Lead sponsor: Battelle Memorial Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Bloomington, Illinois • Baltimore, Maryland

Conditions: Smoking ( Cigarette), Breastfeeding
Interventions: Breastfeeding promotion, Attention placebo control; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older · Female only
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking, Smoking Cessation
Interventions: Comprehensive Relapse Prevention Intervention, Standard Treatment Counseling, Nicotine Replacement Therapy (NRT); Behavioral · Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 100 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic
Interventions: BTSCS, StSST; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland

Conditions: Smoking Cessation
Interventions: Reduction Phone Counseling, Abrupt Phone Counseling, Minimal Abrupt Phone Counseling, Pre-Quit Nicotine Lozenges, Post-Quit Nicotine Lozenges; Behavioral · Drug
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 750 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Smoking Cessation
Interventions: rTMS Active 20Hz, rTMS Sham; Device
Lead sponsor: The City College of New York; Other
Eligibility: 21 Years to 65 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Nicotine Dependence, Major Depressive Disorder
Interventions: Varenicline, BASC, Standard treatment; Drug · Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 2
States / cities: Chicago, Illinois • Philadelphia, Pennsylvania

Conditions: Smoking Cessation
Interventions: Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 50 Years to 80 Years
Enrollment: 1,188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Alcoholism, Smoking
Interventions: bupropion (Wellbutrin), Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 195 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2007
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Smoking Cessation
Interventions: BTSCS; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 75 Years
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 3
States / cities: Baltimore, Maryland • Timonium, Maryland

Conditions: Tobacco Use Disorder
Interventions: Bupropion; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 75 Years
Enrollment: 589 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2006
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Smoking Cessation Via Text Messaging: Feasibility Testing of Stop My Smoking USA

Effects of Chantix on Relapse Prevention for Smoking Cessation

Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)

Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients

Evaluation of a Brief Tobacco Intervention in the US Military

Neural Mechanisms Associated With Risk of Smoking Relapse

Prevention of Postpartum Smoking Relapse in Mothers of Infants in the Neonatal Intensive Care Unit (NICU)

Smoking Relapse Prevention in Schizophrenia

Enhancing Quitline Services for African American Smokers

iCanQuit Smoking Cessation Among Hispanic Adults

Episodic Future Thinking and Future Thinking Priming for Smoking Cessation

Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)

Mindfulness Training for Smoking Cessation

Phone-Based Postpartum Continuing Care for Smoking Cessation

Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion

Preventing Smoking Relapse After Total Joint Replacement Surgery

Smoking Cessation for Veterans With Severe and Persistent Mental Illness

Gradual vs. Abrupt Cessation Treatment for Smoking

Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation

Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers

Tobacco Education and Lung Health Study (TEAL)

Pharmacologic Relapse Prevention for Alcoholic Smokers

An Integrated Approach to Smoking Cessation in Severe Mental Illness (SMI)

Maintenance Treatment for Abstinent Smokers