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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:22 AM EST

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Showing 49–72 of 228 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Smoking abstinence Clear all

Conditions: Smoking Cessation
Interventions: Contingency management, Nicotine replacement therapy, Varenicline, Additional behavioral support; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Reduction or Abstinence
Interventions: In vivo counseling, Standard Smoking Cessation Counseling; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 517 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Cigarette Smoking
Interventions: CO-Contingent, Control condition; Behavioral
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 13 Years to 19 Years
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obesity, Smoking Cessation
Interventions: ENDS, CI, No ENDS, NI; Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 99 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking Cessation
Interventions: F phase lab session, L phase lab session; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking Cessation
Interventions: Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Motivational Intervention, Nicotine Anonymous, Cognitive Behavior Therapy, Relaxation Therapy
Interventions: Motivational Intervention, Relaxation Therapy, Cognitive Behavioral Therapy, Self-Help Programming; Behavioral
Lead sponsor: University of Rhode Island; Other
Eligibility: 13 Years to 19 Years
Enrollment: 314 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Cranston, Rhode Island

Conditions: Smoking
Interventions: THS 2.2 Menthol (mTHS 2.2), Menthol Conventional Cigarette (mCC), Smoking Abstinence (SA); Other
Lead sponsor: Philip Morris Products S.A.; Industry
Eligibility: 22 Years and older
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Daytona Beach, Florida • Dallas, Texas

Conditions: Alcoholism, Smoking
Interventions: bupropion (Wellbutrin), Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 195 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2007
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Substance Withdrawal Syndrome
Interventions: Abstinence from e-cigarettes; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Smoking, Alcoholism
Interventions: Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Newington, Connecticut

Conditions: Smoking, ADHD
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking, Homeless Persons
Interventions: Bupropion, Nicotine replacement therapy, Contingency Management; Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Dependence
Interventions: S-Adenosyl-L-Methionine, placebo; Drug · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 2
States / cities: Rochester, Minnesota • La Crosse, Wisconsin

Conditions: Smoking, Smoking Cessation, Tobacco Use
Interventions: Smoking Abstinence; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 24 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Tobacco Use Disorder
Interventions: Smartphone-based Financial Incentives, Best Practices; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Cigarette Smoking, Tobacco Use
Interventions: Placebo, Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Veteran, Smoking Cessation
Interventions: Abstinence Reinforcement Therapy (ART), Telephone Counseling and NRT; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Cessation, Pregnancy Related
Interventions: SmartWatch SmokeBeat Application; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: Female only
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Tobacco Abuse Cigarette
Interventions: Quitline facilitation intervention, Brief stop-smoking intervention; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Use
Interventions: Ploom HTP Menthol HTS; MX3 (681), Ploom HTP Tobacco HTS; R8 (120), Smoking Abstinence (menthol), Smoking Abstinence (non-menthol); Other
Lead sponsor: Altria Client Services LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 921 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 8
States / cities: Bentonville, Arkansas • Rogers, Arkansas • Overland Park, Kansas + 5 more

Conditions: Cigarette Smoking
Interventions: NIDA Standard Research E-cigarette (SREC); Device
Lead sponsor: University of Southern California; Other
Eligibility: 22 Years to 55 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cigarette Smoking, Tobacco Smoking
Interventions: Motivational Interviewing/CBT, CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL); Behavioral · Other
Lead sponsor: Memorial Hospital of Rhode Island; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Pawtucket, Rhode Island

Conditions: Smoking Cessation
Interventions: Financial Incentives (FI) and Nicotine Replacement Therapy (NRT); Behavioral
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Burlington, Vermont

Search by objective public record fields.

A Smoking Cessation Intervention for Yale Dining Employees

In Vivo Experience With NRT to Increase Adherence and Smoking Abstinence

Contingency Management for Smoking Abstinence With Adolescent Smokers

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

Smoking, Stress & Allopregnanolone Response

Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers

Motivation and Skills for Detained Teen Smokers

Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting

Pharmacologic Relapse Prevention for Alcoholic Smokers

Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?

Combination Nicotine Replacement for Alcoholic Smokers

Neuroimaging of Smokers With and Without Attention Deficit Hyperactivity Disorder (ADHD)

Contingency Management for Smoking Cessation in Homeless Smokers

S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence

BRP1802 Smoking Abstinence Study

Smartphone-based Financial Incentives

Gabapentin for Smoking Cessation

Abstinence Reinforcement Therapy (ART) for Rural Veteran Smokers

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

Helping Hospitalized Patients Quit Smoking

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Are Smokers Switching to Vaping at Lower Risk for Cancer? (Electronic Cigarettes and Cancer Risk)

Working Inside for Smoking Elimination

Remote Smoking Cessation in Hospitalized Cardiac Patients