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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:17 AM EST

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Showing 145–168 of 228 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Smoking abstinence Clear all

Conditions: Tobacco Use Cessation
Interventions: Standard contest (1 month), Motivational and Problem-Solving, Extended Contests; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 1,318 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Smoking
Interventions: Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 21 Years to 50 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking
Interventions: Quit smoking, Nicotine patch, Placebo Patch; Behavioral · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking Cessation
Interventions: Spanish-Language Version of the Stop Smoking for Good, NCI-Produced Spanish-language Self-help Booklet; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1,417 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cigarette Smoking, Hypertension
Interventions: Varenicline, behavioral therapy; Drug · Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 203 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Smoking
Interventions: Varenicline, placebo, bupropion SR; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 506 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Rochester, Minnesota • La Crosse, Wisconsin

Conditions: Tobacco Use Disorder, Tobacco Dependence, Smoking
Interventions: Anatabloc(TM), CigRx(R); Dietary Supplement
Lead sponsor: Rock Creek Pharmaceuticals, Inc.; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 109 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Cigarette Smoking, Nicotine Dependence, Nicotine Withdrawal
Interventions: Smoking Abstinence, Ad Lib Smoking; Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 21 Years to 55 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Smoking Cessation, Acceptability of Health Care, Nicotine Dependence, Cigarettes
Interventions: Abstinent Contingent (AC) Re-Connect; Behavioral
Lead sponsor: Rowan University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Glassboro, New Jersey

Conditions: Smoking Cessation
Interventions: Mobile Contingency Management; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 64 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Smoking Cessation, Pregnancy
Interventions: Text Messages, Incentives; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Smoking, Cigarette
Interventions: Financial Incentive Treatment (FIT); Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Athens, Georgia • Tulsa, Oklahoma

Conditions: Cigarette Smoking
Interventions: contingency management, Standard of Care; Behavioral · Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Nicotine Vaping, Nicotine, Vaping
Interventions: CA35, CM35, Cig; Other
Lead sponsor: Philip Morris Products S.A.; Industry
Eligibility: 24 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Nicotine Dependence
Interventions: Brief Motivational Intervention, Contingency Management, Non-Contingent Reinforcement; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Tobacco Use Disorder, Schizophrenia
Interventions: smoking abstinence; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking Cessation, Diabetes Mellitus, Type 2
Interventions: Financial incentives; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 75 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: HIV Infections, Sexually Transmitted Diseases
Interventions: Abstinence-only HIV/STD risk-reduction intervention, Safer-sex-only HIV/STD risk-reduction intervention, Long comprehensive HIV/STD risk-reduction intervention, Short comprehensive HIV/STD risk-reduction intervention, Health promotion control intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: Not listed
Enrollment: 662 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sex, Cigarette Smoking
Interventions: Abstinence and Smoking; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 45 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hepatitis C, Smoking Cessation
Interventions: Cognitive Behavioral Counseling; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Smoking Cessation
Interventions: Yoga, Yoga and Cognitive Behavioral Therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cigarette Smoking, Nicotine Withdrawal
Interventions: Smoking Abstinence, Ad Lib Smoking; Other
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking, Cigarette Smoking
Interventions: Helpers Stay Quit Training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 99 Years
Enrollment: 940 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Tobacco Use Disorder
Interventions: Neutral or active cigarette cues; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 45 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: New York, New York

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Quit and Win Contests to Improve Smoking Cessation Among College Students

Heart Rate Variability Biofeedback for Smoking Cessation

Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction

Spanish-Language Smoking Cessation Trial

Smoking Study With Behavioral Therapy for Hypertensive Patients

Varenicline and Bupropion for Smoking Cessation

Study to Evaluate the Safety and Efficacy of Dietary Supplement Anatabloc in Reducing Daily Smokers' Urge to Smoke

Nicotine Withdrawal and Reward Processing

Re-Connect Application for Smoking Cessation

Mobile Contingency Management for Smoking Cessation (R01 Supplement) (PrevailGO)

Preliminary Effectiveness of Enhanced Text Message + Incentives

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Contingency Management and Pharmacotherapy for Smoking Cessation

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

Incentives to Promote Smoking Cessation in Low SES Women

Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls

Incentivized Smoking Cessation for Diabetics

Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents

Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers

HCV-Smoking Cessation Study

Preventing Postpartum Relapse to Smoking Using Yoga and Cognitive Behavioral Therapy: A Randomized Pilot Study

Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-world Behavior

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

Effect of Smoking Exposure on Smoking Relapse Following Brief Abstinence - 2