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ClinicalTrials.gov public records Last synced Oct 4, 2026, 3:30 PM EDT

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Showing 49–72 of 180 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Smoking as Usual Clear all
Completed Phase 4 Interventional Results available

Integrating Financial Management Counseling and Smoking Cessation Counseling to Reduce Health and Economic Disparities in Low-Income Immigrants

NCT03187730
View directory record Official record
Conditions
Smoking Cessation
Interventions
Integrated Smoking Cessation and Financial Counseling, Waitlist Integrated Smoking Cessation and Financial Counseling, Nicotine Replacement Therapy (NRT)
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional

Technology Assisted Motivational Interviewing

NCT06713603
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
TAMI Coach
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

NCT03199651
View directory record Official record
Conditions
Cigarette Smoker, Current Smoker, Lung Adenocarcinoma, Squamous Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer
Interventions
Best Practice, Biospecimen Collection, Laboratory Biomarker Analysis, Medical Chart Review, Quality-of-Life Assessment, Questionnaire Administration, Smoking Cessation Intervention
Other · Procedure · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3,584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Phase 2 Interventional Results available

Effect of Ramelteon on Smoking Abstinence

NCT02560324
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Ramelteon, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 4, 2026, 3:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Smoking Relapse Prevention Via Just-in-Time-Adaptive Interventions

NCT03690596
View directory record Official record
Conditions
Smoking Cessation
Interventions
NRT + QuitBuddy, NRT + QuitBuddy-Recall, Treatment as Usual
Other
Lead sponsor
Meharry Medical College
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional

Vaping and Smoking Project in People With Schizophrenia

NCT06944847
View directory record Official record
Conditions
Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Interventions
Acute (24-hour) abstinence, Ad libitum smoking/vaping
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
21 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)

NCT04200534
View directory record Official record
Conditions
Smoking, Lung Cancer
Interventions
Best Practice, Nicotine Patch, Quality-of-Life Assessment, Questionnaire Administration, Tobacco Cessation Counseling
Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
55 Years to 77 Years
Enrollment
358 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
3
States / cities
Galveston, Texas • Houston, Texas • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Randomized Control Trial of Financial Incentives for Smoking Cessation

NCT01303081
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Individual Rewards, Fixed Deposits, Chosen Deposits, Competitive Deposits (Pari-Mutuel), Usual Care
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2012 · Synced Oct 4, 2026, 3:30 PM EDT
Completed No phase listed Observational

Nicotinic Receptor Levels After Stopping Smoking

NCT01704573
View directory record Official record
Conditions
Nicotine Addiction
Interventions
2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

New Strategies to Enhance Smoking Cessation

NCT06751927
View directory record Official record
Conditions
Smoking Cessation
Interventions
Educational Video
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional

An Evaluation of Clinical Pharmacist-led Intervention on Clinical Outcomes in Patients With Ischemic Stroke

NCT01876667
View directory record Official record
Conditions
Stroke
Interventions
Intervention (CPCRS) Group, Placebo
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 85 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Results available

Adjunctive Mood Management for Telephone-based Smoking Cessation

NCT02500589
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Behavioral mood management, Health education
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation

NCT03912194
View directory record Official record
Conditions
Tobacco Dependence
Interventions
cognitive-behavioral withdrawal regulation strategies, relaxation strategies, early withdrawal exposure
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Studies of Smoking and Treatment

NCT03085602
View directory record Official record
Conditions
Smoking Cessation
Interventions
Cognitive behavioral therapy, Health education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 4, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Smoking Cessation CM for Veterans With or at Risk for Cancer

NCT06432985
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorder
Interventions
Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Results available

Nonsmokers Helping Smokers Quit

NCT02010697
View directory record Official record
Conditions
Smoking Cessation
Interventions
Messages targeting nonsmokers, Messages targeting smokers
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
3,125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine

NCT05994703
View directory record Official record
Conditions
Smoking Cessation, Harm Reduction
Interventions
d-cycloserine, Juul e-cigarette
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Active, not recruiting Not applicable Interventional

A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities

NCT05671380
View directory record Official record
Conditions
Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
Interventions
Longitudinal Proactive Outreach (LPO)., Ask-Advice-Connect (AAC)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional

The Effects of a Self-management Intervention on Low Literacy Patients With Chronic Obstructive Pulmonary Disease (COPD)

NCT01327456
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Self-Management Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2011 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional

Get With the Guidelines in ED Patients With Heart Failure

NCT02519283
View directory record Official record
Conditions
Heart Failure
Interventions
GUIDED-HF, Standard of Care
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
15
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Iowa City, Iowa + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Extended Self-Help for Smoking Cessation

NCT01352195
View directory record Official record
Conditions
Smoking Cessation
Interventions
Forever Free Booklets
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
2,124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Phase 4 Interventional

Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient

NCT01277250
View directory record Official record
Conditions
Cigarette Smoking, Home Access to Internet and Email, Cognitively and Physically Able to Participate, English Speaking and Reading
Interventions
Web-based smoking cessation program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
1,548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 19, 2015 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Smoking Cessation & Anxiety in People With HIV

NCT01393301
View directory record Official record
Conditions
Nicotine Dependence, Symptoms of Anxiety, HIV
Interventions
Integrated cognitive-behavioral therapy for smoking cessation and anxiety, Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 4, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Relapse-Prevention Booklets as an Adjunct to a Tobacco Telephone Helpline("Quitline")

NCT01352000
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smoking Cessation
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,830 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 4, 2026, 3:30 PM EDT