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ClinicalTrials.gov public records Last synced Sep 30, 2026, 2:18 AM EDT

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Showing 1–24 of 345 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Smoking cessation plus Health and Wellness Clear all
Not yet recruiting Not applicable Interventional

Smartphone-based Incentives Intervention to Increase Smoking Cessation During Pregnancy

NCT07840118
View directory record Official record
Conditions
Smoking During Pregnancy and Postpartum, Perinatal Cigarette Smoking
Interventions
Best Practices, Financial Incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Phase 4 Interventional Results available

Post-Discharge Smoking Cessation Strategies: Helping HAND 4

NCT03603496
View directory record Official record
Conditions
Smoking Cessation
Interventions
Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Sep 30, 2026, 2:18 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)

NCT04827420
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Mi Quit Care
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 30, 2026, 2:18 AM EDT
Not listed Not applicable Interventional

Harm Reduction for Tobacco Smoking With Support of Tobacco-Replacing Electronic Nicotine Delivery Systems

NCT03962660
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
HaRTS-TRENDS, Standard Care (SC)
Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2019 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Phase 2 Interventional

Brief Intervention to Prevent Poor Psychosocial Outcomes in Living Donors

NCT01233700
View directory record Official record
Conditions
Living Donation
Interventions
Motivational Interviewing, Healthy Lifestyles Education
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 30, 2026, 2:18 AM EDT
Terminated Not applicable Interventional

Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

NCT00118534
View directory record Official record
Conditions
Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions
Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
11
States / cities
Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Patient Navigation-based Tobacco Harm Reduction Program Among Cancer Patients

NCT04972916
View directory record Official record
Conditions
Tobacco Use
Interventions
Patient navigation-based tobacco harm reduction intervention
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

A Comprehensive Smoking Cessation Intervention Duration Radiation for Upper Aerodigestive Cancers

NCT02188563
View directory record Official record
Conditions
Tobacco Use Disorder, Head and Neck Neoplasms, Thoracic Neoplasms, Radiation
Interventions
Comprehensive smoking cessation intervention, Enhanced usual care
Other · Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 105 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathe 2 Project 3: Comprehensive Chronic Care

NCT05382221
View directory record Official record
Conditions
Smoking Cessation, Smoking Abstinence
Interventions
Comprehensive Chronic Care, Standard Care
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
979 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

NCT02117947
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Behavioral Counseling, Self-help control
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization

NCT02099097
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
web-based video game (Quit IT), Questionnaires, Salvia sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Cancer Disparities Among Latinos in Texas

NCT01504919
View directory record Official record
Conditions
Psychosocial Problem
Interventions
Health Education, Questionnaires, Telephone Counseling Sessions, Nicotine Patches
Behavioral · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Sep 30, 2026, 2:18 AM EDT
Withdrawn Not applicable Interventional

Developing and Pilot Testing a Remote Smoking Cessation Digital Therapeutic for Individuals With Serious Mental Illness

NCT05031416
View directory record Official record
Conditions
Smoking Cessation
Interventions
LTQ
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Motivational Interviewing Compared to Psychoeducation for Smoking Precontemplators With SMI

NCT01982617
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Motivational Interviewing, Psychoeducation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Results available

Identifying Effective Treatment for Veterans Unwilling to Quit Smoking

NCT04061720
View directory record Official record
Conditions
Tobacco Dependence, Veterans
Interventions
Enhanced Chronic Care, Standard Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Results available

Smoking Cessation Using Motivational Therapy and Varenicline

NCT00701896
View directory record Official record
Conditions
Smoking, HIV Infections
Interventions
Varenicline tartrate, Nicotine Replacement Therapy, Biological Control, Motivational Interview
Drug · Other · Behavioral
Lead sponsor
Philip Diaz
Other
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Contingency Management for Smoking Cessation in the Homeless

NCT01736982
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Contingency Management, Standard of Care
Behavioral · Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Sep 30, 2026, 2:18 AM EDT
Active, not recruiting Not applicable Interventional

Post Acute Cardiac Event Smoking (PACES) Study

NCT03413423
View directory record Official record
Conditions
Acute Coronary Syndrome, Tobacco Use
Interventions
BAT-CS, Smoking Cessation and Health & Wellness
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Testing Methods of Self-persuasion Involving Cigarette Smoking

NCT02069483
View directory record Official record
Conditions
Smoking
Interventions
Motivational Interviewing, Tailored Feedback
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2014 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Varenicline Tartrate With Telephone-Based Counseling and/or Internet-Based Counseling in Helping Adults Stop Smoking

NCT00301145
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
smoking cessation intervention, varenicline, counseling intervention, internet-based intervention
Behavioral · Drug · Other
Lead sponsor
SRI International
Industry
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Menlo Park, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 19, 2013 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Phase 2 Interventional

Internet-Based Nonsmoking Program for Postpartum Women

NCT02602730
View directory record Official record
Conditions
Cigarette Smoking, Smoking, Tobacco
Interventions
Break the Chain, Clearing the Air
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
307 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent eReferral to Tobacco Quitline

NCT02997735
View directory record Official record
Conditions
Secondhand Smoke
Interventions
Quitline Delivered Treatment
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 30, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chicago Community Health Study

NCT04460417
View directory record Official record
Conditions
Smoking
Interventions
Enhanced Care, TAU
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 30, 2026, 2:18 AM EDT