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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:36 AM EDT

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Socket preservation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617
View directory record Official record
Conditions
Tooth Loss
Interventions
xenograft (BioOss Collagen)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Results available

An RCT Comparing Xenograft and Allograft for Ridge Preservation

NCT02330523
View directory record Official record
Conditions
Tooth Loss
Interventions
allograft + x-link collagen membrane, xenograft + non-x-link collagen
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison Between Primary and Secondary Flap Coverage in Extraction Sites: A Pilot Study

NCT03136913
View directory record Official record
Conditions
Loss of Teeth Due to Extraction
Interventions
Cytoplast® TXT-200, MinerOss® Cortical and Cancellous Chips (FDBA), Open Flap Technique, Closed Flap Technique
Device · Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 20, 2026, 5:36 AM EDT
Enrolling by invitation Not applicable Interventional

Effect of Age on PRF Quality; Assessed by Evaluating Healing Outcomes of ARP

NCT07023757
View directory record Official record
Conditions
Healing Wound
Interventions
Socket preservation
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Biotivity A-C Membrane Socket Preservation Study

NCT07091448
View directory record Official record
Conditions
Alveolar Ridge Preservation
Interventions
Amnion chorion membrane, Collagen membrane
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Socket Grafting for Alveolar Ridge Preservation

NCT01794806
View directory record Official record
Conditions
Atrophy of Edentulous Alveolar Ridge
Interventions
Tooth extraction and grafting with allograft, Tooth extraction
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 20, 2026, 5:36 AM EDT
Terminated Not applicable Interventional Results available

Ridge Preservation With Moldable Beta-tricalcium Phosphate Bone Substitute on Non-containable Non-Molar Extraction Sites

NCT03215667
View directory record Official record
Conditions
Alveolar Ridge Preservation, Dental Implants
Interventions
easy-graft CLASSIC (beta-Tricalcium Phosphate)
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 20, 2026, 5:36 AM EDT
Enrolling by invitation Not applicable Interventional

The Effectiveness of Carbonate Apatite Bone Graft for Alveolar Ridge Preservation

NCT07020650
View directory record Official record
Conditions
Healing Wound
Interventions
Socket preservation
Device
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Histologic Comparison of Healing After Tooth Extraction With Ridge Preservation Using Two Different Xenografts

NCT03769376
View directory record Official record
Conditions
Partial Edentulism
Interventions
Bio-Oss®, Salvin-Oss®
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 20, 2026, 5:36 AM EDT
Recruiting Not applicable Interventional

Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars

NCT07433322
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Ossix mineralized grafting immediately at extraction, Delayed grafting at implant placement
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed No phase listed Observational

Histologic Evaluation of Healing Following Tooth Extraction With Ridge Preservation Using NuOss XC and NuOss Particulate

NCT01391767
View directory record Official record
Conditions
Oral Ridge Preservation
Interventions
NuOss XC
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 8, 2013 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-PRF vs Collagen Membranes in Ridge Preservation

NCT07281053
View directory record Official record
Conditions
Ridge Preservation
Interventions
Barrier membrane for ridge preservation
Procedure
Lead sponsor
Center for Advanced Rejuvenation and Esthetics
Network
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft

NCT01431131
View directory record Official record
Conditions
Clinical Efficacy
Interventions
Intrasocket graft, Intrasocket plus facial overlay graft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 20, 2026, 5:36 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Vallomix Socket Preservation Study

NCT06472453
View directory record Official record
Conditions
Alveolar Ridge Augmentation
Interventions
Allograft/Xenograft, Allograft
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.

NCT03487718
View directory record Official record
Conditions
Alveolar Ridge Preservation, Tooth Extraction
Interventions
Leukocyte platelet rich fibrin plug + d-PTFE membrane, d-PTFE membrane
Biological · Device
Lead sponsor
Firas Al Yafi
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Oct 20, 2026, 5:36 AM EDT
Recruiting Not applicable Interventional

Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant

NCT06722482
View directory record Official record
Conditions
Ridge Preservation, Allografts, Extraction, Tooth, Xenograft
Interventions
FDBA, CEBX
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting

NCT05448040
View directory record Official record
Conditions
Socket Sealing, Free Gingival Graft, Collagen Membrane
Interventions
Socket preservation
Procedure
Lead sponsor
Universidade Salgado de Oliveira
Other
Eligibility
18 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporary Anchorage Devices for Ridge Preservation

NCT03205800
View directory record Official record
Conditions
Ridge Preservation
Interventions
Mini-screw
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Bone Material Comparison in Maxillary Sinus Augmentation

NCT04433117
View directory record Official record
Conditions
Alveolar Bone Resorption, Sequela, Tooth Extrusion
Interventions
Shefabone, Bio-Oss
Biological
Lead sponsor
Mohanad Al-Sabbagh
Other
Eligibility
20 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges

NCT03468998
View directory record Official record
Conditions
Alveolar Ridge Augmentation, Alveolar Ridge Preservation
Interventions
Socket Grafting with small particle allograft, Socket Grafting with large particle allograft, Lateral ridge augmentation with small particle allograft, Lateral ridge augmentation with large particle allograft
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and Quality of New Bone Formation in Grafted Extraction Sockets

NCT04133363
View directory record Official record
Conditions
Ridge Preservation
Interventions
Ridge preservation using L-PRF/FDBA layered technique, Ridge preservation using L-PRF/FDBA, Ridge preservation using L-PRF
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implant-Abutment Interface Design on Bone and Soft Tissue Levels Around Implants Placed Using Different Transcrestal Sinus Floor Elevation

NCT02953392
View directory record Official record
Conditions
Tooth Loss
Interventions
Anorganic Bovine Bone Graft Material, Collagen Membrane, Shelta Platform Switching Premium Implants, Shelta Platform Matching Premium Implants
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft

NCT05484492
View directory record Official record
Conditions
Alveolar Bone Resorption
Interventions
demineralized and mineralized combination putty bone allograft, calcium phosphosilicate putty alloplast graft
Biological
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 20, 2026, 5:36 AM EDT
Completed Phase 1 Interventional

Socket Preservation: A Clinical and Histological Study

NCT03422692
View directory record Official record
Conditions
Alveolar Ridge Augmentations
Interventions
BioXclude amnion-chorion membrane, Mem-Lok collagenous membrane
Biological
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 20, 2026, 5:36 AM EDT