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Showing 25–47 of 23 matching trials from the live ClinicalTrials.gov search.
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Conditions
Insulin Resistance, Hyperinsulinemia, Metabolic Dysfunction Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Prediabetic State, Obesity
Interventions
Insulin human, Octreotide Acetate, Glucagon, Growth Hormone, Human, 20% D-glucose (aq), [6,6-2H2] D-glucose, [1-13C1] sodium acetate, Nestle BOOST Plus, KIND Bar, Harvard Apparatus PHD ULTRA CP syringe pump, Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer
Drug · Diagnostic Test · Dietary Supplement + 1 more
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York
Not listed Not applicable Interventional Accepts healthy volunteers

Salt and HMB Study

NCT05515900
Conditions
Blood Pressure
Interventions
Sodium, HMB, Placebo
Dietary Supplement · Other
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Vitamin D Deficiency
Interventions
Redoxon VI, placebo
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
55 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Corvallis, Oregon
Conditions
Heart Failure
Interventions
Sodium reduction, omega 3 and lycopene supplements, rice bran oil capsules, Generic dietary feedback from
Behavioral · Dietary Supplement
Lead sponsor
Terry Lennie
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Lexington, Kentucky • Louisville, Kentucky
Conditions
Obesity &Amp; Overweight
Interventions
Cardiovascular Exercise, Butyrate
Behavioral · Dietary Supplement
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2, Very Long Chain Acyl Coa Dehydrogenase Deficiency, Trifunctional Protein Deficiency
Interventions
Nutritional Ketone Supplement, Isocaloric Placebo Supplement
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Completed Phase 1 Interventional Accepts healthy volunteers

Nutritional and Contractile Regulation of Muscle Growth

NCT00891696
Conditions
Sarcopenia
Interventions
Rapamycin, Amino acid supplementation, Low-intensity resistance exercise, Sodium nitroprusside, Blood flow restriction cuff
Drug · Other · Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Galveston, Texas
Completed Not applicable Interventional

Food As Medicine for Heart Failure

NCT04847973
Conditions
Heart Failure, Malnutrition
Interventions
Medically-Tailored Meals (MTMs), Protein supplementation shakes
Other · Dietary Supplement
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Osteoporosis, Inflammation
Interventions
Yogurt Intervention
Other
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
50 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lawrence, Massachusetts
Conditions
Relapsed or Refractory Lymphoproliferative Malignancies, Hodgkin's Lymphoma, Peripheral T-cell Lymphoma, B-cell Lymphoma, Waldenstrom's Macroglobulinemia
Interventions
Pralatrexate Injection, Gemcitabine Hydrochloride, Vitamin B12, Folic Acid
Drug · Dietary Supplement
Lead sponsor
Acrotech Biopharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Los Angeles, California • Stanford, California • Denver, Colorado + 11 more
Completed Not applicable Interventional Accepts healthy volunteers

Nitrite Supplementation for Improving Physiological Function in Older Adults

NCT02393742
Conditions
Ageing
Interventions
Sodium nitrite, Placebo
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
60 Years to 79 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boulder, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Ester And Salt (KEAS) in Older Adults

NCT06868719
Conditions
Salt; Excess, Hypertension, Aging, Inflammation, Blood Pressure
Interventions
No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome

NCT05546814
Conditions
Preterm Birth
Interventions
Sodium algorithm
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
25 Weeks to 30 Weeks
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin

NCT03477825
Conditions
Sebum Production, Stool Microbiome, Transepidermal Water Loss, Facial Brrightness, Erythema, Wrinkles, Facial Shine
Interventions
Placebo Oral Tablet, Rubia Cordifolia, Triphala
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Potassium Bicarbonate Supplementation on Bone and Muscle in Older Adults

NCT00357214
Conditions
Osteoporosis, Sarcopenia
Interventions
Potassium Bicarbonate, Sodium Bicarbonate, Potassium Chloride, placebo (microcrystalline cellulose)
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

Ketone Supplementation in Individuals With PTSD

NCT04083352
Conditions
PTSD, Ketosis
Interventions
Pruvit Ketomax Ketone Salt, Placebo
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Toxicity, Radiation Toxicity
Interventions
Short Chain Fatty Acid, Tapioca Flour
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Potassium Supplementation Study

NCT05887622
Conditions
Cardiovascular Health, Cardiovascular Risk Factor
Interventions
Potassium chloride supplement, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Preterm Infants
Interventions
selenium and sodium selenate supplementation, selenium and sodium selenite supplementation, Without selenium and sodium selenate supplementation, Without selenium and sodium selenite supplementation
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1993
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Accepts healthy volunteers Results available

Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

NCT04021355
Conditions
Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
Interventions
Oral sodium supplementation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 45 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Osteoarthritis
Interventions
Ensure
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Conditions
Cardiac Surgery, Cardiopulmonary Bypass
Interventions
AT-III (Human), Placebo
Biological · Other
Lead sponsor
Grifols Therapeutics LLC
Industry
Eligibility
18 Years and older
Enrollment
425 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
41
States / cities
Orange, California • San Francisco, California • Stanford, California + 36 more
Completed Phase 1 Interventional Accepts healthy volunteers

Acid-Base Compensation in Chronic Kidney Disease

NCT02427594
Conditions
Chronic Kidney Disease
Interventions
Sodium bicarbonate, Controlled diet
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
22 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina