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ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:34 AM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Soft Tissue Mobilization Clear all
Completed Not applicable Interventional

A Comparison of Manual Physical Therapy and Corticosteroid Injections for Knee Osteoarthritis

NCT01427153
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Orthopaedic manual physical therapy, Corticosteroid Injection
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
38 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Differences in Elbow Stiffness Comparing Massage to Stretching in Tennis Players

NCT07060521
View directory record Official record
Conditions
Tendon Stiffness, Lateral Elbow Tendinopathy
Interventions
soft tissue mobilization, Self Stretching
Other
Lead sponsor
University of Dayton
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Integrating Chiropractic Care and Mind-Body Training for the Treatment of Nonspecific Chronic Neck Pain

NCT06523036
View directory record Official record
Conditions
Neck Pain, Nurse-Patient Relations
Interventions
Combined chiropractic care and Tai Chi
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 19, 2026, 11:34 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Photobiomodulation for Myofascial Pelvic Pain

NCT05926752
View directory record Official record
Conditions
Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome, Myalgia of Pelvic Floor
Interventions
SoLá therapy, Pelvic floor physical therapy
Device · Other
Lead sponsor
Orlando VA Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Physical Therapy Versus Steroid Injection for Shoulder Impingement Syndrome

NCT01190891
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Manual Physical Therapy, Corticosteroid Injection
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Apr 29, 2016 · Synced Oct 19, 2026, 11:34 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures

NCT05033938
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Early Mobilization Protocol, Late Mobilization Protocol
Procedure
Lead sponsor
Robert Wood Johnson Barnabas Health
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder

NCT03300297
View directory record Official record
Conditions
Temporomandibular Disorder
Interventions
Cervical Spine Thrust Joint Manipulation, Cervical Spine Sham Manipulation, Home Program, Suboccipital Release
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Peoria, Illinois • Washington, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Postural Education or Corrective Exercise on Forward Head Posture

NCT05321654
View directory record Official record
Conditions
Postural; Defect
Interventions
Education for Behavior Modification, Corrective Exercise Program
Behavioral
Lead sponsor
Liberty University
Other
Eligibility
18 Years to 29 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of IASTM and Proprioception

NCT03023943
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Instrument Assisted Soft Tissue Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 10, 2020 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Does Physical Therapy Prevent Total Knee Arthroplasty in Patients With End Stage Osteoarthritis

NCT02377102
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional

A Trial Comparing Mechanical Diagnosis and Treatment to Manual Therapy

NCT03049644
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
Mechanical Diagnosis and Therapy, Manual Therapy
Procedure
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 19, 2026, 11:34 AM EDT
Not yet recruiting Not applicable Interventional

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786
View directory record Official record
Conditions
Spine, Low Back Pain, Neck Pain
Interventions
Massage, Talk-based therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Education/Exercise and Chiropractic for Chronic Back Pain

NCT00561652
View directory record Official record
Conditions
Low Back Pain
Interventions
Education & Exercise, Chiropractic treatment (plus Education & Exercise)
Behavioral · Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2015 · Synced Oct 19, 2026, 11:34 AM EDT
Recruiting Not applicable Interventional

Comparing the Effectiveness of the 'Think in Nerve Length and Layers' (TINLL) Approach to Traditional Treatment for Patients With Lateral Elbow Pain.

NCT07385677
View directory record Official record
Conditions
Lateral Elbow Tendinopathy (Tennis Elbow)
Interventions
TINLL techniques for relieving radial nerve tension, Traditional techniques to stretch and strengthen muscles
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects

NCT02015390
View directory record Official record
Conditions
Segmental Long Bone Defects
Interventions
Autogenous RIA bone grafting, Allogeneic bone grafting
Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Phase 2Phase 3 Interventional

Chiropractic and Exercise for Low Back Pain in Adolescents

NCT01096628
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic + Exercise, Exercise
Other
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
12 Years to 18 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Bloomington, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 31, 2014 · Synced Oct 19, 2026, 11:34 AM EDT
Not listed Not applicable Interventional

The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain

NCT04851730
View directory record Official record
Conditions
Pelvic Pain, Chronic Pain, Muscle Tightness
Interventions
Orthopedic Physical Therapy Intervention, Dry Needling
Procedure · Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Lee's Summit, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Low Back Pain

NCT00269321
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Manual treatment + home exercise (procedure+behavior), Supervised rehabilitative exercise+home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 28, 2013 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment

NCT04162262
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Instrumental-assisted soft tissue mobilization (IASTM), High-Load Strength Training, Plantar Flexor and Gastrocnemius Stretching
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 60 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 19, 2026, 11:34 AM EDT
Withdrawn Not applicable Interventional

Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis

NCT04073212
View directory record Official record
Conditions
Bicep Tendinitis, Biceps; Tenosynovitis, Bicipital Tendinitis, Left Shoulder, Bicipital Tendinitis, Right Shoulder, Bicipital Tendinitis, Unspecified Shoulder, Biceps Tendon Disorder
Interventions
Dry Needling, Heavy Slow Load Exercise, Rotator cuff and scapular stabilization exercise program, Soft tissue mobilization
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Oct 19, 2026, 11:34 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Dry Needling and STM on Pain Management for Anterior Cruciate Ligament Reconstruction (ACLR)

NCT03506685
View directory record Official record
Conditions
Pain and Anterior Cruciate Ligament Reconstruction
Interventions
Dry needling and STM
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 19, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soft Tissue Mobilization for Lumbopelvic Pain in the Third Trimester of Pregnancy

NCT03433404
View directory record Official record
Conditions
Low Back Pain, Pregnancy
Interventions
Soft Tissue Mobilization, Soft Tissue Massage
Procedure
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 19, 2026, 11:34 AM EDT
Terminated No phase listed Observational

The Role of Mechanical Diagnosis and Therapy in the Management of Concussion

NCT05859815
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
Physical Therapy
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
13 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Orland Park, Illinois • Niagara Falls, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 19, 2026, 11:34 AM EDT