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Showing 25–48 of 223 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

DD T2 Daily Disposable Registration Trial

NCT03305770
Conditions
Myopia, Refractive Errors
Interventions
verofilcon A contact lenses, delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Visual Performance of Two Types of Cosmetic Contact Lenses

NCT04534764
Conditions
Visual Acuity
Interventions
etafilcon A with cosmetic pattern, 1-Day Acuvue DEFINE Vivid Style
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Maitland, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Orthokeratology in Myopia Control

NCT03465748
Conditions
Myopia
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 13 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear

NCT01015768
Conditions
Contact Lens-induced Corneal Fluorescein Staining
Interventions
ReNu Multiplus multipurpose disinfecting solution, Control
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fullerton, California
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, Multi-purpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Maitland, Florida • Bloomington, Illinois • Memphis, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Objective Testing of Tear Film Stability

NCT00789529
Conditions
Contact Lens Solutions
Interventions
Opti-Free® RepleniSH® MPDS, ReNu MultiPlus®
Device
Lead sponsor
Manhattan Vision Associates
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Conditions
Astigmatism, Myopia
Interventions
Lens A ( comfilcon A), Lens B ( lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
New York, New York • Granville, Ohio • Corpus Christi, Texas
Conditions
Corneal Diseases
Interventions
Not listed
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
769 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
4
States / cities
La Jolla, California • San Diego, California • Greenwood Village, Colorado + 1 more
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
15
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 11 more
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

NCT04840563
Conditions
Contact Lens Wear
Interventions
kalifilcon A daily disposable spherical soft contact lens, Dailies Total1 (delefilcon A) daily disposable spherical soft contact lens, Precision1 (verofilcon A) daily disposable spherical soft contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Rochester, New York
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light

NCT05344560
Conditions
Visual Acuity
Interventions
soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Completed No phase listed Observational

Air Optix Daily Wear Contact Lenses

NCT05827224
Conditions
Refractive Errors
Interventions
Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive, Comfilcon A spherical soft contact lenses, Comfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Timeline
2023 – 2024
U.S. locations
5
States / cities
Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more
Conditions
Myopia
Interventions
Delefilcon A contact lenses, Narafilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Photophobia, Visual Impairment, Low Vision
Interventions
Acuvue Oasys with Transitions
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Davie, Florida
Conditions
Contact Lenses, Extended-Wear
Interventions
Silicone Hydrogel Soft Contact Lenses
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 38 Years
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Refractive Errors, Astigmatism
Interventions
Verofilcon A toric contact lenses, Stenfilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
6
States / cities
Maitland, Florida • Pittsburg, Kansas • Sterling Heights, Michigan + 3 more
Conditions
Myopia, Hyperopia
Interventions
narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
8 Years and older
Enrollment
1,171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
37
States / cities
Campbell, California • Fullerton, California • Huntington Beach, California + 29 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design Validation of Senofilcon A With New UV-blocking Additive

NCT03707821
Conditions
Visual Acuity
Interventions
senofilcon A TEST Lens, senofilcon A CONTROL Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
10
States / cities
Cupertino, California • Maitland, Florida • Tallahassee, Florida + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Toric Contact Lens Performance Study

NCT03546647
Conditions
Astigmatism
Interventions
Dailies Aqua Comfort Plus Toric, Dailies Aqua Comfort Plus Sphere
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas