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Showing 1–24 of 106 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Soft tissue massage Clear all
Completed Phase 2 Interventional

Home Based Massage and Relaxation for Sickle Cell Pain

NCT00066079
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
massage, relaxation
Procedure · Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
15 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Los Angeles, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brainwave Activity Response on Common Physical Therapy Intervention

NCT04542707
View directory record Official record
Conditions
Pain
Interventions
joint manipulation, Exercise, Soft tissue massage
Procedure · Device
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 1Phase 2 Interventional

Therapeutic Massage for Generalized Anxiety Disorder

NCT00515242
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
massage, thermotherapy, relaxing environment
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 70 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Impact of Massage Therapy on the Quality of Life of Hospice Patients

NCT02880202
View directory record Official record
Conditions
Pain, Anxiety, Depression, Quality of Life
Interventions
Massage Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 25, 2018 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2 Interventional

Spinal Manipulation for Treatment of Chronic Headaches

NCT00246350
View directory record Official record
Conditions
Headache Disorders
Interventions
massage, Spinal manipulation
Procedure
Lead sponsor
University of Western States
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 21, 2010 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2 Interventional

Massage Therapy for Breast Cancer Treatment-Related Swelling of the Arms

NCT00058851
View directory record Official record
Conditions
Lymphedema
Interventions
Manual lymph drainage, Combined physiotherapy, Compression bandaging
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
Not listed
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 18, 2009 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Effects of Massage Therapy and Kinesthetic Stimulation on Pre-Term Infants

NCT00661791
View directory record Official record
Conditions
Prematurity
Interventions
Massage therapy without exercise, Massage therapy with exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
28 Weeks to 32 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2008 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2 Interventional

Physical CAM Therapies for Chronic Low Back Pain

NCT00065975
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
massage therapy, chiropractic, acupuncture
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
20 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Sep 1, 2026, 11:57 PM EDT
Terminated Not applicable Interventional

Imaging Lymphatic/Cerebrospinal Fluid (CSF) Drainage From the Head and Neck in Persons With Traumatic Brain Injury: Demonstration of Feasibility and Evaluation of Manual Therapy to Improve Drainage and Facilitate Cognitive Recovery

NCT05129514
View directory record Official record
Conditions
Trauma, Brain, Neuroinflammation
Interventions
Manual Lymphatic Drainage (MLD)
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 1, 2026, 11:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Investigating Proximal Muscle Strength Effects by Incorporating Proximal Muscle Lengthening

NCT05710757
View directory record Official record
Conditions
Proximal Muscle Strength, Proximal Muscle Lengthening
Interventions
myofascial release, blood flow restriction
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2Phase 3 Interventional

Effect of Massage on Chronic Low Back Pain

NCT00371384
View directory record Official record
Conditions
Chronic Low Back Pain (Non-specific, Uncomplicated)
Interventions
massage
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 64 Years
Enrollment
399 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery

NCT04233385
View directory record Official record
Conditions
Breast Cancer, Mastectomy; Lymphedema, Pain, Shoulder, Mobility Limitation
Interventions
Myofascial Massage, Light Touch
Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2Phase 3 Interventional

Enhancing the Effectiveness of Physical Therapy for People With Knee Osteoarthritis

NCT01314183
View directory record Official record
Conditions
Osteoarthritis
Interventions
Exercise, manual therapy
Other
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Federal
Eligibility
40 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • San Antonio, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 2 Interventional

Massage Therapy in Treating Patients With Cancer Pain

NCT00082290
View directory record Official record
Conditions
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
massage therapy, visit with a volunteer, period of quiet time, questionaire about pain
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 120 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2015 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 1Phase 2 Interventional

A Randomized Study of Polarity or Massage Therapy to Reduce Fatigue in Breast Cancer Patients During Radiation Therapy

NCT00288795
View directory record Official record
Conditions
Fatigue
Interventions
Massage Therapy, Polarity Therapy
Other
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 30, 2011 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms Underlying Local and Systemic Effects of Massage

NCT04131712
View directory record Official record
Conditions
Muscle Atrophy
Interventions
Massage
Other
Lead sponsor
Esther Dupont-Versteegden
Other
Eligibility
18 Years to 30 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Phase 1Phase 2 Interventional

Evaluating Therapeutic Massage for Chronic Neck Pain

NCT00065416
View directory record Official record
Conditions
Neck Pain, Cervicalgia
Interventions
massage
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
20 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study

NCT01842737
View directory record Official record
Conditions
Low Back Pain
Interventions
Spinal treatment, Massage
Procedure
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Massage Therapy Versus Music Therapy Pilot Study

NCT02227680
View directory record Official record
Conditions
ALL
Interventions
Music Therapy, Massage Therapy
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2015 · Synced Sep 1, 2026, 11:57 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches

NCT04520425
View directory record Official record
Conditions
Chronic Migraine, Headache
Interventions
Osteopathic manipulative therapy
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 1, 2026, 11:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Pilot Study on Energy Therapy or Massage to Reduce Fatigue

NCT02758756
View directory record Official record
Conditions
Fatigue
Interventions
Massage, Reiki
Other
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 1, 2026, 11:57 PM EDT
Terminated Not applicable Interventional

Massage Therapy for Self-efficacy in LVAD Recipients

NCT04018508
View directory record Official record
Conditions
Heart Failure
Interventions
Massage
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 1, 2026, 11:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Massage Therapy in Premature Neonates

NCT06163586
View directory record Official record
Conditions
Neonatal Prematurity, Massage Therapy
Interventions
Neonatal Touch and Massage Therapy
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 1, 2026, 11:57 PM EDT