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Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Soterix tDCS device Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation

NCT07635017
View directory record Official record
Conditions
Cortical Excitability, Healthy, TMS, Menstrual Cycle, Menopause
Interventions
Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS
Device
Lead sponsor
Carnegie Mellon University
Other
Eligibility
18 Years to 40 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INSIGHT, A Comprehensive, Multidisciplinary Brain Training System

NCT02780739
View directory record Official record
Conditions
Cognitive Ability, General
Interventions
Cognitive Training - 48 sessions, Fitness, Active Control, active tDCS, sham tDCS, Cognitive Training - 20 sessions
Behavioral · Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 44 Years
Enrollment
521 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2016 · Synced Sep 12, 2026, 4:29 PM EDT
Not listed Not applicable Interventional

Transcranial Direct Current Stimulation for the Treatment of Delirium

NCT03256500
View directory record Official record
Conditions
Delirium, Confusion
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
North Florida/South Georgia Veterans Health System
Other
Eligibility
21 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Sep 12, 2026, 4:29 PM EDT
Recruiting Phase 2Phase 3 Interventional

Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation

NCT07688551
View directory record Official record
Conditions
Aphasia, Broca's Aphasia
Interventions
tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 12, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

NCT07246993
View directory record Official record
Conditions
Persistent Post Concussion Syndrome, Mild Traumatic Brain Injury
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Phase 2Phase 3 Interventional

Investigating tDCS as a Treatment for Unipolar and Bipolar Depression

NCT01562184
View directory record Official record
Conditions
Unipolar Depression, Bipolar Depression
Interventions
Sham tDCS device, Soterix tDCS device
Device
Lead sponsor
The University of New South Wales
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
5
States / cities
Atlanta, Georgia • Towson, Maryland • Cherry Hill, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Pediatric Teleneuromodulation

NCT05071586
View directory record Official record
Conditions
Cerebral Palsy (CP)
Interventions
Soterix 1x1 tDCS LTE Stimulator Device Model 1401
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
8 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Phase 2 Interventional Results available

Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)

NCT05615922
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Transcranial Direct Current Stimulation (tDCS), Word-Naming Activity
Device · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional

Neurostimulation for Cognitive Enhancement in Alzheimer's Disease

NCT04404153
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver active tDCS., tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver sham tDCS.
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 12, 2026, 4:29 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task

NCT02840214
View directory record Official record
Conditions
Fatigue
Interventions
transcranial direct current stimulation, sham tDCS
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Combined Effect of Transcranial Direct Current Stimulation (tDCS) and Physical Activity on Gait and Functional Mobility in Participants With Multiple Sclerosis

NCT03658668
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
active tDCS, sham tDCS, Physical Activity (PA)
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 12, 2026, 4:29 PM EDT
Withdrawn Not applicable Interventional

Open Label Extension Study of tDCS Plus Guided Imagery for Women With Chronic Pelvic Pain (CPP)

NCT04252040
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Active tDCS with guided imagery
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 64 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 22, 2022 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure

NCT04236284
View directory record Official record
Conditions
Chronic Pain, PTSD
Interventions
Home-based tDCS, Prolonged Exposure Therapy
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults

NCT05583578
View directory record Official record
Conditions
Mobility Limitation, Aging
Interventions
Home-based mobility testing and active tDCS, Sham tDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
70 Years to 95 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 12, 2026, 4:29 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cerebral Excitability and Cognitive Performance

NCT03807934
View directory record Official record
Conditions
Cognitive Change
Interventions
Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 65 Years
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

tDCS and Glucose Uptake in Leg Muscles

NCT04016844
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
transcranial direct current stimulation or SHAM
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 12, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD)

NCT06236711
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
tDCS
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 12, 2026, 4:29 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation

NCT06522685
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
Device
Lead sponsor
Morgan State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 12, 2026, 4:29 PM EDT
Recruiting Phase 2 Interventional

Transcranial Direct Current Stimulation for Post-stroke Fatigue

NCT05816603
View directory record Official record
Conditions
Fatigue, Stroke Rehabilitaion
Interventions
Real Soterix Mini-CT tDCS stimulator, Sham Soterix Mini-CT tDCS stimulator
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 12, 2026, 4:29 PM EDT
Terminated Phase 1Phase 2 Interventional

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety
Interventions
transcranial direct current stimulation using a Soterix mini-CT device
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 28 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis

NCT03747640
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Self Transcranial Direct Current Stimulation (tDCS), mindfulness-based meditation, Sham Self Transcranial Direct Current Stimulation (tDCS), sham meditation
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Post-stroke Fatigue, Inflammation, tDCS

NCT05330988
View directory record Official record
Conditions
Stroke, Fatigue, Chronic Stroke, Stroke Sequelae
Interventions
anodal transcranial direct current stimulation (a-tDCS), sham stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 12, 2026, 4:29 PM EDT
Withdrawn Not applicable Interventional

tDCS for the Management of Chronic Visceral Pain in Patients With Chronic Pancreatitis

NCT01857492
View directory record Official record
Conditions
Chronic Pancreatitis, Pain
Interventions
tDCS, Meditation
Device · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2015 · Synced Sep 12, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

TOlerability of Transcranial Direct Current Stimulation in Pediatric Stroke Survivors

NCT05812794
View directory record Official record
Conditions
Childhood Stroke
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
5 Years to 19 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Sep 12, 2026, 4:29 PM EDT