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ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:26 PM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Soy Isolate Clear all
Completed Phase 2 Interventional

Soy Protein Supplement in Preventing Prostate Cancer in Patients With Elevated Prostate-Specific Antigen Levels

NCT00031746
View directory record Official record
Conditions
Prostate Cancer
Interventions
soy protein isolate, casein proteins
Dietary Supplement
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
50 Years and older · Male only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Syracuse, New York • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Soy and Isoflavones Effect on Bone

NCT00668447
View directory record Official record
Conditions
Osteoporosis
Interventions
Soy Isolate, Control protein, Novasoy isoflavones, Placebo tablets
Dietary Supplement
Lead sponsor
United States Department of Agriculture (USDA)
Federal
Eligibility
65 Years and older · Female only
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2008 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional

Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight

NCT00343434
View directory record Official record
Conditions
Breast Cancer, Obesity
Interventions
behavioral dietary intervention, exercise intervention, soy isoflavones, soy protein isolate, counseling intervention, educational intervention, psychosocial assessment and care, quality-of-life assessment
Behavioral · Dietary Supplement · Other + 1 more
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 120 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Oct 17, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prandial Metabolic Phenotyping in Sarcopenic Older Adults Comparing Plant Based and Whey Based Protein

NCT06628349
View directory record Official record
Conditions
Protein Metabolism
Interventions
Whey Protein Isolate 90%, Soy Protein Isolate (90% Protein), Organic Pea Protein Isolate, Placebo (Water)
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
50 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional

High-protein Oral Supplement Improves Normalized Protein Catabolic Rate and Inflammation Markers

NCT05227755
View directory record Official record
Conditions
Renal Failure, Chronic Kidney Disease Requiring Chronic Dialysis
Interventions
Soy protein isolate, Whey protein isolate
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 17, 2026, 10:26 PM EDT
Terminated Not applicable Interventional

Isoflavones in Treating Women Who Have Breast Cancer and Are Planning to Undergo Mastectomy or Lumpectomy

NCT00036686
View directory record Official record
Conditions
Breast Cancer
Interventions
Soy protein isolate, Placebo
Dietary Supplement · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
7
States / cities
Phoenix, Arizona • Tampa, Florida • Savannah, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2012 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 3 Interventional

Diet and PSA Levels in Patients With Prostate Cancer

NCT00003367
View directory record Official record
Conditions
Prostate Cancer
Interventions
green tea, soy protein isolate, vitamin E
Dietary Supplement
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2002
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2013 · Synced Oct 17, 2026, 10:26 PM EDT
Withdrawn Not applicable Interventional

Effect of Soy Intake on Cardiovascular Disease Biomarkers in Subclinical Hypothyroid Participants

NCT02024906
View directory record Official record
Conditions
Cardiovascular Disease, Subclinical Hypothyroid
Interventions
soy protein isolate (SPI), milk protein isolate (MPI)
Dietary Supplement
Lead sponsor
Jill Hamilton-Reeves, PhD RD LD
Other
Eligibility
25 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake

NCT03154606
View directory record Official record
Conditions
Appetitive Behavior
Interventions
Micellar Casein (#1), Micellar Casein (#2), Calcium Caseinate, Sodium Caseinate, Milk Protein Isolate, Pure Protein Blend, Whey Protein Isolate, Native Whey Protein Isolate, Soy Protein, Pea Protein, Native Whey: Micellar Casein (50:50) blend, Carbohydrate Control
Other
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of a Soy-based Meal Replacement Weight Loss Intervention to Impact Ectopic Fat

NCT01298817
View directory record Official record
Conditions
Abdominal Obesity
Interventions
Medifast meal replacement products
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study Evaluating the Digestibility of Serum-Derived Bovine Immunoglobulin Protein Isolate in Healthy Adults

NCT02017405
View directory record Official record
Conditions
Healthy
Interventions
Serum-derived bovine immunoglobulin protein isolate (SBI), Matching Placebo
Other
Lead sponsor
Entera Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Cary, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements

NCT03868631
View directory record Official record
Conditions
Skeletal Muscle Growth
Interventions
Whey protein supplement, Soy protein supplement
Dietary Supplement
Lead sponsor
Point Loma Nazarene University
Other
Eligibility
18 Years to 35 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota

NCT04018066
View directory record Official record
Conditions
Mechanisms, Defense
Interventions
GP-SPI
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 35 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 2Phase 3 Interventional

Soy Protein in Preventing Recurrent Cancer in Patients Who Have Undergone Surgery for Stage II Prostate Cancer

NCT00765479
View directory record Official record
Conditions
Prostate Cancer
Interventions
soy protein isolate, placebo
Dietary Supplement · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years to 75 Years · Male only
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2013 · Synced Oct 17, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional

Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

NCT06858449
View directory record Official record
Conditions
Cancer, Breast Cancer
Interventions
Whey protein (20 grams), Whey protein (60 grams)
Dietary Supplement
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
20 Years to 89 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 2 Interventional

Soy Supplements in Treating Patients Undergoing Surgery for Localized Prostate Cancer

NCT00345813
View directory record Official record
Conditions
Prostate Cancer
Interventions
soy isoflavones, soy protein isolate, placebo
Dietary Supplement · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2018 · Synced Oct 17, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional

EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer

NCT07704476
View directory record Official record
Conditions
Cancer, Breast Cancer
Interventions
Whey protein (60 grams), No protein
Dietary Supplement · Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
20 Years to 89 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Results available

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy

NCT01828593
View directory record Official record
Conditions
HIV-associated Enteropathy
Interventions
Serum-derived bovine immunoglobulin protein isolate (SBI), Placebo
Other
Lead sponsor
Entera Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
10
States / cities
Los Angeles, California • Sacramento, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 17, 2026, 10:26 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Isoflavones for Promoting Calcium Absorption and Preventing Bone Loss in Post Menopausal Women

NCT00244907
View directory record Official record
Conditions
Osteoporosis, Osteopenia
Interventions
Genistein vs Risedronate
Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Phase 2 Interventional

Isoflavones and Radiation Therapy in Treating Patients With Localized Prostate Cancer

NCT00243048
View directory record Official record
Conditions
Prostate Cancer
Interventions
soy protein isolate, radiation therapy
Dietary Supplement · Radiation
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2013 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Effect of Whey and Soy Protein on the Absorption of Pomegranate Polyphenols in the Human Body

NCT02233478
View directory record Official record
Conditions
Healthy
Interventions
Pomegranate Juice, Soybean Flour Protein, Soy Isolate Protein
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Oct 17, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study

NCT00942513
View directory record Official record
Conditions
Substrate Absorption, Substrate Oxidation, Glucose Regulation
Interventions
trt 1, trt 2, trt 3, trt 4, trt 5, trt 6, trt 7
Other
Lead sponsor
United States Department of Agriculture (USDA)
Federal
Eligibility
25 Years to 65 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2011 · Synced Oct 17, 2026, 10:26 PM EDT
Terminated Not applicable Interventional

To Evaluate SBI in the Dietary Management of Mild to Moderate Crohn's Disease

NCT02649075
View directory record Official record
Conditions
Crohn's Disease
Interventions
Serum-derived Bovine Immunoglobulin / Protein Isolate, Placebo
Other
Lead sponsor
Entera Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
7
States / cities
North Little Rock, Arkansas • Hollywood, Florida • Winter Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 17, 2026, 10:26 PM EDT