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ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:46 PM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spatial Frequency Domain Imaging Clear all
Not yet recruiting No phase listed Observational

Assessment Of Burn Severity and Extent Spatial Frequency Domain Imaging

NCT06921421
View directory record Official record
Conditions
Burn, Burn Injury
Interventions
Spatial Frequency Domain Imaging
Diagnostic Test
Lead sponsor
The Metis Foundation
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 2, 2026, 3:46 PM EDT
Enrolling by invitation No phase listed Observational

Analysis of Lung Cancer Tissue With Spatial Frequency Domain Imaging

NCT06549088
View directory record Official record
Conditions
Lung Diseases, Cancer, Lung
Interventions
Spatial Frequency Domain Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

Effect of Modulating Gamma Oscillations Using tACS

NCT03412604
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial Alternating Current Stimulation (tACS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Tissue Oxygenation Measurement Using Multimodal Devices

NCT05784103
View directory record Official record
Conditions
Oxygen Saturation
Interventions
Clarifi Modulum, Perimed PeriFlux 5000, Apple Watch Oxygen Sensor, Innovo iP 900AP
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus

NCT00329524
View directory record Official record
Conditions
Tinnitus
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
19 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 3, 2015 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

Optical Coherence Tomography (OCT) Based Screening of Esophagus and Gastroesophageal Junction

NCT01401699
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Optical Frequency Domain Imaging (OFDI)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults

NCT01439035
View directory record Official record
Conditions
Celiac Disease
Interventions
MGH OFDI Imaging
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
7 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

Optical Frequency Domain Imaging (OFDI) and Vascular Healing After Stent Placement

NCT01794949
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Resolute Integrity stent
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 2, 2026, 3:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System

NCT02947971
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Experimental OFDI Imaging
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Phase 1Phase 2 Interventional

Gamma Induction for Alzheimer's Disease

NCT03880240
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
Transcranial Alternating Current Stimulation (tACS), Sham Transcranial Alternating Current Stimulation
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 2, 2026, 3:46 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule

NCT02202681
View directory record Official record
Conditions
Celiac Disease, Healthy
Interventions
OFDI Capsule
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional

Optical Frequency Domain Imaging for Non-melanoma Skin Cancers

NCT01662713
View directory record Official record
Conditions
Non-Melanoma Skin Cancer (NMSC)
Interventions
OFDI
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Sep 2, 2026, 3:46 PM EDT
Terminated No phase listed Observational Results available

Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients

NCT04583163
View directory record Official record
Conditions
Cerebral Aneurysm, Stroke, Vasospasm, Cerebral, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
Interventions
Transcranial Doppler
Diagnostic Test
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
3 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Sep 2, 2026, 3:46 PM EDT
Completed No phase listed Observational

Pilot Study to Evaluate Optical Frequency Domain Imaging for Diagnosis of Central Airway Disease

NCT01396603
View directory record Official record
Conditions
Squamous Cell Lung Cancer, Lung Cancer
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

tACS for Amyloid-β Reduction in Alzheimer's Disease

NCT03290326
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial Alternating Current Stimulation (tACS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Sep 2, 2026, 3:46 PM EDT
Completed No phase listed Observational

Feasibility of Orbital Atherectomy System in Calcified Bifurcation Lesion

NCT03058510
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Frequency domain optical coherence tomography
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 2, 2026, 3:46 PM EDT
Enrolling by invitation Not applicable Interventional

Pilot TMS in Mild TBI

NCT06999304
View directory record Official record
Conditions
Persistent Post Concussive Headache, Mild Traumatic Brain Injury
Interventions
Intermittent theta burst stimulation
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 2, 2026, 3:46 PM EDT
Withdrawn No phase listed Observational

Optical Frequency Domain Imaging (OFDI) in Dermatology

NCT01438047
View directory record Official record
Conditions
Port Wine Stain
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2014 · Synced Sep 2, 2026, 3:46 PM EDT
Withdrawn No phase listed Observational

Predicting Breast Flap Necrosis by Spatial Frequency Domain Imaging

NCT02273076
View directory record Official record
Conditions
Disorders of Skin Grafts and Flaps
Interventions
Spatial Frequency Domain Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 2, 2026, 3:46 PM EDT
Terminated Not applicable Interventional Results available

Individualized Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations

NCT05319080
View directory record Official record
Conditions
Schizophrenia and Related Disorders
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
Columbia University
Other
Eligibility
22 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 2, 2026, 3:46 PM EDT
Recruiting No phase listed Observational

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

NCT04166526
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
FDNIRS-DCS, MRI
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 2, 2026, 3:46 PM EDT
Recruiting Not applicable Interventional

A Study Comparing Two Optical Coherence Tomography Devices in People With Ocular Tumors

NCT07449195
View directory record Official record
Conditions
Ocular Tumor
Interventions
Intalight Dream OCT, Heidelberg Spectralis OCT
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 2, 2026, 3:46 PM EDT
Completed Not applicable Interventional Results available

Optical Frequency Domain Imaging (OFDI) Assessment in Radiofrequency Ablation

NCT01439594
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
MGH OFDI Imaging
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Sep 2, 2026, 3:46 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Longitudinal Spatial Frequency Domain Imaging Study

NCT05672992
View directory record Official record
Conditions
Systemic Scleroderma
Interventions
Spatial-frequency domain imaging (SFDI)
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 2, 2026, 3:46 PM EDT