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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:21 PM EDT

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Showing 217–240 of 264 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spectacle Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Light Therapy for Fatigue N-of-1 Trials

NCT04707846
View directory record Official record
Conditions
Fatigue
Interventions
Bright Blue Light Commercial AYO Light Therapy Device, Dim Blue Light Commercial AYO Light Therapy Device
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 21, 2026, 5:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Control of Myopia Using Novel Spectacle Lens Designs

NCT03623074
View directory record Official record
Conditions
Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 10 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
13
States / cities
Whittier, California • Longwood, Florida • Pensacola, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Spectral Filtering in a Spectrally Adjustable Ocular Photosensitivity Analyzer

NCT04811079
View directory record Official record
Conditions
Photosensitivity
Interventions
419 nm Spectacle Filter, 437 nm Spectacle Filter, 456 nm Spectacle Filter, 476 nm Spectacle Filter, 373 nm Spectacle Filter
Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 30 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional

Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis

NCT07420751
View directory record Official record
Conditions
NF2-related Schwannomatosis
Interventions
Auto-captioning Glasses
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

NCT07095556
View directory record Official record
Conditions
Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions
Low-level laser therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 21, 2026, 5:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Is Y-Balance Test Predictive of Concussion

NCT05344703
View directory record Official record
Conditions
Concussion, Brain, Concussion; Eye
Interventions
Y Balance Plus Visual Perturbations, Y balance
Device · Diagnostic Test
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
11 Years to 19 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 21, 2026, 5:21 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Fatigue in Long-Haul Operations

NCT07761611
View directory record Official record
Conditions
Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Interventions
Caloric restriction, Light exposure
Behavioral · Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

NCT04128514
View directory record Official record
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spaeth/Richman Contrast Sensitivity Test

NCT01300949
View directory record Official record
Conditions
Glaucoma
Interventions
Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1

NCT06310135
View directory record Official record
Conditions
Sleep Quality
Interventions
Filtered Eyewear, Unfiltered Eyewear, No Filters
Device · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Menands, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 21, 2026, 5:21 PM EDT
Recruiting Not applicable Interventional

BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber

NCT07430735
View directory record Official record
Conditions
Dry Eye Disease (DED)
Interventions
BriTer Eyez Moisture Vue™ On Demand Disposable Moisture Chamber
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Phase 2 Interventional Results available

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

NCT05059041
View directory record Official record
Conditions
Down Syndrome, Refractive Errors
Interventions
Dilated Refraction, Non-Dilated Refraction
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Completed No phase listed Observational

Utility of a Survey Instrument to Predict Benefit From a Novel Treatment for Vertical Heterophoria

NCT01632787
View directory record Official record
Conditions
Binocular Vision Dysfunction, Vertical Heterophoria
Interventions
Questionnaires and Optometrist Prism Challenge/Treatment
Other
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomfield Hills, Michigan • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 21, 2026, 5:21 PM EDT
Not listed No phase listed Observational

Assessing Dynamic Reading Behaviors Using Eye-Tracking Tobii Glasses

NCT05684224
View directory record Official record
Conditions
Accommodation
Interventions
Dynamic accommodation
Behavioral
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
10 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 21, 2026, 5:21 PM EDT
Recruiting No phase listed Observational

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

NCT07427862
View directory record Official record
Conditions
Pain, Procedural Anxiety
Interventions
Meta Oculus Quest Pro, Pico 4, Pico G3
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
8 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Withdrawn Not applicable Interventional

Augmented Reality Heads-up Display to Improve Ultrasound Guided IV Access

NCT05710445
View directory record Official record
Conditions
Phlebotomy
Interventions
Augmented Reality
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional

Evaluating Altius Tinted Contact Lenses as an Option Managing for Post-Concussion Visual Syndrome

NCT07869927
View directory record Official record
Conditions
Post Concussion Symptoms
Interventions
ALTIUS® daily disposable performance-tinted contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Phase 2 Interventional Results available

Phase II Metronomic Dosing, Etoposide, Cyclophosphamide, D0 Prostate Cancer

NCT00176605
View directory record Official record
Conditions
Prostate Cancer
Interventions
Etoposide, Cyclophosphamide
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
7
States / cities
East Brunswick, New Jersey • Hamilton, New Jersey • Morristown, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 21, 2026, 5:21 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye

NCT06364657
View directory record Official record
Conditions
Sjogren's Syndrome, Dry Eye, Neurotrophic Keratitis
Interventions
Eye Exam
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 21, 2026, 5:21 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia

NCT02687581
View directory record Official record
Conditions
Amblyopia
Interventions
IO-therapy Glasses, patch
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 8 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2022 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional

Systematic Light Exposure for Fatigue in Breast Cancer Patients

NCT03217201
View directory record Official record
Conditions
Cancer-related Problem/Condition, Fatigue, Circadian Rhythm Disorders
Interventions
Light Glasses (Experimental), Light Glasses (Comparison)
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Duarte, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Results available

Trial of Overminus Spectacle Therapy for Intermittent Exotropia

NCT02807350
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Overminus treatment, Non-overminus treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 10 Years
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
59
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma

NCT01912599
View directory record Official record
Conditions
Normal-Tension Glaucoma
Interventions
Sensimed Triggerfish, Blood Pressure
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2016 · Synced Oct 21, 2026, 5:21 PM EDT
Completed Not applicable Interventional Results available

Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients

NCT03811249
View directory record Official record
Conditions
Presbyopia
Interventions
VisAbility™ Micro Insert
Device
Lead sponsor
VisDura, Inc.
Industry
Eligibility
45 Years to 60 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
13
States / cities
Orange, California • San Diego, California • Honolulu, Hawaii + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 5:21 PM EDT