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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:03 PM EDT

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Showing 169–192 of 264 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spectacle Clear all
Completed Not applicable Interventional Results available

A Wearable Morning Light Treatment for Postpartum Depression

NCT04845347
View directory record Official record
Conditions
Post Partum Depression
Interventions
Bright Light Therapy, Dim Light Therapy
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes

NCT03771274
View directory record Official record
Conditions
Cataract Bilateral, Presbyopia
Interventions
Tecnis ZLB00 & Symfony IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Peripheral Prism Glasses for Hemianopia

NCT00494676
View directory record Official record
Conditions
Homonymous Hemianopia
Interventions
High power (57 prism diopter) peripheral prism glasses, Low power sham peripheral prism glasses
Device
Lead sponsor
Alexandra Bowers
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
12
States / cities
Birmingham, Alabama • Palo Alto, California • Jupiter, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional

A Randomized Crossover Trial of Bright Light Therapy in Irritable Bowel Syndrome

NCT06676488
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Circadian Misalignment
Interventions
Re-Timer glasses, Placebo Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Glasses for Adolescent Delayed Sleep-Wake Phase Disorder

NCT04378933
View directory record Official record
Conditions
Delayed Sleep-Wake Phase Disorder
Interventions
Amber Glasses, Clear Lens Glasses
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
14 Years to 17 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 21, 2026, 2:03 PM EDT
Not yet recruiting Phase 4 Interventional

Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match

NCT07860567
View directory record Official record
Conditions
Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
Interventions
TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
Device
Lead sponsor
Dr. Daniel H. Chang, MD
Other
Eligibility
22 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice

NCT01909063
View directory record Official record
Conditions
Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
Interventions
Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
Dietary Supplement
Lead sponsor
Boston University
Other
Eligibility
6 Years to 10 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time

NCT06963736
View directory record Official record
Conditions
Sedentary Time, Cardiovascular Diseases, Prediabetes, Obesity
Interventions
Blue light, Eating, Standing
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
26 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial to Improve the Magnetic Levator Prosthesis

NCT03818204
View directory record Official record
Conditions
Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis, Stroke, Traumatic Brain Injury
Interventions
Magnetic Levator Prosthesis (MLP)
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
4 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens

NCT04124952
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
SightTrust Eye Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sunrise, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional

Brain-Computer Interface Communication Device for People With ALS

NCT07871071
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Cognixion ONE AR-BCI configuration, Cognixion ONE screen-based BCI configuration, Existing eye-gaze speech generating device
Device
Lead sponsor
Cognixion
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With Migraine

NCT01828684
View directory record Official record
Conditions
Migraine Disorders, Photophobia
Interventions
Therapeutic Lens Coating, Sham Lens Coating
Other
Lead sponsor
Bradley Katz
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Phase 4 Interventional

Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL

NCT01275118
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal IOL, crystalens Accommodating IOL
Device
Lead sponsor
Mark Packer, MD, FACS
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 28, 2014 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational Results available

AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study

NCT04126187
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
40 Years and older
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Myopia Control With a Innovative Spectacle Lens

NCT05174780
View directory record Official record
Conditions
Myopia
Interventions
innovative myopia control spectacle lens, Single vision spectacle lens
Device
Lead sponsor
Essilor International
Industry
Eligibility
6 Years to 12 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
9
States / cities
San Diego, California • Longwood, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Luminopia One Amblyopia Vision Improvement Study

NCT03608150
View directory record Official record
Conditions
Amblyopia
Interventions
Luminopia One, Refractive Correction
Device
Lead sponsor
Luminopia
Industry
Eligibility
4 Years to 7 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
22
States / cities
Los Angeles, California • Gainesville, Florida • Maitland, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancement of Emmetropization in Highly Hyperopic Infants

NCT03669146
View directory record Official record
Conditions
Hyperopia
Interventions
Glasses
Device
Lead sponsor
Donald O Mutti, OD, PhD
Other
Eligibility
8 Weeks to 15 Weeks
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Morning Light Exposure on Mood

NCT05616819
View directory record Official record
Conditions
Suicidal Ideation, Regulation, Emotion
Interventions
Active light exposure, Placebo light exposure
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 60 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational

Trifocal Intraocular Lens (IOL) Aberrometry Outcomes

NCT04196569
View directory record Official record
Conditions
Cataract
Interventions
Alcon Trifocal and Trifocal Toric Intraocular Lenses
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Orthokeratology in Myopia Control

NCT03465748
View directory record Official record
Conditions
Myopia
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 13 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Night Shift Nurses' Health and Reducing Burnout

NCT06829979
View directory record Official record
Conditions
Healthy
Interventions
Access to napping/relaxation room, Blue and green light blocking glasses
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Behaviors of Teachers of Invasive Bedside Procedures Using an Eye Tracking Device

NCT04235790
View directory record Official record
Conditions
Procedural Complication
Interventions
Eye Tracking Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2021 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional

Sleep TO Prevent Post-surgical Pain

NCT06976138
View directory record Official record
Conditions
Knee Osteoarthristis
Interventions
Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device, Sleep / Knee Osteoarthritis Education
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 2:03 PM EDT