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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spectacle Lenses Clear all
Completed Phase 3 Interventional

Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children

NCT00091923
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, Spectacles
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Sep 22, 2026, 5:36 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings

NCT05527041
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX Lens (EBLens)
Device
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
17 Years to 35 Years
Enrollment
1,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 22, 2026, 5:36 PM EDT
Terminated No phase listed Observational

Bilateral and Unilateral Amblyopia Treatment Study

NCT03780205
View directory record Official record
Conditions
Amblyopia
Interventions
Prescription glasses for bilateral amblyopia, Prescription glasses for unilateral amblyopia
Other
Lead sponsor
Salus University
Other
Eligibility
3 Years to 10 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Sep 22, 2026, 5:36 PM EDT
Not listed Not applicable Interventional

Manual Small Incision Cataract Surgery Outcomes in an Educational Setting

NCT02277314
View directory record Official record
Conditions
Cataracts
Interventions
Manual Small Incision Cataract Surgery
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Clinical Outcomes Following Implantation of Tecnis Synergy and Symfony Intraocular Lens

NCT05541796
View directory record Official record
Conditions
Cataract
Interventions
Intraocular lens
Device
Lead sponsor
George O. Waring IV
Other
Eligibility
40 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurolens Headache Study

NCT05070767
View directory record Official record
Conditions
Binocular Vision Disorder, Convergence Insufficiency, Headache, Computer Vision Syndrome
Interventions
Neurolens spectacle lens, Placebo spectacle lens
Device
Lead sponsor
Neurolens Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Conyers, Georgia • Perry, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Phase 2 Interventional Results available

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

NCT05059041
View directory record Official record
Conditions
Down Syndrome, Refractive Errors
Interventions
Dilated Refraction, Non-Dilated Refraction
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 22, 2026, 5:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence

NCT01191502
View directory record Official record
Conditions
Visual Acuity
Interventions
Not listed
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study

NCT05491746
View directory record Official record
Conditions
Diabetic Retinopathy, Low Vision
Interventions
Eye4, Placebo
Device · Other
Lead sponsor
Eyedaptic
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Correction of Farsightedness in Children Study

NCT00472212
View directory record Official record
Conditions
Hyperopia, Farsightedness
Interventions
Spectacles, Control
Device
Lead sponsor
Ohio State University
Other
Eligibility
6 Years to 11 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
4
States / cities
Chicago, Illinois • New York, New York • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Neurolens Convergence Insufficiency Study

NCT05087563
View directory record Official record
Conditions
Binocular Vision Disorder, Convergence Insufficiency, Computer Vision Syndrome
Interventions
Neurolens spectacle lens, Placebo spectacle lens
Device
Lead sponsor
Neurolens Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
Brea, California • Fort Collins, Colorado • Manchester, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With Migraine

NCT01828684
View directory record Official record
Conditions
Migraine Disorders, Photophobia
Interventions
Therapeutic Lens Coating, Sham Lens Coating
Other
Lead sponsor
Bradley Katz
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of the Avulux® Lenses as an Aid in Reducing the Impact of Migraine Headaches

NCT04341298
View directory record Official record
Conditions
Migraine
Interventions
11-point pain scale, Headache diary, Avulux®, Sham Avulux®
Other · Device
Lead sponsor
Avulux, Inc.
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

NCT04128514
View directory record Official record
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Spherical Soft Contact Lenses, Toric Soft Contact Lenses and Spectacles in Low Astigmats

NCT05056870
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day with HydraLuxe Technology for Astigmatism, ACUVUE Oasys 1-Day with HydraLuxe Technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
13
States / cities
Rocklin, California • Longwood, Florida • Maitland, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Results available

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation

NCT01515475
View directory record Official record
Conditions
Hyperopia
Interventions
Glasses
Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
12 Months to 71 Months
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Columbus, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 22, 2026, 5:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobility Performance in Daily Activities Among Children Wearing Spectacle Lenses

NCT07229352
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Glendale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Not applicable Interventional Results available

Symfony Toric Intraocular Lens Visual Outcomes

NCT03082599
View directory record Official record
Conditions
Cataract Bilateral, Astigmatism Bilateral
Interventions
Presbyopia and astigmatism correcting intraocular lens
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 22, 2026, 5:36 PM EDT
Recruiting Not applicable Interventional

Feasibility Tests for Various Prism Configurations for Visual Field Loss

NCT04424979
View directory record Official record
Conditions
Hemianopia, Homonymous, Tunnel Vision, Visual Field Defect, Peripheral, Visual Field Constriction Bilateral, Visual Field Defect Homonymous Bilateral
Interventions
High power prisms
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
7 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 22, 2026, 5:36 PM EDT
Completed Phase 4 Interventional Results available

Symfony vs Vivity in Dim Light

NCT06229106
View directory record Official record
Conditions
Cataract
Interventions
Symfony IOL, Vivity IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Sep 22, 2026, 5:36 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses

NCT00585026
View directory record Official record
Conditions
Refractive Error, Presbyopia, Asthenopia, Eyeglasses
Interventions
D-28 bifocal lenses and frame, Progressive addition computer lenses and frame
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 14, 2011 · Synced Sep 22, 2026, 5:36 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
View directory record Official record
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 22, 2026, 5:36 PM EDT
Terminated Not applicable Interventional

Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria

NCT00785135
View directory record Official record
Conditions
Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
Interventions
Lenses containing prismatic correction, Lenses not containing prismatic correction
Device
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
14 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Birmingham, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Sep 22, 2026, 5:36 PM EDT