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Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Speech Production Treatment Clear all
Terminated Not applicable Interventional Results available

Rhythm-based Intervention in Aphasia

NCT04581564
View directory record Official record
Conditions
Aphasia
Interventions
Rhythm-based speech therapy app (i.e., Speech Hero), Non-rhythm based (singing) application (conventional speech therapy)
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

AI-Assisted Treatment for Residual Speech Sound Disorders

NCT05988515
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Speech-Language Pathologist-led Speech Motor Chaining, Artificial Intelligence-led Speech Motor Chaining (CHAINING-AI)
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
9 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Not listed Not applicable Interventional

Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech

NCT06467136
View directory record Official record
Conditions
Apraxia, Oral, Apraxia of Speech
Interventions
Sound production treatment, Motor Imagery Practice
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Auditory-Perceptual Training Via Telepractice

NCT04858035
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Perceptual training, Production training
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
9 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Upper Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Intervention for Communication Quality of Life in Primary Progressive Aphasia

NCT07219680
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Semantic Dementia, Logopenic Progressive Aphasia (LPA), Nonfluent Aphasia, Progressive, Progressive Aphasia, Semantic Variant Primary Progressive Aphasia (svPPA), Semantic Aphasia, Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA), Logopenic Progressive Aphasia, Nonfluent Variant Primary Progressive Aphasia (nfvPPA), Nonfluent Progressive Aphasia
Interventions
Multicomponent Lexical Retrieval Cascade Training, Multicomponent Video Implemented Script Training in Aphasia
Behavioral
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Early Phase 1 Interventional

Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease

NCT06540989
View directory record Official record
Conditions
Parkinson Disease
Interventions
Immediate treatment, Deferred treatment
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
50 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Phase 1 Interventional

Treatment Targets in Spanish and English Bilingual Speech Intervention

NCT06416306
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Speech Intervention
Behavioral
Lead sponsor
Philip Combiths
Other
Eligibility
3 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia

NCT05901233
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS), Remotely supervised sham tDCS (RS-sham-tDCS), Lexical Retrieval Training (LRT), Video Implemented Script Training in Aphasia (VISTA)
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional

MIT Intensive Treatment Study

NCT06213376
View directory record Official record
Conditions
Stroke, Aphasia, Motor Speech
Interventions
Melodic Intonation Therapy, Video Feedback Performance Review
Behavioral
Lead sponsor
Nevada State University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Henderson, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter

NCT07354139
View directory record Official record
Conditions
Stuttering, Fluency Disorder
Interventions
High - Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Online Rotating Delivery of Perception/Production Enhanced Treatment for Rhotics

NCT06969521
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Visual acoustic biofeedback: ORDER, Perception Training: ORDER
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering

NCT07180628
View directory record Official record
Conditions
Stutter, Stuttering, Adult, Stuttering, Stuttering, Developmental
Interventions
Speech Production During functional magnetic resonance imaging (MRI)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

NCT05741853
View directory record Official record
Conditions
Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
Interventions
Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
Behavioral
Lead sponsor
Stephanie Grasso
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

tDCS Intervention in Primary Progressive Aphasia

NCT02606422
View directory record Official record
Conditions
Primary Progressive Aphasia, MCI, FTD
Interventions
Active HD-tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional Results available

Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes

NCT03977701
View directory record Official record
Conditions
Language Development Disorders, Speech Sound Disorder
Interventions
Phonological treatment, Morpheme treatment
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
3 Years to 6 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional Results available

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Phase 1 Interventional

Ultrasound Biofeedback for Speech Sound Disorders

NCT01905449
View directory record Official record
Conditions
Speech Sound Disorders
Interventions
Ultrasound visual feedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
8 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Visual Acoustic Biofeedback for RSE Via Telepractice

NCT04858022
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Visual-Acoustic Biofeedback Treatment, No Treatment
Behavioral · Other
Lead sponsor
Montclair State University
Other
Eligibility
9 Years to 15 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Upper Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Phase 4 Interventional

The Mechanism Versus PPI Trial

NCT06999577
View directory record Official record
Conditions
Laryngopharyngeal Reflux, Cough, Throat Clearing, Dysphonia, Reflux
Interventions
Omeprazole 40 MG, Laryngeal Recalibration Therapy, GERD Lifestyle Recommendations
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 89 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Deigo, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Characterizing the Impact of Presbyphonia on Social Interaction

NCT06441136
View directory record Official record
Conditions
Presbyphonia
Interventions
PhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index, The Edmonton Frail Scale, Vocal Effort Scale, Montreal Cognitive Assessment, Voice Handicap Index-10, Voice Problem Impact Scales, Cough Severity Index, Laryngoscopy, Acoustic, perceptual, and aerodynamic assessments
Other · Procedure
Lead sponsor
Matthew R. Hoffman
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Sep 21, 2026, 2:42 AM EDT
Not yet recruiting Not applicable Interventional

Speech Intervention Via Telepractice for Children With Repaired Cleft Palate

NCT07434375
View directory record Official record
Conditions
Cleft Palate Children, Speech Sound Disorder
Interventions
Speech therapy via teleprace, Face-to-face speech therapy
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
5 Years to 11 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional

Recasting or Book Reading by Parents or Clinicians

NCT05099328
View directory record Official record
Conditions
Developmental Language Disorder and Language Impairment
Interventions
Recast Therapy, Syntax Stories
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
4 Years to 9 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Newark, Delaware • College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Correcting Residual Errors With Spectral, Ultrasound, Traditional Speech Therapy

NCT03737318
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Biofeedback-ultrasound, Biofeedback--visual-acoustic, Traditional articulation treatment
Behavioral
Lead sponsor
New York University
Other
Eligibility
9 Years to 15 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Bloomfield, New Jersey • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Sep 21, 2026, 2:42 AM EDT
Completed Phase 1 Interventional Results available

Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors

NCT04625062
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Visual-acoustic biofeedback, Motor-based treatment
Behavioral
Lead sponsor
New York University
Other
Eligibility
9 Years to 15 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Bloomfield, New Jersey • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 21, 2026, 2:42 AM EDT