Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 80 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional

GyroStim for Post Concussion Syndrome

NCT07527663
Conditions
Post Concussion Syndrome
Interventions
Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
Device · Other
Lead sponsor
Neuroscience Group
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Appleton, Wisconsin
Terminated Phase 1 Interventional Accepts healthy volunteers

Brief Stresses Experimental Study

NCT03893617
Conditions
DNA Damage, Psychological Stress
Interventions
Propranolol, Placebo oral capsule, Acute stress task, No stress task
Drug · Behavioral
Lead sponsor
Dana Bovbjerg
Other
Eligibility
20 Years to 59 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Traumatic Brain Injury, Stroke, Brain Disease, Movement Disorders (Incl Parkinsonism), Central Nervous System Disease, Essential Tremor, Movement Disorders, Essential Tremor of Voice
Interventions
Deep Brain Stimulation (DBS) of the Motor Thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
ALS, PLS, PMA
Interventions
PAMSys Activity Monitoring System, Motor, Speech, and Handwriting Assessment
Device · Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
HIV
Interventions
Diurnal Variation Group, External Stress Group
Other
Lead sponsor
University of Melbourne
Other
Eligibility
25 Years to 55 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
San Francisco, California • Milwaukee, Wisconsin
Conditions
Amyotrophic Lateral Sclerosis, Brainstem Stroke, Muscular Dystrophies, Parkinson's Disease and Parkinsonism, Multiple System Atrophy, Brain Tumor Adult, Spinal Cord Injuries, Locked-in Syndrome
Interventions
BCI-FIT multi-modal access, BCI-FIT adaptive signal modeling, BCI-FIT active querying, BCI-FIT language modeling
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Laryngeal Cancer, Laryngectomy
Interventions
SpeakFree HME Hands Free Valve, Digital Occlusion, Digital Depression HME
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments

NCT04762043
Conditions
Rehabilitation of Speech and Language Disorders, Speech Disorders, Speech, Alaryngeal, Communication Aids for Disabled, Speech Perception, Speech Intelligibility
Interventions
Experimental System: MyoVoice, Reference System: Electrolarynx
Device
Lead sponsor
Altec Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Natick, Massachusetts
Conditions
Movement Disorders (Incl Parkinsonism), Stroke, Traumatic Brain Injury, Brain Diseases, Parkinson Disease, Essential Tremor, Movement Disorders
Interventions
Direct cortical stimulation and deep brain stimulation of motor thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

NCT00461487
Conditions
Behavior and Behavior Mechanisms
Interventions
Active control on hygiene and nutrition, Families Talking Together
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
11 Years to 14 Years
Enrollment
530 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Active, not recruiting Not applicable Interventional

AIH-induced Walking Recovery After Subacute SCI

NCT02632422
Conditions
Spinal Cord Injury
Interventions
Daily acute intermittent hypoxia (dAIH), dSHAM, Walking
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia • Cambridge, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Expectation of Unpleasant Events in Anxiety Disorders

NCT00055224
Conditions
Anxiety Disorders
Interventions
Threat of shock
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
921 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated No phase listed Observational Accepts healthy volunteers

Cochlear Implant Speech and Non-speech Sound Recognition

NCT03661970
Conditions
Deafness, Sound Perception, Quality of Sound
Interventions
Cognate Speech Synthesizer sound percepts
Other
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Kennewick, Washington
Completed No phase listed Observational Accepts healthy volunteers Results available

Speech, Linguistic and Acoustic Markers in Parkinson's Disease

NCT04273672
Conditions
Parkinson Disease, Cognitive Impairment, Mild, Speech
Interventions
Cognitive Battery, Voice, Speech and Language Analysis, Questionnaires and Clinical Assessments, DNA Analysis
Diagnostic Test · Behavioral · Genetic
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Cochlear Implants
Interventions
Cochlear Implants
Device
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
19 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Recruiting Not applicable Interventional Accepts healthy volunteers

Speech Motor Learning and Retention (Master Protocol)

NCT06467292
Conditions
Speech
Interventions
continuous theta-burst stimulation (cTBS), Adaptation, Single pulse Transcranial magnetic stimulation (TMS), fMRI
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Cochlear Implant Users
Interventions
Experiment 1: Syntactic and Semantic Context, Experiment 2: False Hearing and Context Overuse, Experiment 3: Two-Sentence Problem, Experiment 4: Cascading Effects on Discourse Comprehension, Experiment 5: Self-Paced Discourse Comprehension, Experiment 6: Clinical Application
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Waltham, Massachusetts • New York, New York
Conditions
Speech Sound Disorder
Interventions
Visual acoustic biofeedback: ORDER, Perception Training: ORDER
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Montclair, New Jersey
Conditions
Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders, Working Memory, Infant Open Heart Surgery
Interventions
Cogmed Working Memory Training
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 12 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Stroke
Interventions
Transitions of Care Coordinator, Usual Care
Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Recruiting Not applicable Interventional Accepts healthy volunteers

Speech Motor Learning and Retention (Aim 3)

NCT06492252
Conditions
Speech
Interventions
fMRI, Adaptation
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Anxiety Disorders, Depression
Interventions
Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
7 Years to 17 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2020
U.S. locations
1
States / cities
Piscataway, New Jersey
Recruiting Not applicable Interventional

Telerehabilitation for Aphasia (TERRA)

NCT04682223
Conditions
Aphasia, Stroke, Stroke Rehabilitation
Interventions
Semantically-focused therapy tasks, Phonologically-focused therapy tasks
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Subacute Stroke, Acute Stroke
Interventions
MindPod Dolphin VGT, Bimanual Arm Trainer VGT
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland