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ClinicalTrials.gov public records Last synced Oct 2, 2026, 4:58 AM EDT

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Showing 25–48 of 219 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Speech and language therapy Clear all
Completed Phase 2Phase 3 Interventional Results available

Augmenting Language Therapy for Aphasia: Levodopa

NCT01429077
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
levodopa/carbidopa, Placebo comparator
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 25, 2013 · Synced Oct 2, 2026, 4:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Delivering EMT Via Telehealth to Children and Families

NCT04604821
View directory record Official record
Conditions
Language Impairment
Interventions
Enhanced Milieu Teaching, Parent Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Months to 36 Months
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Oct 2, 2026, 4:58 AM EDT
Completed No phase listed Observational

Transcranial Direct Current Stimulation and Autism

NCT01603225
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention

NCT03260062
View directory record Official record
Conditions
Deafness, Bilateral
Interventions
Parent-Child Early Approaches to Raising Language Skills, Standard Care Speech therapy
Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
12 Months to 48 Months
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Direct Instruction Language for Learning in Autism Spectrum Disorder

NCT02483910
View directory record Official record
Conditions
Autism Spectrum Disorder, Moderate Language Delay
Interventions
Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx), Standard of care delivered via telehealth (e.g., Zoom or WebEx)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
4 Years to 7 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Oct 2, 2026, 4:58 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Evaluating Anodal tDCS Preceding Aphasia Therapy

NCT02249819
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Aerobic Exercise and Aphasia Treatment

NCT02999360
View directory record Official record
Conditions
Aphasia
Interventions
Language therapy, Background Music, Aerobic Exercise
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 2, 2026, 4:58 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia

NCT04614974
View directory record Official record
Conditions
Laryngomalacia, Gastro Esophageal Reflux
Interventions
Famotidine, Speech Language Therapy
Drug · Other
Lead sponsor
Reema Padia
Other
Eligibility
0 Months to 6 Months
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism

NCT01768806
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
PLAY Project Intervention for Autism, Special education pre-school
Behavioral
Lead sponsor
Richard Solomon MD, Plc
Other
Eligibility
3 Years to 5 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 2, 2026, 4:58 AM EDT
Recruiting Phase 1 Interventional

Treatment Targets in Spanish and English Bilingual Speech Intervention

NCT06416306
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Speech Intervention
Behavioral
Lead sponsor
Philip Combiths
Other
Eligibility
3 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Improving STEM Outcomes for Young Children With Language Learning Disabilities Via Telehealth

NCT04775199
View directory record Official record
Conditions
Language Development Disorders
Interventions
Language Intervention
Behavioral
Lead sponsor
Karla McGregor
Other
Eligibility
4 Years to 7 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 2, 2026, 4:58 AM EDT
Completed No phase listed Observational

Wellness and Quality of Life Perceptions of People With Traumatic Brain Injury

NCT04794894
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
outpatient rehabilitation
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Modulating Intensity and Dosage of Aphasia Scripts

NCT04138940
View directory record Official record
Conditions
Aphasia
Interventions
Script Training
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Oct 2, 2026, 4:58 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Treatment for Speech and Language in Primary Progressive Aphasia

NCT04881617
View directory record Official record
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 2, 2026, 4:58 AM EDT
Not listed Not applicable Interventional

Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech

NCT06467136
View directory record Official record
Conditions
Apraxia, Oral, Apraxia of Speech
Interventions
Sound production treatment, Motor Imagery Practice
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 2, 2026, 4:58 AM EDT
Completed No phase listed Observational

Real World Testing of a Brain-Computer Interface

NCT04026581
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury, Speech Disorders
Interventions
Speech generating device (SGD) evaluation including BCI access, Training and treatment
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Carnegie, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional Results available

Respiratory Muscle Strength Training in Presbyphonia

NCT03557775
View directory record Official record
Conditions
Presbylarynx
Interventions
Inspiratory Muscle Strength Training (IMST), Expiratory Muscle Strength Training (EMST), Voice Exercises
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 2, 2026, 4:58 AM EDT
Withdrawn Not applicable Interventional

tDCS to Treat Subacute Aphasia

NCT04048668
View directory record Official record
Conditions
Aphasia, Stroke, Acute
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Phase 3 Interventional Results available

Tinnitus Retraining Therapy Trial

NCT01177137
View directory record Official record
Conditions
Subjective Tinnitus
Interventions
Conventional sound generator (SG), Placebo sound generator (placebo SG), Standard of Care (SC), Directive Counseling (DC)
Device · Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
6
States / cities
Camp Pendleton, California • San Diego, California • Travis Air Force Base, California + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2018 · Synced Oct 2, 2026, 4:58 AM EDT
Recruiting Not applicable Interventional

Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)

NCT05651945
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident
Interventions
Cardiac rehabilitation program
Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 2, 2026, 4:58 AM EDT
Terminated Not applicable Interventional Results available

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NCT00613886
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 2, 2026, 4:58 AM EDT
Recruiting Not applicable Interventional

Remotely-supervised Neuromodulation in PPA

NCT07260253
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA)
Interventions
Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham
Behavioral · Device
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 2, 2026, 4:58 AM EDT
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 2, 2026, 4:58 AM EDT
Completed Not applicable Interventional

Virtually Assisted Home Rehabilitation After Acute Stroke-2

NCT05737524
View directory record Official record
Conditions
Stroke
Interventions
Telerehabilitation (VAST 2)
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2024 · Synced Oct 2, 2026, 4:58 AM EDT