Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 97 matching trials from the live ClinicalTrials.gov search.
Conditions
Cataracts
Interventions
Acrysof IQ (SN60WF) IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Visual Performance With Contact Lenses

NCT03705130
Conditions
Myopia
Interventions
Single Vision Contact Lens, Multifocal Contact Lens 1, Multifocal Contact Lens 2
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 39 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

Clinical Performance of Two Daily Disposable Soft Contact Lenses

NCT05138783
Conditions
Refractive Errors
Interventions
Verofilcon A contact lenses, Nesofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Tallahassee, Florida • Franklin Park, Illinois + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses Phase 2

NCT03168542
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Refractive Ametropia, Hyperopia, Myopia
Interventions
Lotrafilcon A spherical contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Timeline
2023
U.S. locations
4
States / cities
Tallahassee, Florida • Franklin Park, Illinois • Eden Prairie, Minnesota + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With a Daily Disposable Contact Lens

NCT04296877
Conditions
Contact Lens
Interventions
Daily Disposable Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparative Study of Two Marketed Spherical Soft Contact Lenses

NCT01582789
Conditions
Refractive Error
Interventions
enfilcon A, senofilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 38 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
2
States / cities
Pismo Beach, California • San Diego, California
Enrolling by invitation No phase listed Observational

Clinical Outcomes of Patients with LAL+ in At Least One Eye

NCT06650358
Conditions
IOL, Cataract
Interventions
Light Adjustable Lens+
Device
Lead sponsor
Frank A. Bucci, Jr., M.D.
Other
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3

NCT02950545
Conditions
Astigmatism
Interventions
Placebo Lenses, Spherical Lenses, Toric Lenses
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 39 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Astigmatism
Interventions
enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Irvine, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Lapsed Contact Lens Wearers Who Are Re-fit Into Senofilcon A Contact Lenses

NCT01990664
Conditions
Lapsed Contact Lens Wear
Interventions
senofilcon A, senofilcon A for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
10
States / cities
Jacksonville, Florida • Saint Augustine, Florida • Sarasota, Florida + 7 more
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Toric/Spherical Single Vision Contact Lens

NCT03970512
Conditions
Refractive Errors
Interventions
Apioc-A and Apioc-S Contact Lenses
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
18 Years to 35 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Athens, Ohio • Powell, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

How Does DT1 Sphere Perform in Current and Successful Acuvue MAX Wearers?

NCT06847230
Conditions
Contact Lens Comfort and Successful Refitting
Interventions
Dailies total 1 contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Completed Not applicable Interventional Results available

Clinical Validation of DACP Digital Design

NCT03567005
Conditions
Refractive Errors
Interventions
Nelfilcon A digital contact lenses, Nelfilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
5
States / cities
Bloomington, Illinois • Powell, Ohio • Brentwood, Tennessee + 1 more
Conditions
Myopia
Interventions
Pair 1 (ocufilcon D / ocufilcon D), Pair 2 (ocufilcon D / enfilcon A), Pair 3 (ocufilcon D / comfilcon A), Pair 4 (methafilcon A / methafilcon A), Pair 5 (methafilcon A / comfilcon A), Pair 6 (omafilcon A / comfilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Berkeley, California
Withdrawn No phase listed Observational Accepts healthy volunteers

Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs

NCT00886249
Conditions
Cataract, Vision
Interventions
Acrysof IQ, Acrysof Natural IOL
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Completed Not applicable Interventional Results available

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation

NCT01515475
Conditions
Hyperopia
Interventions
Glasses
Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
12 Months to 71 Months
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Columbus, Ohio • Salt Lake City, Utah
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Pseudoaccommodation of the Light Adjustable Lens: A Comparitive Study

NCT07176429
Conditions
Amplitude of Pseudoaccommodation
Interventions
Measurement of refractive error and amplitude of pseudoaccommodation
Device
Lead sponsor
Helm Vision Group
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Valencia, California
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Effect of Scatter on Visual Performance

NCT07443215
Conditions
Visual Acuity
Interventions
ACUVUE® OASYS 1-Day Sphere, ACUVUE® OASYS Multifocal
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Jacksonville, Florida
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Conditions
Cataract
Interventions
LAL+, Clareon Vivity Toric IOL
Device
Lead sponsor
The Eye Associates
Other
Eligibility
45 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bradenton, Florida
Completed Not applicable Interventional Accepts healthy volunteers

APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism

NCT04883099
Conditions
Presbyopia, Myopia, Hyperopia, Astigmatism
Interventions
APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
San Diego, California • Orlando, Florida • Lexington, Kentucky + 3 more
Conditions
Refractive Errors, Myopia
Interventions
Verofilcon A contact lenses, Nesofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Maitland, Florida • Medina, Minnesota • Powell, Ohio + 1 more