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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spherical Lenses Clear all
Completed No phase listed Observational

Clinical Outcomes of Patients with a Light Adjustable Lens (LAL) in At Least One Eye

NCT06016231
View directory record Official record
Conditions
IOL
Interventions
Light Adjustable Lens
Device
Lead sponsor
Bucci Laser Vision Institute
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2024 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional

An Assessment of Residual Spherical Aberration, Postoperative Total High Order Aberrations, and Functional Vision Correlation Following Intraocular Lens (IOL) Implantation

NCT01190631
View directory record Official record
Conditions
Cataracts
Interventions
Acrysof IQ (SN60WF) IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Bifocal Lenses In Nearsighted Kids

NCT02255474
View directory record Official record
Conditions
Refractive Errors
Interventions
Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
Device
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 11 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 26, 2026, 10:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

3D Video Virtual Reality Exposure Therapy Study

NCT02584387
View directory record Official record
Conditions
Acrophobia, Arachnophobia
Interventions
3D Video Virtual Reality Exposure Therapy
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 26, 2026, 10:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Euclid Phoenix Lens Design Trial

NCT06389916
View directory record Official record
Conditions
Myopia, Cornea
Interventions
Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
Device
Lead sponsor
Euclid Systems Corporation
Industry
Eligibility
6 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
5
States / cities
Costa Mesa, California • Saint Johns, Florida • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

NCT04840563
View directory record Official record
Conditions
Contact Lens Wear
Interventions
kalifilcon A daily disposable spherical soft contact lens, Dailies Total1 (delefilcon A) daily disposable spherical soft contact lens, Precision1 (verofilcon A) daily disposable spherical soft contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Lapsed Contact Lens Wearers Who Are Re-fit Into Senofilcon A Contact Lenses

NCT01990664
View directory record Official record
Conditions
Lapsed Contact Lens Wear
Interventions
senofilcon A, senofilcon A for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
10
States / cities
Jacksonville, Florida • Saint Augustine, Florida • Sarasota, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Characterization of Symptomatic Populations

NCT03319212
View directory record Official record
Conditions
Ametropia
Interventions
senofilcon A contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Initial Evaluation of Investigational Lenses Manufactured on a New Production Line

NCT03679741
View directory record Official record
Conditions
Visual Acuity
Interventions
CONTROL Lens, TEST Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
San Francisco, California • Jacksonville, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 25, 2019 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Total30 For Contact Lens Dropouts

NCT06967298
View directory record Official record
Conditions
Dry Eye, Contact Lens Complication, Contact Lenses
Interventions
T30 Contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of Investigational Lubricating Eye Drops

NCT05814367
View directory record Official record
Conditions
Visual Acuity
Interventions
Blink® Tears eye drops in a multidose bottle, Preservative-free investigational lubricating eye drops in a Novelia® eyedropper
Drug
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Jacksonville, Florida • Maitland, Florida • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of 4 Daily Disposable Soft Contact Lenses

NCT03349632
View directory record Official record
Conditions
Refractive Error
Interventions
verofilcon A contact lenses, senofilcon A contact lenses, stenfilcon A contact lenses, etafilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Maitland, Florida • Pensacola, Florida • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Sep 26, 2026, 10:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Euclid Phoenix Lens Design Trial 2

NCT06392607
View directory record Official record
Conditions
Myopia, Cornea
Interventions
Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
Device
Lead sponsor
Euclid Systems Corporation
Industry
Eligibility
6 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
5
States / cities
Edina, Minnesota • Sartell, Minnesota • North Brunswick, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 26, 2026, 10:13 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs

NCT00886249
View directory record Official record
Conditions
Cataract, Vision
Interventions
Acrysof IQ, Acrysof Natural IOL
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

NCT06044948
View directory record Official record
Conditions
Refractive Errors
Interventions
Delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
6
States / cities
Tallahassee, Florida • Eden Prairie, Minnesota • Garner, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Performance of Wearers of Stenfilcon A Contact Lenses After A Refit With Test Lenses

NCT03496701
View directory record Official record
Conditions
Myopia
Interventions
Test lens, control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
San Diego, California • Whittier, California • Sarasota, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens

NCT05984290
View directory record Official record
Conditions
Myopia
Interventions
orthokeratology lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
12 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Jacksonville, Florida • Bloomfield, Michigan • Edina, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism

NCT01852084
View directory record Official record
Conditions
Astigmatism
Interventions
enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations

NCT04789382
View directory record Official record
Conditions
Refractive Errors
Interventions
LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH, PV+Biotrue
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Maitland, Florida
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 26, 2026, 10:13 PM EDT
Completed No phase listed Observational

Air Optix Daily Wear Contact Lenses

NCT05827224
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive, Comfilcon A spherical soft contact lenses, Comfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Timeline
2023 – 2024
U.S. locations
5
States / cities
Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accommodative Relief for Uncomfortable Non-Presbyopes

NCT03544216
View directory record Official record
Conditions
Asthenopia
Interventions
Multifocal Contact Lens, Single Vision Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 40 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Approved and Investigational Contact Lenses

NCT03228212
View directory record Official record
Conditions
Visual Acuity
Interventions
CONTROL, TEST
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Jacksonville, Florida • East Lansing, Michigan • Pickens, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2

NCT03586648
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal, etafilcon A Sphere
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Whittier, California • Jacksonville, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 26, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation

NCT01515475
View directory record Official record
Conditions
Hyperopia
Interventions
Glasses
Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
12 Months to 71 Months
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Columbus, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 26, 2026, 10:13 PM EDT