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ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:38 PM EDT

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Showing 553–576 of 2,488 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal Clear all
Active, not recruiting Not applicable Interventional

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

NCT04982835
View directory record Official record
Conditions
Cervical Disc Degenerative Disorder
Interventions
M6-C Artificial Cervical Disc, ACDF
Device
Lead sponsor
Orthofix Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
21
States / cities
Phoenix, Arizona • Beverly Hills, California • Long Beach, California + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 25, 2026, 9:38 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Minimizing Nausea and Vomiting During Spinals for CS

NCT02872935
View directory record Official record
Conditions
Nausea, Vomiting
Interventions
Glycopyrrolate, Normal Saline
Drug
Lead sponsor
Kokila N Thenuwara
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 25, 2026, 9:38 PM EDT
Not yet recruiting Early Phase 1 Interventional

NeuroRise: Intrathecal CE-1 Treatment for Traumatic SCI

NCT07739043
View directory record Official record
Conditions
SCI - Spinal Cord Injury, SCI, Spinal Cord Injury
Interventions
Human allogeneic, culture expanded, UC-MSC
Drug
Lead sponsor
Cell Therapy LLC
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional

Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases

NCT04248543
View directory record Official record
Conditions
Spinal Metastases
Interventions
qMRI with Gadoteridol contrast agent
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 25, 2026, 9:38 PM EDT
Recruiting Not applicable Interventional

Neuromodulation to Enhance Motor Function in HSP

NCT07417943
View directory record Official record
Conditions
Hereditary Spastic Paraplegia
Interventions
transcutaneous spinal cord stimulation
Device
Lead sponsor
Rahul Sachdeva
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Enrolling by invitation Phase 2 Interventional

124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome

NCT06907849
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS), Cardiac Amyloidosis
Interventions
124I-evuzamitide
Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional

Walk-Training Program for Individuals With Chronic Spinal Cord Injury (SCI)

NCT03940274
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
walking training
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

High Rate Spinal Cord Stimulation (SCS) for Chronic Pain

NCT01624740
View directory record Official record
Conditions
Chronic Pain
Interventions
Low Rate Stimulation, High Rate Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2015 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional Results available

Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty

NCT01333943
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Study Group: Experimental, Control Group
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 25, 2026, 9:38 PM EDT
Completed No phase listed Observational

Adults With SMA Treated With Nusinersen

NCT04591678
View directory record Official record
Conditions
Spinal Muscular Atrophy
Interventions
nusinersen
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 25, 2026, 9:38 PM EDT
Not yet recruiting Not applicable Interventional

Neuromodulation to Overcome Severe Restless Legs Syndrome

NCT07780032
View directory record Official record
Conditions
Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS)
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
Marshall Holland
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2034
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Completed No phase listed Observational

A Study of Mood and Stress After Spinal Cord Injury

NCT01337908
View directory record Official record
Conditions
Spinal Cord Injury, Depression
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
19 Years and older
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
San Jose, California • Ann Arbor, Michigan • Detroit, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2012 · Synced Oct 25, 2026, 9:38 PM EDT
Terminated Not applicable Interventional

Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke

NCT04113525
View directory record Official record
Conditions
Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic, Hemiparesis, Upper Limb Hypertonia, CVA
Interventions
MyoRegulator™ System
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Oct 25, 2026, 9:38 PM EDT
Terminated Not applicable Interventional Results available

A Phase I/II Dose Escalation Study Using Extracranial Stereotactic Radiosurgery to Control Pain

NCT00802659
View directory record Official record
Conditions
Metastases
Interventions
Stereotactic radiotherapy
Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of "Smart Wheelchairs" to Provide Independent Mobility to Visual and Mobility Impairments

NCT00333762
View directory record Official record
Conditions
Blindness, Spinal Cord Injury
Interventions
Smart Power Assistance Module (SPAM), Smart Wheelchair Component System (SWCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
2
States / cities
Decatur, Georgia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Prevention of Low Blood Pressure in Persons With Tetraplegia

NCT00237770
View directory record Official record
Conditions
Hypotension, Spinal Cord Injury
Interventions
N-Nitro L-arginine-methylester (L-NAME), Head-up Tilt maneuver
Drug · Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Phase 2 Interventional

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

NCT00996073
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse
Biological
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
5
States / cities
Santa Monica, California • Greenwood Village, Colorado • Loveland, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Cervical Transforaminal Epidural Steroid Injection

NCT04544683
View directory record Official record
Conditions
Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
Interventions
Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimal Stimulation Programming for Spinal Peripheral Neuromodulation

NCT02346383
View directory record Official record
Conditions
Chronic Pain
Interventions
preset program
Device
Lead sponsor
Carolinas Center for Advanced Management of Pain
Other
Eligibility
22 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 25, 2026, 9:38 PM EDT
Active, not recruiting Not applicable Interventional

EKSO Trial: Powered Exoskeleton for Ambulation in Subjects With Spinal Cord Injury (SCI)

NCT01701388
View directory record Official record
Conditions
Spinal Cord Injuries or Similar Neurological Weakness
Interventions
Ekso exoskeleton
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Terminated Early Phase 1 Interventional Results available

Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

NCT05204290
View directory record Official record
Conditions
Epidural Spinal Tumors, Cancer
Interventions
Pembrolizumab, Stereotactic Body Radiation Therapy, Blood draws
Drug · Radiation · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Active, not recruiting No phase listed Observational

Long-Term Follow-up Study for Patients From AVXS-101-CL-101

NCT03421977
View directory record Official record
Conditions
Spinal Muscular Atrophy 1
Interventions
Onasemnogene Abeparvovec-xioi
Biological
Lead sponsor
Novartis Gene Therapies
Industry
Eligibility
Not listed
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 25, 2026, 9:38 PM EDT
Completed No phase listed Observational

Effect of Nusinersen on Adults With Spinal Muscular Atrophy

NCT03878030
View directory record Official record
Conditions
Adult Spinal Muscular Atrophy
Interventions
nusinersen
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 25, 2026, 9:38 PM EDT
Completed Early Phase 1 Interventional

Study of the Effect of GM-CSF on Macrophages in Ependymoma

NCT04408092
View directory record Official record
Conditions
Ependymoma, Recurrent Childhood, Ependymoma
Interventions
Granulocyte Macrophage Colony Stimulation Factor
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Months to 21 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
2
States / cities
Denver, Colorado • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 25, 2026, 9:38 PM EDT