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ClinicalTrials.gov public records Last synced Nov 1, 2026, 2:24 PM EST

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Showing 1633–1656 of 2,491 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal Clear all
Completed Not applicable Interventional

Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents

NCT02111278
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham Manipulation, Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Nov 1, 2026, 2:24 PM EST
Completed Phase 3 Interventional

Epidural Hydromorphone Compared With Hydromorphone Infusion in Treating Patients With Prostate Cancer Undergoing Radical Prostatectomy

NCT00003115
View directory record Official record
Conditions
Pain, Prostate Cancer
Interventions
hydromorphone hydrochloride
Drug
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2004
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2011 · Synced Nov 1, 2026, 2:24 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Spinal Manipulative Therapy: Dual-Task Performance

NCT00297934
View directory record Official record
Conditions
Balance
Interventions
Pro-adjuster mechanical spinal manipulative device
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2008 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Early Phase 1 Interventional

Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

NCT06735690
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Allogeneic Hematopoietic Stem Cell Transplantation, Anti-CD19-CAR CMV-specific T-lymphocytes, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Echocardiography, Leukapheresis, Lumbar Puncture, Magnetic Resonance Imaging, Multi-peptide CMV-Modified Vaccinia Ankara Vaccine, Multigated Acquisition Scan, Positron Emission Tomography, Transplant Conditioning, X-Ray Imaging
Procedure · Biological · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Self-balancing Personal Exoskeleton for SCI (WINY)

NCT07222033
View directory record Official record
Conditions
Spinal Cord Injury, Paraplegia and Tetraplegia
Interventions
Hands-free exoskeleton
Device
Lead sponsor
Wandercraft
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Completed Not applicable Interventional Results available

Treatment of Sleep-disordered Breathing in Patients With SCI

NCT02830074
View directory record Official record
Conditions
Spinal Cord Injury, Sleep-disordered Breathing, Spinal Cord Disease, Multiple Sclerosis
Interventions
Best practices PAP + patient Education +ongoing Support and Training, Sleep Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Nov 1, 2026, 2:24 PM EST
Terminated Not applicable Interventional

Paresthesia Free Spinal Cord Stimulation (PF-SCS)

NCT03670147
View directory record Official record
Conditions
SCS, Chronic Pain
Interventions
PF-SCS programming
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Phase 3 Interventional

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

NCT07466316
View directory record Official record
Conditions
Rhabdomyosarcoma
Interventions
Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Bone Scan, Computed Tomography, Cyclophosphamide, Dactinomycin, Irinotecan Hydrochloride, Lumbar Puncture, Lymph Node Biopsy, Magnetic Resonance Imaging, Positron Emission Tomography, Radiation Therapy, Resection, Survey Administration, Vincristine Sulfate, Vinorelbine Tartrate
Procedure · Drug · Biological + 2 more
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 50 Years
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
86
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 71 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Terminated Phase 1 Interventional

Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I

NCT00786968
View directory record Official record
Conditions
Spinal Cord Compression, Mucopolysaccharidosis I, Hurler-Scheie Syndrome, Scheie Syndrome, Lysosomal Storage Disease
Interventions
laronidase
Drug
Lead sponsor
Patricia I. Dickson, M.D.
Individual
Eligibility
8 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Nov 1, 2026, 2:24 PM EST
Not listed Phase 4 Interventional Accepts healthy volunteers

Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty

NCT01616342
View directory record Official record
Conditions
Extremity Injury
Interventions
Spinal cord stimulator
Device
Lead sponsor
Sceptor Pain Foundation
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2012 · Synced Nov 1, 2026, 2:24 PM EST
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)

NCT02197273
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
Interventions
Liposomal bupivacaine, Standard of care analgesia
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Nov 1, 2026, 2:24 PM EST
Completed Not applicable Interventional

Low Carbohydrate/High Protein Diet to Improve Metabolic Health

NCT03207841
View directory record Official record
Conditions
Spinal Cord, Metabolic Syndrome, Diabetes
Interventions
LC/HP
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Not applicable Interventional

PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm

NCT05195905
View directory record Official record
Conditions
Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Interventions
PMEG
Device
Lead sponsor
Konstantinos Arnaoutakis, MD
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Wesley Chapel, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Terminated Not applicable Interventional Accepts healthy volunteers

EMG Triggered Closed-Loop Stimulation for Spinal Cord Injury Individuals

NCT03806023
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
hand movements (signals from thumb muscle) triggered PNS and TMS
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Nov 1, 2026, 2:24 PM EST
Completed No phase listed Observational

Post Market Surveillance to Evaluate the Effectiveness the Polaris Deformity Spinal System

NCT01220505
View directory record Official record
Conditions
Spinal Deformity
Interventions
Surgery
Procedure
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
5
States / cities
Birmingham, Alabama • Loma Linda, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Nov 1, 2026, 2:24 PM EST
Active, not recruiting Phase 2 Interventional

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

NCT02713269
View directory record Official record
Conditions
Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Lung Non-Small Cell Cancer AJCC v7, Thyroid Gland Carcinoma
Interventions
Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Thermal Ablation Therapy
Procedure · Other · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Completed Phase 2 Interventional

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

NCT00996073
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse
Biological
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
5
States / cities
Santa Monica, California • Greenwood Village, Colorado • Loveland, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Nov 1, 2026, 2:24 PM EST
Completed Not applicable Interventional Results available

Spinal Cord Stimulation to Restore Cough

NCT00116337
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough, Trauma, Nervous System, Wounds and Injuries
Interventions
Spinal Cord Stimulation to restore cough, Expiratory Muscle Stimulator
Procedure · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Nov 1, 2026, 2:24 PM EST
Not yet recruiting Not applicable Interventional

Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)

NCT07689227
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Gait, Reduced Physical Activity, Lower Limb Functions, Walking Impairment, Mobility Impairment, Functional Mobility
Interventions
CLV, Sham
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Boston, Massachusetts • Dallas, Texas • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Not applicable Interventional

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

NCT05731986
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases, Central Nervous System Diseases, Hypotension, Orthostatic Hypotension, Cardiovascular Diseases, Acute Spinal Cord Injury, Blood Pressure
Interventions
Orthostatic challenge, Biostim-5 transcutaneous spinal stimulation - Mapping, Biostim-5 transcutaneous spinal stimulation - "Optimal" testing, Biostim-5 transcutaneous spinal stimulation - "Sham" testing
Diagnostic Test · Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Nov 1, 2026, 2:24 PM EST
Recruiting Not applicable Interventional

Erector Spinae Plane Blockade in Pediatric Scoliosis Surgery Patients

NCT04153994
View directory record Official record
Conditions
Scoliosis; Juvenile, Scoliosis; Adolescence
Interventions
Erector Spinae Plane Blockade
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Nov 1, 2026, 2:24 PM EST
Not listed No phase listed Observational Accepts healthy volunteers

Safety and Efficacy Study of Spinal Tethering

NCT02897453
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
The Spinal Tethering System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
10 Years to 23 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Nov 1, 2026, 2:24 PM EST
Completed Phase 2 Interventional Results available

Pilot Study to Evaluate The Effectiveness And Safety Of Axiom Worldwide Drx9000™ Spinal Decompression System

NCT00414596
View directory record Official record
Conditions
Low Back Pain
Interventions
DRX9000™
Device
Lead sponsor
NEMA Research, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
3
States / cities
Beverly Hills, California • Naples, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Nov 1, 2026, 2:24 PM EST