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ClinicalTrials.gov public records Last synced Nov 3, 2026, 9:26 AM EST

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Showing 1825–1848 of 2,493 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal Clear all
Completed Phase 1 Interventional

Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury

NCT04096950
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
MT-3921 Low dose
Biological
Lead sponsor
Tanabe Pharma America, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
13
States / cities
Sacramento, California • Chicago, Illinois • Urbana, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Nov 3, 2026, 9:26 AM EST
Not listed Not applicable Interventional

External Sensing and Neuromodulation to Assess Diabetic Pain Outcomes (XANADO)

NCT05537662
View directory record Official record
Conditions
Chronic Pain
Interventions
Standard of care neuromodulation therapy (SCS or DRG)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Nov 3, 2026, 9:26 AM EST
Terminated Phase 4 Interventional Results available

Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery

NCT03015961
View directory record Official record
Conditions
Postoperative Pain Management
Interventions
EXPAREL and bupivacaine HCl, Bupivacaine HCl
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
15
States / cities
Gilbert, Arizona • Phoenix, Arizona • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Palliative Strategies in Spinal Cord Injury (SCI)

NCT00594178
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Motorized bicycle exercise training
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2011 · Synced Nov 3, 2026, 9:26 AM EST
Recruiting Not applicable Interventional

Understanding Perinatal Spinal Cord Injury

NCT06808035
View directory record Official record
Conditions
Perinatal Spinal Cord Injury
Interventions
Activity-Based Recovery Training, Transcutaneous Spinal Cord Stimulation
Other · Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 8 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Completed No phase listed Observational

Diaphragm Pacing After Spinal Cord Injury

NCT02556125
View directory record Official record
Conditions
Injuries, Spinal Cord
Interventions
Diaphragm pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Completed No phase listed Observational

Cardiometabolic Risk, Obesity and Cardiovascular Disease in People With Spinal Cord Injury

NCT01204632
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Nov 3, 2026, 9:26 AM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?

NCT01243216
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Ultrasound
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Nov 3, 2026, 9:26 AM EST
Enrolling by invitation Not applicable Interventional

NIBS Therapy in Subacute Spinal Cord Injury

NCT06247904
View directory record Official record
Conditions
Traumatic Spinal Cord Injury, Tetraplegia/Tetraparesis
Interventions
Active rTMS, sham rTMS
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Nov 3, 2026, 9:26 AM EST
Suspended No phase listed Observational

Duke Spine Outcome Study (DSOS)

NCT04217525
View directory record Official record
Conditions
Spinal Tumor, Spinal Disorder
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional

A Pivotal Study of the Premia Spine TOPS™ System

NCT03012776
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Total Posterior Spine System (TOPS), Transforaminal Lumbar Interbody Fusion (TLIF)
Device · Procedure
Lead sponsor
Premia Spine
Industry
Eligibility
35 Years to 80 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
36
States / cities
Glendale, California • Los Angeles, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Nov 3, 2026, 9:26 AM EST
Recruiting Not applicable Interventional

Perspectives on Spinal Manipulative Therapy for Low Back Pain

NCT06590116
View directory record Official record
Conditions
Low Back Pain
Interventions
Physical therapy, Physical therapist provider
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Terminated Not applicable Interventional Results available

Pilot Study of Fosamax in Spinal Cord Injury

NCT01131884
View directory record Official record
Conditions
Spinal Cord Injury, Osteoporosis
Interventions
Fosamax, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2016 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional

Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases

NCT04248543
View directory record Official record
Conditions
Spinal Metastases
Interventions
qMRI with Gadoteridol contrast agent
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Nov 3, 2026, 9:26 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Rehab and Mechanical Ventilation

NCT07427121
View directory record Official record
Conditions
Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation, Sham Spinal Stimulation
Interventions
Spinal cord stimulation, Inspiratory Strength Training, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Active, not recruiting Phase 2 Interventional

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

NCT06413706
View directory record Official record
Conditions
Glioma
Interventions
Abemaciclib, Temozolomide
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
0 Years to 20 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Orange, California • Palo Alto, California • Indianapolis, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Recruiting Not applicable Interventional

Transcutaneous Electrical Stimulation for Stroke Patients

NCT06950593
View directory record Official record
Conditions
Upper Limb Hemiparesis Following Stroke
Interventions
Task Specific Training (TST), Transcutaneous electrical spinal cord stimulation (TESS), Sham transcutaneous electrical spinal cord stimulation (Sham TESS)
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury

NCT02392052
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Reinvention Protocol Participants, Wait List
Behavioral
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Nov 3, 2026, 9:26 AM EST
Completed Early Phase 1 Interventional

Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies

NCT01760226
View directory record Official record
Conditions
Diffuse Large B Cell Lymphoma, Post Transplant Lymphoproliferative Disorder, Primary Mediastinal (Thymic) Large B-cell Lymphoma
Interventions
DA-EPOCH-R for DLBCL, PTLD, AND PMBCL, Methotrexate, Etoposide, Doxorubicin, Vincristine, Rituximab, Cyclophosphamide, Prednisone, G-CSF
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 30 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Nov 3, 2026, 9:26 AM EST
Terminated Not applicable Interventional

Study of the Safety and Effectiveness of DIAM™ Spinal Stabilization System Versus Conservative Care

NCT00456378
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease
Interventions
DIAM™ Spinal Stabilization System, Conservative care
Device · Procedure
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years to 70 Years
Enrollment
311 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
29
States / cities
Scottsdale, Arizona • Beverly Hills, California • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Nov 3, 2026, 9:26 AM EST
Terminated No phase listed Observational

A Multicenter Prospective Registry for the Management of Degenerative Spine Disorders

NCT02802033
View directory record Official record
Conditions
Degenerative Diseases, Spinal Cord
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
908 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Nov 3, 2026, 9:26 AM EST
Completed Phase 2Phase 3 Interventional Results available

Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients

NCT01645787
View directory record Official record
Conditions
Spinal Muscular Atrophy
Interventions
4-aminopyridine, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Nov 3, 2026, 9:26 AM EST
Completed Not applicable Interventional

Effects of Cervical Manipulation on Cervical Rotation Motion and Shoulder Rotational Motion and Strength in Overhead Athletes

NCT06903793
View directory record Official record
Conditions
Cervical Spine, Manipulation, Spinal, Shoulder, Overhead Athlete
Interventions
cervical manipulation
Other
Lead sponsor
Sacred Heart University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Fairfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Nov 3, 2026, 9:26 AM EST