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ClinicalTrials.gov public records Last synced Nov 5, 2026, 11:17 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2161–2184 of 2,495 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Spinal Clear all

Conditions: Spinal Cord Injuries
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases, Spinal Disease, Spinal Stenosis, Spinal Instability, Fusion of Joint, Fusion of Spine, Spinal Fusion, Spine
Interventions: RTI Spine products; Device
Lead sponsor: Xtant Medical; Industry
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 7
States / cities: Hartford, Connecticut • Boca Raton, Florida • Delray Beach, Florida + 4 more

Conditions: Pregnancy
Interventions: Ultrasound; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Postdural Puncture Headache
Interventions: Epidural Blood Patch, Sphenopalatine Ganglion Block; Device · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 13 Years to 92 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 2
States / cities: New Brunswick, New Jersey

Conditions: Spinal Cord Injuries, Pressure Ulcer
Interventions: Dabir Air overlay; Device
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Headache
Interventions: Sphenopalatine ganglion Block, Epidural blood patch; Drug · Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Spinal Muscular Atrophy
Interventions: Not listed
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 5 Years to 20 Years
Enrollment: 24 participants
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Postsurgical Pain
Interventions: AYX1 Injection 660 mg / 6 mL, AYX1 Injection 1100 mg / 10 mL, Placebo Injection 6 mL, Placebo Injection 10 mL; Drug
Lead sponsor: Adynxx, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Sheffield, Alabama • Phoenix, Arizona

Conditions: Degenerative Disc Disease
Interventions: Natural Matrix Protein (NMP); Biological
Lead sponsor: Induce Biologics USA Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Shreveport, Louisiana

Conditions: Spinal Cord Injuries
Interventions: Wearable EMG/Vibration device; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 85 Years
Enrollment: 198 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Low Back Pain
Interventions: Epidural electrical spinal cord stimulator; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Malignant Neoplasm in the Leptomeninges, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8
Interventions: Digital Photography, Lumbar Puncture, Magnetic Resonance Imaging, Medical Device Usage and Evaluation, Biospecimen Collection; Other · Procedure · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Leptomeningeal Metastases
Interventions: Proton craniospinal irradiation (CSI); Radiation
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 10 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more

Conditions: Phantom Limb Pain
Interventions: Lower extremity amputation; Procedure
Lead sponsor: North Texas Veterans Healthcare System; Federal
Eligibility: 18 Years and older
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cervicogenic Headache
Interventions: Spinal Manipulation, Light Massage; Other
Lead sponsor: University of Western States; Other
Eligibility: 18 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Bloomington, Minnesota • Portland, Oregon

Conditions: Spinal Cord Injury
Interventions: Longitudinal; Other
Lead sponsor: James J. Peters Veterans Affairs Medical Center; Federal
Eligibility: 28 Years to 75 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Spinal Cord Injuries
Interventions: Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia; Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Spinal Muscular Atrophy (SMA), Carrier Screening, Genetic Testing
Interventions: Blood draw; Procedure
Lead sponsor: Natera, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: San Carlos, California

Conditions: Spinal Cord Injury, Paralysis
Interventions: Movement Assessment, MRI Scan, IntraSpinal Micro-Stimulation, Follow up clinical exam, Post Op MRI Scan, Follow up gait assessment; Other · Procedure
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 50 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Low Back Pain
Interventions: Lumbar medial branch nerve radiofrequency ablation (LRFA), Simulated LRFA with targeted steroid injections, AcTIVE-CBT, TBSCE; Procedure · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Multiple Sclerosis, Muscular Dystrophy, Post-polio Syndrome, Spinal Cord Injury
Interventions: Enhance Wellness; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 45 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Neck Pain, Shoulder Pain
Interventions: Exercise; Other
Lead sponsor: Timothy Uhl; Other
Eligibility: 18 Years to 99 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Autism
Interventions: Spinal Manipulative Therapy (SMT), SMT and Neuromuscular Reeducation; Procedure
Lead sponsor: Southern California University of Health Sciences; Other
Eligibility: 5 Years to 15 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Whittier, California

Conditions: Spinal Cord Injury, Hypotension
Interventions: Droxidopa; Drug
Lead sponsor: Bronx VA Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: The Bronx, New York

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Design and Delivery Preferences for Exercise Intervention in People With Spinal Cord Injury

Prospective SPINE Registry

Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base

Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache

Alternating Pressure Overlay on Weight Bearing Tissue Tolerance in People With Spinal Cord Injury

Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch.

Exploring the Physiologic, Pharmacodynamic, and Clinical Responses of Skeletal Muscle in Patients With Spinal Muscular Atrophy Treated With SMN-Directed Therapies

Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

Natural Matrix Protein™ (NMP™) in Interbody Lumbar Fusion

Vibration for Muscle Spasms After Spinal Cord Injury

Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases

Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation

Cervicogenic Headache Dose-Response

A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences

Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI

Multi-disease Carrier Screening Test Validation

Restoration of Standing and Walking With ISMS in Humans

Selecting Effective Combinations of Treatment for Low Back Pain

Enhance Wellness for Individuals With Long-Term Physical Disabilities

Surgeons Can Avoid Lasting Pain Through Exercise Literacy

Study of Chiropractic and Neuromuscular Reeducation as a Treatment for Autism Symptoms

A Dose Titration of Droxidopa in Patients With Spinal Cord Injury