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Showing 1–24 of 285 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal Cord Stimulation (SCS) Clear all
Recruiting Not applicable Interventional

Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

NCT07135583
View directory record Official record
Conditions
Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Incomplete Spinal Cord Injury
Interventions
Active Comparator: Single Intervention 1, Active Comparator: Single Intervention 2, Respiratory Resistance Exercise
Other · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Completed Not applicable Interventional

Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke

NCT04512690
View directory record Official record
Conditions
Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Epidural electrical stimulation (EES) of the cervical spinal cord
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
21 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 21, 2026, 5:06 PM EDT
Enrolling by invitation Not applicable Interventional

Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy

NCT07209514
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain (DPN)
Interventions
Implantable SCS with Closed Loop mechanism
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 21, 2026, 5:06 PM EDT
Completed Not applicable Interventional Results available

OPTIONS Spinal Cord Stimulation Programming Parameters

NCT02503787
View directory record Official record
Conditions
Pain, Intractable
Interventions
Spinal Cord Stimulation (SCS)
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
11
States / cities
Scottsdale, Arizona • Chula Vista, California • Wilmington, Delaware + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting Not applicable Interventional

The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

NCT05741788
View directory record Official record
Conditions
Spinal Cord Injuries, Chronic Pain
Interventions
Various Stimulation Patterns
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting No phase listed Observational

Patient Retrospective Outcomes (PRO)

NCT01550575
View directory record Official record
Conditions
Chronic Pain
Interventions
Non Boston Scientific Systems, Boston Scientific Systems
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2030
U.S. locations
87
States / cities
Lake Havasu City, Arizona • Phoenix, Arizona • Bakersfield, California + 76 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting No phase listed Observational

Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptiv™ Spinal Cord Stimulation Therapy

NCT07507422
View directory record Official record
Conditions
Chronic Pain, Intractable Pain
Interventions
Commercially available Inceptiv™ neurostimulation systems
Device
Lead sponsor
Medtronic
Industry
Eligibility
18 Years and older
Enrollment
970 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2034
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Terminated Not applicable Interventional

Algovita Spinal Cord Stimulation System Hi-Fi Study

NCT03622866
View directory record Official record
Conditions
Chronic Pain
Interventions
Ultra-high pulse width stimulation, Traditional pulse width stimulation
Device
Lead sponsor
Nuvectra
Industry
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
10
States / cities
Tucson, Arizona • Newport Beach, California • Santa Rosa, California + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting No phase listed Observational

Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain

NCT04658628
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Spinal Cord Associative Plasticity Study

NCT05163639
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions
Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Plus Spinal Stimulation for Cervical SCI

NCT04727866
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
Interventions
transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral, intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting Not applicable Interventional

Sensory Spinal Cord Stimulation

NCT07095036
View directory record Official record
Conditions
Pain Management, Pain, Intractable, Pain, Chronic Disease
Interventions
Spinal cord stimulation (SCS)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Spinal Cord Stimulation for the Treatment of Major Depressive Disorder

NCT03433339
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active transcutaneous spinal direct current stimulation, Sham transcutaneous spinal direct current stimulation
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 21, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity

NCT00399841
View directory record Official record
Conditions
Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
Interventions
Precision for Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Belleville, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Sep 21, 2026, 5:06 PM EDT
Terminated Not applicable Interventional

Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia

NCT03945331
View directory record Official record
Conditions
Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions
Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 21, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Results available

Spinal Stimulation During Exercise in Heart Failure

NCT02659202
View directory record Official record
Conditions
Heart Failure
Interventions
Precision Spinal Cord Stimulator System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 21, 2026, 5:06 PM EDT
Enrolling by invitation Not applicable Interventional

Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury

NCT06489106
View directory record Official record
Conditions
Spinal Cord Injury Cervical
Interventions
Activity based upper extremity training with and without stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
7 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Cervical Transcutaneous SCS for TBI

NCT07147816
View directory record Official record
Conditions
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
Device
Lead sponsor
Roberto de Freitas
Other
Eligibility
21 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Active, not recruiting Not applicable Interventional

Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity

NCT05669508
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
RISES-T System, Occupational/Physical Therapy
Device · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 55 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 21, 2026, 5:06 PM EDT
Withdrawn Not applicable Interventional

Noninvasive Spinal Cord Stimulation for Neurogenic and Idiopathic Overactive Bladder

NCT03753750
View directory record Official record
Conditions
Overactive Bladder, Incontinence, Urge, Neurogenic Bladder
Interventions
Noninvasive spinal cord stimulation
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 21, 2026, 5:06 PM EDT
Active, not recruiting Not applicable Interventional

Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic Neuropathy

NCT05777317
View directory record Official record
Conditions
Painful Diabetic Neuropathy
Interventions
10 kHz SCS, CMM alone
Device · Other
Lead sponsor
Nevro Corp
Industry
Eligibility
22 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Medford, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

NCT05265000
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
tSpinalStim
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 21, 2026, 5:06 PM EDT
Completed Phase 4 Interventional Results available

Spinal Cord Stimulation (SCS) Dosing Study

NCT03284411
View directory record Official record
Conditions
Back Pain, Leg Pain
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
10
States / cities
Chandler, Arizona • Lawrenceville, Georgia • Evansville, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Sep 21, 2026, 5:06 PM EDT
Recruiting No phase listed Observational

Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy

NCT05411523
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Spinal Cord Stimulation
Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 21, 2026, 5:06 PM EDT