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Showing 1–24 of 156 matching trials from the live ClinicalTrials.gov search.
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Testosterone and Neural Function in Men With Spinal Cord Injury

NCT06130449
Conditions
Spinal Cord Injury
Interventions
Natesto testosterone intranasal gel, Ayr Saline Nasal Gel
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Pressure Ulcers
Interventions
A fully implanted gluteal stimulation (GSTIM) system
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Stroke, Traumatic Brain Injury, Multiple Sclerosis
Interventions
Functional Electrical Stimulation, Normal care
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pomona, California
Conditions
Abortion in First Trimester, Pain
Interventions
Transcutaneous electrical nerve stimulation (TENS), Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Spinal Cord Injuries
Interventions
Exo + TSCS, Exo + Sham
Device
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Englewood, Colorado
Conditions
Spinal Cord Injuries, Blood Pressure Disorders
Interventions
ARC-IM System Implantation, ARC-IM Therapy (Group 1), ARC-IM Therapy (Group 2)
Procedure · Device
Lead sponsor
ONWARD Medical, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
12
States / cities
Little Rock, Arkansas • Englewood, Colorado • Miami, Florida + 8 more
Conditions
Aneurysmal Subarachnoid Hemorrhage
Interventions
spinal cord stimulation
Device
Lead sponsor
Konstantin V. Slavin
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Back Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Daphne, Alabama
Conditions
Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions
Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
Interventions
BurstDR Spinal Cord Stimulation
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Completed Not applicable Interventional Results available

Combining Mechanisms for Better Outcomes (COMBO)

NCT03689920
Conditions
Chronic Pain, Back Pain
Interventions
Boston Scientific Spectra WaveWriter™ Spinal Cord Stimulation (SCS) System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
15
States / cities
Phoenix, Arizona • La Jolla, California • Greenwood Village, Colorado + 12 more
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
10
States / cities
Carlsbad, California • Des Moines, Iowa • Edina, Minnesota + 6 more
Conditions
Spinal Cord Injury
Interventions
robotic training, spinal cord electrical stimulation, treadmill
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Parkinson Disease
Interventions
Spinal Cord Stimulator (SCS)
Device
Lead sponsor
Nora Vanegas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Paraplegia, Incomplete
Interventions
Exoskeleton Walking - with or without FES, Exoskeleton Sitting to Standing - with or without FES
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Raleigh, North Carolina
Completed Phase 4 Interventional Accepts healthy volunteers Results available

High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System

NCT02265848
Conditions
Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
Interventions
High frequency stimulation, Low frequency stimulation
Other
Lead sponsor
The Center for Clinical Research, Winston-Salem, NC
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Back Pain, Chronic Pain, Pain in Leg, Unspecified
Interventions
Precision Spinal Cord Stimulation System, Artisan Surgical Lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Charleston, South Carolina • Norfolk, Virginia
Conditions
Chronic Pain, Pain, Chronic
Interventions
Evoke Spinal Cord Stimulation System
Device
Lead sponsor
Saluda Medical Pty Ltd
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Little Rock, Arkansas • Santa Rosa, California • Gainesville, Florida + 1 more
Completed Not applicable Interventional Results available

PROLONG Prospective, Multi-center, Open-label, Post-market Study

NCT03908476
Conditions
Chronic Pain
Interventions
Burst-capable SCS system, DRG Stimulator
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
21
States / cities
Camarillo, California • Carlsbad, California • La Jolla, California + 18 more
Conditions
Cervical Spinal Cord Injury
Interventions
ExaStim Stimulation System
Device
Lead sponsor
Niche Biomedical, Inc. dba ANEUVO
Industry
Eligibility
22 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Denver, Colorado • Downer Grove, Illinois • Baltimore, Maryland + 2 more
Conditions
Chronic Pain
Interventions
High frequency spinal cord stimulation, Burst spinal cord stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Redwood City, California
Conditions
Chronic Low Back Pain, Chronic Leg Pain
Interventions
Therapy A spinal cord stimulation parameter set using BIO-RNA system and associated components, Therapy B spinal cord stimulation parameter set using BIO-RNA system and associated components
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
18
States / cities
Peoria, Arizona • Scottsdale, Arizona • Walnut Creek, California + 15 more
Conditions
Diabetic Peripheral Neuropathic Pain (DPN)
Interventions
Implantable SCS with Closed Loop mechanism
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Conditions
Low Back Pain, Back Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System, Standard interventional management of low back pain
Device · Procedure
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
18
States / cities
Little Rock, Arkansas • Walnut Creek, California • Greenwood Village, Colorado + 14 more