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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal Cord Stimulator (SCS) Clear all
Terminated Not applicable Interventional

Patient Experience Comparing Tonic Vs. Burst Spinal Cord Stimulation For Chronic Pain

NCT04159753
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 29, 2026, 5:24 PM EDT
Terminated Not applicable Interventional

Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion

NCT03976219
View directory record Official record
Conditions
Neuropathic Pain
Interventions
ECAPS Closed Loop SCS
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Sep 29, 2026, 5:24 PM EDT
Terminated No phase listed Observational

Quality of Life Outcomes in Spinal Cord Stimulation

NCT03249922
View directory record Official record
Conditions
Neuropathic Pain, Low Back Pain
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Timeline
2017 – 2018
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Effect of Epidural Stimulation on Muscle Activation and Sensory Perception

NCT04157400
View directory record Official record
Conditions
Chronic Pain
Interventions
Intraoperative Parameter Testing, Proprioception Testing During Stimulation, Gait Analysis During Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy

NCT06287736
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Spinal Cord Stimulator Implantation (SCS)
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

NCT05725499
View directory record Official record
Conditions
Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases, Cardiovascular Diseases, Trauma, Nervous System, Central Nervous System Diseases, Nervous System Diseases, Blood Pressure
Interventions
Biostim-5 transcutaneous spinal stimulator, Tilt-table orthostatic stress testing
Device · Diagnostic Test
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

NAVITAS and ENVISION - Study to Characterize Select Objective Metrics & Clinical Outcomes in Chronic Pain Patients With Boston Scientific Neurostimulation Systems

NCT03240588
View directory record Official record
Conditions
Pain, Chronic
Interventions
Neurostimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
16
States / cities
Phoenix, Arizona • Tucson, Arizona • Carlsbad, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 29, 2026, 5:24 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb

NCT06300996
View directory record Official record
Conditions
Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy 4, SMA
Interventions
Spinal Cord Stimulator (Octopolar Medtronic Vectris Leads)
Device
Lead sponsor
Marco Capogrosso
Other
Eligibility
16 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Stimulation With Wire Leads to Restore Cough

NCT01659541
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough, Trauma, Nervous System, Wounds and Injuries
Interventions
Expiratory muscle stimulator, Implantation of device
Device · Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation and Respiration After Injury

NCT05178056
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Stimulation, Breathing Exercises, Rehabilitation
Interventions
Spinal Cord Epidural Stimulation, Respiratory Training
Device · Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Evaluating Spinal Cord Stimulation for Stiff Person Syndrome

NCT06242678
View directory record Official record
Conditions
Stiff-Person Syndrome
Interventions
SCS trial lead
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012
View directory record Official record
Conditions
Spinal Cord Injuries, Neuromodulation
Interventions
Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
22 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Terminated Not applicable Interventional Results available

Spinal Stimulation During Exercise in Heart Failure

NCT02659202
View directory record Official record
Conditions
Heart Failure
Interventions
Precision Spinal Cord Stimulator System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

NCT05556902
View directory record Official record
Conditions
Blood Pressure, Low Back Pain, Hypertension
Interventions
Permanent Epidural Spinal Cord Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Exoskeleton and Spinal Cord Stimulation for SCI

NCT03096197
View directory record Official record
Conditions
Spinal Cord Injury, Ambulation Difficulty, Muscle Spasticity
Interventions
Exoskeleton-Assisted Walking, Transcutaneous Lumbosacral Stimulation (TLS)
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Repetitive Synchronized Associative Stimulation Neuromodulation Approach for Spinal Cord Injury Patients

NCT06494059
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
Intermittent theta burst stimulation (iTBS), Functional electrical stimulation (FES), Transcutaneous spinal cord stimulation (TSCS), Sham Intermittent theta burst stimulation (iTBS)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Terminated Not applicable Interventional

Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome

NCT00780390
View directory record Official record
Conditions
Complex Regional Pain Syndrome
Interventions
Autonomic Function Assessment
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

CoverEdge Algorithm Programming Study

NCT02492880
View directory record Official record
Conditions
Chronic Pain
Interventions
Precision Spectra™ SCS system programming features
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Denver, Colorado • Albany, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Electrically Evoked Compound Action Potentials Human Observation Medtronic System Study (ECHO-MDT)

NCT06499220
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
10
States / cities
Carlsbad, California • Des Moines, Iowa • Edina, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Value of Multiple Modalities Using the Spectra WaveWriter Spinal Cord Stimulator System

NCT03251937
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Spectra WaveWriter SCS System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
15
States / cities
Napa, California • Jupiter, Florida • Ocala, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Exploring the Effects of Spinal Cord Stimulation in Parkinson's Disease.

NCT03526991
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinal Cord Stimulator (SCS)
Device
Lead sponsor
Nora Vanegas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

NCT05968664
View directory record Official record
Conditions
Chronic Pain, Pain, Neuropathic, Neuropathic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Ashwin Viswanathan
Other
Eligibility
22 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 29, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation to Shorten Ventilator Dependence in ARDS Patients

NCT05928052
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Transcutaneous Biopac Electrical Stimulator
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 29, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees

NCT03027947
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Sep 29, 2026, 5:24 PM EDT