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ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:52 AM EDT

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Showing 1–24 of 160 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal Fusion Surgery Clear all
Recruiting Not applicable Interventional

ESP Block in MIS Lumbar Spine Surgery

NCT05856539
View directory record Official record
Conditions
Patients With Spinal Stenosis Indicated for MIS TLIF
Interventions
Erector spinae plane (ESP) block
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Not yet recruiting Not applicable Interventional

Evaluation of the Safety and Effectiveness of the CORUS™ Posterior Cervical Stabilization System 3D (PCSS 3D) for the Treatment of 2-level Cervical Degenerative Disease

NCT07721493
View directory record Official record
Conditions
Degenerative Disc Disease(DDD)
Interventions
Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
Device · Procedure
Lead sponsor
Providence Medical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Not applicable Interventional

SI Joint Stabilization in Long Fusion to the Pelvis

NCT04062630
View directory record Official record
Conditions
Sacroiliac Joint Disruption, Scoliosis Lumbar Region
Interventions
iFuse 3-D in Bedrock Configuration, Multilevel Lumbar Fusion surgery
Device · Procedure
Lead sponsor
SI-BONE, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
27
States / cities
Phoenix, Arizona • Little Rock, Arkansas • La Jolla, California + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Completed No phase listed Observational

Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability

NCT00726310
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis
Interventions
SpineLink® , SpineLink® II
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2009
U.S. locations
2
States / cities
San Diego, California • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 17, 2026, 4:52 AM EDT
Terminated No phase listed Observational

Bone Graft Materials Observational Registry

NCT00974623
View directory record Official record
Conditions
Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis, Spinal Deformity, Cervical Myelopathy, Failed Back Surgery Syndrome, Spinal Cord Neoplasms
Interventions
Bone graft substitute, autograft or allograft
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
12
States / cities
San Francisco, California • Atlanta, Georgia • Carrollton, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 17, 2026, 4:52 AM EDT
Completed No phase listed Observational

Validation of Triggered EMG Values for Pedicle Screws Using a Powered Screwdriver

NCT02064101
View directory record Official record
Conditions
Scoliosis
Interventions
Spinal Fusion
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 21 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 17, 2026, 4:52 AM EDT
Terminated Phase 4 Interventional Results available

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

NCT03115151
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Hydromorphone, Fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Phase 2 Interventional Results available

A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion

NCT03274453
View directory record Official record
Conditions
Spinal Fusion
Interventions
Ketamine, Saline
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
16 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Phase 2 Interventional Results available

Methadone vs Magnesium in Spinal Fusion

NCT01795495
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Methadone hydrochloride, Magnesium Sulfate, Remifentanil
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Coping After Pediatric Scoliosis Surgery

NCT04063670
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Video Intervention, Control
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Active, not recruiting No phase listed Observational

M6-C Post Approval Study (PAS)

NCT04122248
View directory record Official record
Conditions
Cervical Degenerative Disc Disease, Cervical Radiculopathy, Cervical Spinal Cord Compression, Cervical Disc Herniation
Interventions
standard radiographic imaging, cervical total disc replacement
Other · Device
Lead sponsor
Spinal Kinetics
Industry
Eligibility
21 Years to 68 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
21
States / cities
Phoenix, Arizona • Sun City West, Arizona • Beverly Hills, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Not applicable Interventional

SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery

NCT03835390
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
SIMDiscovery
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 17, 2026, 4:52 AM EDT
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
View directory record Official record
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Completed No phase listed Observational

Prospective Evaluation of Elderly Deformity Surgery

NCT02035280
View directory record Official record
Conditions
Adult Spinal Deformity
Interventions
Not listed
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
60 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
5
States / cities
San Francisco, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis

NCT00401518
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Non-randomized ACADIA® Facet Replacement System, Randomized ACADIA® Facet Replacement System, Randomized Instrumented posterolateral fusion (PLF)
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
21 Years to 85 Years
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2017
U.S. locations
28
States / cities
Beverly Hills, California • Los Angeles, California • Rancho Mirage, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 17, 2026, 4:52 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery

NCT06570577
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Inter-semispinalis Plane Block, Opioids
Procedure · Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 17, 2026, 4:52 AM EDT
Active, not recruiting Not applicable Interventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

NCT03570801
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Expert Panel Review
Other
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
662 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
16
States / cities
Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 17, 2026, 4:52 AM EDT
Not listed No phase listed Observational

Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

NCT00680264
View directory record Official record
Conditions
Cerebral Palsy, Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
8 Years to 21 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
12
States / cities
San Diego, California • Wilmington, Delaware • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 17, 2026, 4:52 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion

NCT00810212
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
PLF with autograft, PLF with NeoFuse
Procedure · Biological
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 17, 2026, 4:52 AM EDT
Recruiting Not applicable Interventional

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

NCT06528288
View directory record Official record
Conditions
Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
Interventions
Erector Spinae Plane Block, Subcutaneous Anesthesia
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 17, 2026, 4:52 AM EDT
Terminated Not applicable Interventional Results available

A Comparison of Stryker's Tritanium Posterior Lumbar Cage and PEEK Implant

NCT03817606
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Scoliosis
Interventions
Tritanium Posterior Lumbar Cage, AVS UniLIF PEEK Posterior Lumbar Cage
Device
Lead sponsor
Riverside Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Kankakee, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced Oct 17, 2026, 4:52 AM EDT
Terminated Phase 4 Interventional Results available

Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery

NCT03015961
View directory record Official record
Conditions
Postoperative Pain Management
Interventions
EXPAREL and bupivacaine HCl, Bupivacaine HCl
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
15
States / cities
Gilbert, Arizona • Phoenix, Arizona • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Oct 17, 2026, 4:52 AM EDT
Completed Phase 2 Interventional Results available

TXA in Spinal Fusion

NCT04272606
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
Drug · Diagnostic Test
Lead sponsor
Catherine R. Olinger
Other
Eligibility
18 Years to 90 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 17, 2026, 4:52 AM EDT
Withdrawn No phase listed Observational

ADDRESS - Adult Deformity Robotic vs. Freehand Surgery to Correct Spinal Deformity

NCT02058238
View directory record Official record
Conditions
Scoliosis, Kyphosis, Kyphoscoliosis, Spinal Deformity, Spondylosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 17, 2026, 4:52 AM EDT