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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal Manual Therapy Clear all
Completed Not applicable Interventional Results available

Assessment of Chiropractic Treatment Using Reaction and Response Times in Members of the Special Operation Forces (ACT2)

NCT02168153
View directory record Official record
Conditions
Physiological Measurements of Response and Reaction Times
Interventions
Chiropractic Manipulative Therapy, Wait-list
Other
Lead sponsor
RAND
Other
Eligibility
20 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 28, 2026, 8:23 PM EDT
Active, not recruiting Not applicable Interventional

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

NCT06906107
View directory record Official record
Conditions
Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
Interventions
Cervical Manipulation, Exercise, Mobilization
Procedure
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Rochester, Minnesota • Syracuse, New York • Waco, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

NCT06023498
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Manual Therapy and Exercise, Intramuscular Electroacupuncture
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Orlando, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 28, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional

Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy

NCT06312696
View directory record Official record
Conditions
Neck Pain
Interventions
SMT, Light Massage
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 39 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Low Back Pain

NCT00269321
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Manual treatment + home exercise (procedure+behavior), Supervised rehabilitative exercise+home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 28, 2026, 8:23 PM EDT
Not listed No phase listed Observational

Applying Pain Adaptability to Manual Therapy Practice

NCT05209659
View directory record Official record
Conditions
Musculoskeletal Manipulations, Low Back Pain
Interventions
Pragmatic Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Haslett, Michigan • Old Bridge, New Jersey • Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Phase 2 Interventional

Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury

NCT00448045
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Manual and mechanical assisted cough, Incentive spirometry
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Physical Therapy to Treat Chronic Pain in Survivors of Trauma

NCT03933189
View directory record Official record
Conditions
Chronic Pain, Disability Physical
Interventions
Physical Therapy
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT

NCT02437188
View directory record Official record
Conditions
Persistent Post-surgical Pain, Acceptance and Commitment Therapy, Substance Use Disorder
Interventions
ACT (Acceptance and Commitment Therapy)
Behavioral
Lead sponsor
Barbara A Rakel
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness

NCT06534931
View directory record Official record
Conditions
Muscle Weakness
Interventions
High velocity low amplitude thoracic spine manipulation, Sham
Procedure
Lead sponsor
University of New England
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Epidural Steroid Injection Versus Epidural Steroid Injection and Manual Physical Therapy and Exercise in the Management of Lumbar Spinal Stenosis

NCT00786981
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Epidural steroid injection plus physical therapy, Epidural steroid injection
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
50 Years to 90 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
4
States / cities
Denver, Colorado • Peoria, Illinois • Keesler Air Force Base, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 28, 2026, 8:23 PM EDT
Not yet recruiting Not applicable Interventional

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786
View directory record Official record
Conditions
Spine, Low Back Pain, Neck Pain
Interventions
Massage, Talk-based therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Manipulation Effects on Abdominal Muscles

NCT01745939
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham manipulation
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 4, 2014 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Phase 2 Interventional

Manipulation, Exercise, and Self-Care for Neck Pain

NCT00269360
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic + Supervised Rehabilitative Exercise, Supervised Rehabilitative Exercise, Self-care education
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Physical Therapy on Non-structural Medial Elbow Pain

NCT05537636
View directory record Official record
Conditions
Elbow Injuries and Disorders, Neuritis, Ulnar, Neuritis, Brachial, Neuritis; Nerve Root, Neuritis Median Nerve
Interventions
Rehabiltiation using exercise and manual therapy
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Manipulation, Exercise, and Self-Care for Low Back Pain

NCT00269347
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Spinal Manipulation, Exercise, Self-care
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 22, 2005 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Sacroiliac Dysfunction

NCT02373644
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
HVLA Thrust Manipulation and DN, Conventional Physical Therapy
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 28, 2026, 8:23 PM EDT
Terminated Not applicable Interventional

Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain

NCT06616272
View directory record Official record
Conditions
Brain Concussion, Neck Pain
Interventions
Cervical rehabilitation, Standard Concussion Care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 50 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Central Mechanism of Manual Therapy for Low Back Pain

NCT03078114
View directory record Official record
Conditions
Low Back Pain
Interventions
Spinal Manipulation, Placebo Spinal Manipulation
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Kansas City, Kansas • Leavenworth, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 28, 2026, 8:23 PM EDT
Not listed Phase 1Phase 2 Interventional

TRT in Combination With Electrical Stimulation and Standing: Effect on Muscle and Bone in Spinal Cord Injured Males

NCT02317640
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Testosterone Gel applied by a pump, Stand Training, Electrical Stimulation
Drug · Other · Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 58 Years · Male only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 28, 2026, 8:23 PM EDT
Not listed Not applicable Interventional

Effectiveness of the Freedom Bed as Compared to Alternating Pressure Mattress in Treatment of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and /or Spinal Cord Injury

NCT03118960
View directory record Official record
Conditions
Pressure Injury
Interventions
Freedom Bed, Group II Low Air Loss/Alternating Pressure Mattress
Device
Lead sponsor
Northeast Center for Rehabilitation and Brain Injury
Other
Eligibility
14 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lake Katrine, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain

NCT02036905
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical and thoracic mobilization, cervical and thoracic manipulation
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Solon, Ohio • Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Not applicable Interventional Results available

Effects of Breathing and Walking Treatments on Recovery Post-Spinal Cord Injury

NCT01272011
View directory record Official record
Conditions
Spinal Cord Injuries, Brown Sequard, Central Cord Syndrome
Interventions
Intermittent Hypoxia, Locomotor Training
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Sep 28, 2026, 8:23 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced Sep 28, 2026, 8:23 PM EDT