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Showing 1–24 of 148 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal cord stimulator Clear all
Completed Phase 1Phase 2 Interventional Results available

Functional Electrical Stimulation (FES) Driven Stepping in Individuals With Spinal Cord Injury

NCT01479777
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
FES Stepping (RT600 from Restorative Therapies, INC.)
Device
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2014 · Synced Sep 9, 2026, 9:42 AM EDT
Terminated Not applicable Interventional

Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion

NCT03976219
View directory record Official record
Conditions
Neuropathic Pain
Interventions
ECAPS Closed Loop SCS
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Sep 9, 2026, 9:42 AM EDT
Enrolling by invitation Not applicable Interventional

Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy

NCT07250828
View directory record Official record
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
Interventions
BurstDR Spinal Cord Stimulation
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Recruiting Phase 2 Interventional

From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects

NCT05661903
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator Set to Minimal/No Stimulation Setting, Usual Care, Positron Emission Tomography / Magnetic Resonance Imaging
Other · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Exploring the Effects of Spinal Cord Stimulation in Parkinson's Disease.

NCT03526991
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinal Cord Stimulator (SCS)
Device
Lead sponsor
Nora Vanegas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Ambulatory Closed-loop Stimulation for Bladder Control

NCT05740527
View directory record Official record
Conditions
Urinary Bladder, Neurogenic
Interventions
Noninvasive electrical stimulation of genital nerves
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Sep 9, 2026, 9:42 AM EDT
Terminated Not applicable Interventional

Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia

NCT03945331
View directory record Official record
Conditions
Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions
Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Spinal Cord Stimulation to Restore Cough

NCT00116337
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough, Trauma, Nervous System, Wounds and Injuries
Interventions
Spinal Cord Stimulation to restore cough, Expiratory Muscle Stimulator
Procedure · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Epi Stim to Facilitate Standing and Stepping

NCT02339233
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Standing and Stepping with spinal cord Epidural Stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 9, 2026, 9:42 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation to Shorten Ventilator Dependence in ARDS Patients

NCT05928052
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Transcutaneous Biopac Electrical Stimulator
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 9, 2026, 9:42 AM EDT
Recruiting Not applicable Interventional

Exoskeleton and Spinal Cord Stimulation for SCI

NCT03096197
View directory record Official record
Conditions
Spinal Cord Injury, Ambulation Difficulty, Muscle Spasticity
Interventions
Exoskeleton-Assisted Walking, Transcutaneous Lumbosacral Stimulation (TLS)
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Withdrawn Not applicable Interventional

War Wounded, a Comparison of Two Pain Management Approaches

NCT01620411
View directory record Official record
Conditions
Injuries, Pain
Interventions
Comprehensive Medical Management, Spinal Cord Stimulator
Other · Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

NCT01384448
View directory record Official record
Conditions
Chest Pain, Angina, Angina Pectoris, Coronary Artery Disease
Interventions
Stress Echocardiography, Coronary CT Angiography
Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
30 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Sep 9, 2026, 9:42 AM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees, 90-Day

NCT04547582
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
22 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Direct Comparison of Spinal Cord Stimulator Parameter Settings

NCT05283863
View directory record Official record
Conditions
Spinal Cord Stimulation, High-frequency Stimulation, High-density Stimulation
Interventions
High-frequency stimulation, Sham Stimulation
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 9, 2026, 9:42 AM EDT
Completed No phase listed Observational

NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators

NCT02284542
View directory record Official record
Conditions
Chronic Pain, Sciatica, Failed Back Surgery Syndrome
Interventions
Awake, Non-Awake
Procedure
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Bethlehem, Pennsylvania • Danville, Pennsylvania • Hershey, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Influence of Wearable Intensive Nerve Stimulation on Spasticity and Function in Persons With Spinal Cord Injury

NCT04130295
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle
Interventions
Wearable intensive nerve stimulator
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 9, 2026, 9:42 AM EDT
Recruiting Not applicable Interventional

At-Home Genital Nerve Stimulation for SCI Bowel

NCT06836739
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Genital nerve stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness Study of the Precision SCS Systems Adapted for High-Rate Spinal Cord Stimulation

NCT02093793
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
PRECISION SCS Adapted for High-Rate SCS
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
20
States / cities
Phoenix, Arizona • Carlsbad, California • La Jolla, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 9, 2026, 9:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Spinal Cord Stimulation in Chemotherapy Induced Neuropathy

NCT03764514
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Sep 9, 2026, 9:42 AM EDT
Active, not recruiting Not applicable Interventional Results available

Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury

NCT00583804
View directory record Official record
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
IST-12
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Wireless Spinal Cord Stimulation for Chronic Pain

NCT02514590
View directory record Official record
Conditions
Back Pain
Interventions
Freedom SCS System
Device
Lead sponsor
Curonix LLC
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Beverly Hills, California • Los Angeles, California • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Sep 9, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Combining Mechanisms for Better Outcomes (COMBO)

NCT03689920
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Boston Scientific Spectra WaveWriter™ Spinal Cord Stimulation (SCS) System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
15
States / cities
Phoenix, Arizona • La Jolla, California • Greenwood Village, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 9, 2026, 9:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

NCT07210411
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Tests of sympathetic inhibition, Tests of above level sympathetic activation, Testing of below level sympathetic activation, Epidural stimulation, Transcutaneous stimulation
Diagnostic Test · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 9, 2026, 9:42 AM EDT